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Naproxen

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Identification
Molecular formula
C14H14O3
CAS number
22204-53-1
IUPAC name
diethyl-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium;4-hydroxy-4-oxo-but-2-enoate
State
State

At room temperature, naproxen is in a solid state, typically in the form of a crystalline powder.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
378.70
Boiling point (Kelvin)
651.90
General information
Molecular weight
230.26g/mol
Molar mass
230.2640g/mol
Density
1.1780g/cm3
Appearence

Naproxen is usually found as a white to off-white, crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of diethyl-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium;4-hydroxy-4-oxo-but-2-enoate

The solubility of diethyl-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium;4-hydroxy-4-oxo-but-2-enoate can be influenced by several factors due to its complex structure. Understanding its solubility characteristics is crucial for both practical applications and theoretical considerations.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups in the structure can enhance solubility in polar solvents, while nonpolar regions can favor solubility in organic solvents.
  • Hydrogen Bonding: Ability to form hydrogen bonds may increase solubility in water, whereas compounds that lack this capability may exhibit lower solubility.
  • Temperature: Solubility typically increases with temperature; however, the behavior can vary depending on the precise compound and the solvent used.
  • pH Levels: The ionization state of the compound can change with pH, impacting its solubility, especially for ammonium salts.
  • Solvent Selection: Choice of solvent (polar vs. nonpolar) greatly affects solubility; compounds like this often require organic solvents for better dissolution.

It is notable that solubility is not a static property; as stated, "it is influenced by an array of conditions and chemical interactions." Therefore, experimentation under controlled conditions is necessary to pinpoint the precise solubility characteristics of this compound.


In summary, diethyl-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium;4-hydroxy-4-oxo-but-2-enoate's solubility is a nuanced topic, requiring consideration of multiple influencing factors for complete understanding.

Interesting facts

Interesting Facts about Diethyl-[2-[2-(1-Naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium;4-Hydroxy-4-Oxo-But-2-Enoate

This intriguing compound belongs to a class of organic molecules that presents fascinating features in both structure and potential applications. Here are some captivating insights:

  • Complex Structure: The compound features multiple functional groups and a unique framework, which includes a tetrahydrofuran ring and a naphthyl group, contributing to its chemical behavior and interactions.
  • Pharmacological Potential: Compounds of this nature are often investigated for their biological activities, which may include anti-inflammatory or anticancer properties. The combination of structural elements may enhance activity, making it a point of interest in medicinal chemistry.
  • Applications in Drug Development: Its unique design may allow for integration into drug delivery systems or as a lead compound in the search for new pharmaceutical agents. The functionality of this compound may enable targeted therapies.
  • Interdisciplinary Appeal: The synthesis and study of this compound can engage chemists, biologists, and pharmacologists alike. It bridges the gap between organic chemistry and pharmacology, exemplifying the interdisciplinary nature of modern scientific research.
  • Natural Product Analogue: The structure suggests similarities to natural products, hinting at the possibility of being a synthetic analogue of naturally occurring compounds with significant biological activity.

Overall, diethyl-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium;4-hydroxy-4-oxo-but-2-enoate is not just a chemical entity; it represents a fusion of creativity and innovation in the field of chemistry, exemplifying how complex molecular designs can lead to advancements in health and technology.