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Propidium Iodide

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Identification
Molecular formula
C27H34N4Cl3S
CAS number
25535-16-4
IUPAC name
diethyl-[2-[2-[4-(ethylammonio)phenyl]sulfanyl-3H-benzimidazol-1-ium-1-yl]ethyl]ammonium;trichloride
State
State

At room temperature, propidium iodide is typically in a crystalline solid form, characterized by its intense pigmentation and fluorescence properties.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.00
Boiling point (Celsius)
800.00
Boiling point (Kelvin)
1 073.00
General information
Molecular weight
668.94g/mol
Molar mass
668.9400g/mol
Density
1.0000g/cm3
Appearence

Propidium iodide is a red-fluorescing dye, often appearing as an orange or red powder that is highly water-soluble. It is commonly used in molecular biology as a fluorescent intercalating agent for staining.

Comment on solubility

Solubility of Diethyl-[2-[2-[4-(ethylammonio)phenyl]sulfanyl-3H-benzimidazol-1-ium-1-yl]ethyl]ammonium; Trichloride

Diethyl-[2-[2-[4-(ethylammonio)phenyl]sulfanyl-3H-benzimidazol-1-ium-1-yl]ethyl]ammonium; trichloride exhibits unique solubility properties that are influenced by its complex structure. A few notable points include:

  • Water Solubility: This compound is generally soluble in water due to the presence of ionic ammonium groups, which facilitate interaction with polar solvents.
  • Organic Solvents: It may also show solubility in certain organic solvents, depending on the solvent's polarity and the compound's specific interactions with it.
  • Temperature Effects: As with many ionic compounds, its solubility can be affected by temperature and pH. Higher temperatures often increase solubility.
  • Concentration: The solubility can also vary with concentration; higher concentrations may lead to precipitation depending on the solvent system.

In summary, the solubility characteristics of this compound make it versatile in varying environments, demonstrating a complex interplay between its ionic nature and the characteristics of the solvents it interacts with.

Interesting facts

Interesting Facts about Diethyl-[2-[2-[4-(ethylammonio)phenyl]sulfanyl-3H-benzimidazol-1-ium-1-yl]ethyl]ammonium Trichloride

Diethyl-[2-[2-[4-(ethylammonio)phenyl]sulfanyl-3H-benzimidazol-1-ium-1-yl]ethyl]ammonium trichloride is a fascinating compound, primarily recognized for its unique chemical structure and diverse applications in the field of chemistry. Here are some intriguing insights:

  • Complex Structure: This compound features a complex organic framework that incorporates a benzimidazole moiety, which is well-known for its biological activity and potential medicinal properties.
  • Charge Characteristics: The presence of ammonium ions in its structure gives this compound interesting ionic properties, making it a suitable candidate for studies in ionic liquids and materials science.
  • Pharmacological Potential: The phenyl and benzimidazole rings have been associated with numerous pharmacological activities. Compounds like these are often investigated for their anti-cancer, anti-inflammatory, and anti-microbial properties.
  • Sulfanyl Group: The sulfanyl (thiol) group in the compound can enhance its reactivity and interaction with various biological systems, pointing towards potential applications in drug design and development.
  • Research Uses: Researchers utilize this compound as a model in the study of ionic compound behavior, electrochemistry, and as a reagent in synthetic organic chemistry.

Moreover, the study of such compounds often leads to exciting discoveries that can bridge the gap between fundamental chemistry and applied sciences. As one prominent chemist famously said, "Chemistry is the central science, connecting the physical and life sciences." This compound exemplifies this connection, offering insights not just into its own properties but also into larger concepts within chemical research and applications.


Diethyl-[2-[2-[4-(ethylammonio)phenyl]sulfanyl-3H-benzimidazol-1-ium-1-yl]ethyl]ammonium trichloride truly stands at the crossroads of chemical innovation and medicinal chemistry, making it a subject of interest for scientists and students alike.

Synonyms
Benzimidazole, 1-(2-(diethylamino)ethyl)-2-((p-(ethylamino)phenyl)thio)-, trihydrochloride
1-(2-(Diethylamino)ethyl)-2-((p-(ethylamino)phenyl)thio)benzimidazole trihydrochloride
4929-82-2