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Dextromethorphan

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Identification
Molecular formula
C18H25NO
CAS number
125-71-3
IUPAC name
diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium
State
State

At room temperature, Dextromethorphan is typically in a solid state as a powder.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
165.00
Boiling point (Kelvin)
438.15
General information
Molecular weight
271.40g/mol
Molar mass
271.4040g/mol
Density
1.1953g/cm3
Appearence

Dextromethorphan typically appears as a white to slightly yellow crystalline powder. It is often odorless or has a faint aroma and is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of Diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium

The solubility of diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium is an intriguing topic, primarily due to the compound's complex structure. Several factors influence its solubility:

  • Polarity: The presence of hydroxyl groups and the quaternary ammonium structure suggests that the compound could exhibit polar characteristics, enhancing solubility in polar solvents like water.
  • Hydrogen bonding: The hydroxyl group can engage in hydrogen bonding, which often increases solubility in aqueous environments.
  • Electrostatic interactions: As a quaternary ammonium salt, this compound may dissolve well in solvents with available dipoles, promoting solubility through ionic interactions.
  • Hydrophobic interactions: The presence of phenyl groups indicates hydrophobic characteristics, which may reduce solubility in water but can enhance solubility in organic solvents.

In summary, one can expect diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium to exhibit variable solubility depending on the solvent's polarity and the solution's temperature. Generally speaking, compounds of this nature are well-studied in pharmaceutical applications, where solubility is critical for bioavailability.

Interesting facts

Interesting Facts about Diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium

Diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium is a fascinating compound that highlights the remarkable versatility of organic chemistry. Here are some interesting insights about this compound:

  • Pharmacological Potential: This compound exhibits promising properties in the field of medicinal chemistry, particularly due to its ability to modify neurotransmitter activity. Such compounds are often studied for their potential use in treating neurological disorders.
  • Synthetic Route: The synthesis of this compound involves intricate reactions, showcasing the elegance of organic synthesis techniques. The incorporation of multiple functional groups such as diphenyl and hydroxyl makes the synthesis a compelling challenge for chemists.
  • Structure-Activity Relationship (SAR): Analyzing the structure of this compound can lead to a deeper understanding of its biological activity. By modifying specific functional groups, scientists can tailor its properties for improved efficacy.
  • Ion-Transport Studies: The quaternary ammonium structure allows for the exploration of ion transport mechanisms across membranes, making this compound relevant in biochemistry and pharmacology.
  • Applications in Material Science: Beyond its pharmaceutical applications, this compound may also find uses in developing novel materials due to its unique electronic properties and ability to interact with other chemical species.

In summary, diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium represents a pathway to understanding complex biological interactions and possesses potential utility beyond the laboratory. As researchers continue to unravel its properties, this compound stands as a testament to the intricate connections between chemistry, biology, and material science.

Synonyms
Benzomethamine
17010-68-3
(2-(N-Benziloyl-N-methylamino)ethyl)diethylmethylammonium chloride
J12SSB9864
diethyl-[2-[(2-hydroxy-2,2-diphenylacetyl)-methylamino]ethyl]-methylazanium
UNII-J12SSB9864
BENZOMETHAMINE ION
BENZOMETHAMINE CATION
DTXSID40168799
CHEBI:135501
Q27281008
(2-(N-BENZILOYL-N-METHYLAMINO)ETHYL)DIETHYLMETHYLAMMONIUM
Ethanaminium, N,N-diethyl-2-((hydroxydiphenylacetyl)methylamino)-N-methyl-