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Diphenhydramine hydrobromide

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Identification
Molecular formula
C17H22BrNO
CAS number
147-24-0
IUPAC name
diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium;bromide
State
State

At room temperature, diphenhydramine hydrobromide exists as a solid.

Melting point (Celsius)
166.00
Melting point (Kelvin)
439.15
Boiling point (Celsius)
265.00
Boiling point (Kelvin)
538.15
General information
Molecular weight
318.24g/mol
Molar mass
318.2400g/mol
Density
1.2000g/cm3
Appearence

Diphenhydramine hydrobromide appears as a white or off-white crystalline powder. It is relatively stable under normal temperatures and pressures. It is soluble in water and ether, and has a slightly bitter taste followed by a cooling sensation.

Comment on solubility

Solubility of Diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium Bromide

The solubility of the compound diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium bromide is influenced by several factors, making it an interesting subject of study. Here are some key points regarding its solubility:

  • Nature of the bromide salt: As a quaternary ammonium salt, it is generally expected that the presence of bromide can enhance solubility in polar solvents, such as water.
  • Amine functional group: The methyl-amino group may contribute to solubility in both polar and nonpolar solvents due to its ability to form hydrogen bonds.
  • Hydroxyl group: The presence of the 2-hydroxy group on the acetyl moiety further increases the compound's affinity for polar solvents, aiding its dissolution.
  • Diphenyl structure: The bulky 2,2-diphenyl configuration may limit solubility in certain nonpolar solvents due to sterics.

In conclusion, while the solubility of diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium bromide is generally favorable in polar solvents, its performance in nonpolar mediums may be less optimal due to steric hindrance from its aromatic structures. Therefore, the effective solubility can vary significantly depending on the solvent system used.

Interesting facts

Interesting Facts about Diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium Bromide

Diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium bromide is a fascinating compound with various applications and properties that are worth exploring. Here are some intriguing aspects of this compound:

  • Pharmaceutical Potential: The unique structure of this compound makes it an interesting candidate for pharmaceutical applications, particularly in drug delivery systems. Its design may enhance the solubility and stability of active pharmaceutical ingredients.
  • Surface Activity: The presence of both hydrophilic and hydrophobic components in its structure suggests that it could exhibit surfactant properties, making it useful in formulations where interactions with water and oils are crucial.
  • Research Applications: This compound's structure may be of particular interest in research related to membrane technology and in the development of new materials for separating ionic species.
  • Bioactivity: Compounds with quaternary ammonium functionalities are often studied for their bioactive potential, including antimicrobial and anti-inflammatory properties. Understanding how this compound interacts with biological systems could lead to significant findings.

As noted by one research team, "The exploration of amine-based compounds can unveil unique pathways for therapeutic advancements." This highlights the significance of diethyl-[2-[(2-hydroxy-2,2-diphenyl-acetyl)-methyl-amino]ethyl]-methyl-ammonium bromide in current and future biochemical research.

Overall, the versatility and complex nature of this compound make it an exciting subject for further study in various fields, including medicinal chemistry, materials science, and pharmacology.

Synonyms
Benzomethamine bromide
MC 3199
3811-10-7
UNII-2P3X7KZ73R
DTXSID80959062
N,N-Diethyl-2-{[hydroxy(diphenyl)acetyl](methyl)amino}-N-methylethan-1-aminium bromide