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Ketoconazole

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Identification
Molecular formula
C26H28Cl2N4O4
CAS number
65277-42-1
IUPAC name
diethyl-[2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxyethyl]ammonium;chloride
State
State

At room temperature, Ketoconazole is in a solid state, specifically a crystalline powder.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
531.43g/mol
Molar mass
531.4300g/mol
Density
1.2300g/cm3
Appearence

Ketoconazole appears as a white or almost white crystalline powder. It is practically insoluble in water but freely soluble in methylene chloride and soluble in ethanol.

Comment on solubility

Solubility of Diethyl-[2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxyethyl]ammonium;chloride

The solubility of diethyl-[2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxyethyl]ammonium;chloride presents a unique case due to its complex structure. Factors that influence the solubility of this compound include:

  • Polarity: Due to the presence of multiple functional groups, the polarity of this compound can lead to varying interactions with solvents.
  • Size and Geometry: The bulky tricyclic moiety may hinder solvation and thus affect solubility in standard solvents.
  • Ammonium Ion: The quaternary ammonium aspect can enhance solubility in polar solvents such as water, but the exact behavior may vary.

In general, it is often observed that:

  1. The compound likely has limited solubility in nonpolar solvents.
  2. It may exhibit moderate to good solubility in organic solvents that can stabilize its molecular structure.
  3. The presence of chloride may promote interaction with aqueous environments, enhancing solubility in water.

It is essential to note that experimental data is crucial to fully understand the solubility characteristics of this compound, as theoretical predictions can be misleading due to the intricacies of its chemical structure.

Interesting facts

Interesting Facts About Diethyl-[2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxyethyl]ammonium Chloride

This compound, with its extensive and complex structure, showcases the fascinating interplay of organic chemistry and innovative material design. Here are some intriguing aspects of this unique molecule:

  • Unique Structural Attributes: The presence of the tricyclic framework in its structure contributes to rich chemical reactivity, making it an ideal candidate for various synthetic applications.
  • Potential Applications: Due to its ammonium group, this compound may exhibit properties suitable for use in biomedical applications, such as drug delivery systems or as a surfactant in formulations.
  • Heptaenylidene Configuration: The heptaenylidene moiety within the compound suggests it could have interesting optical properties, possibly making it useful in organoelectronics or in creating advanced light-harvesting materials.
  • Synthetic Versatility: Molecules with similar structures are often explored for generating new materials, indicating that diethyl-[2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxyethyl]ammonium chloride could serve as a key precursor in the synthesis of novel compounds.

As scientists and students continue to explore compounds such as this, they unlock new pathways to potential technologies and advanced materials. The journey of understanding these complex substances is not just about the science, but also about how they can influence various fields like pharmaceuticals, materials science, and even environmental chemistry.

In summary, the exploration of diethyl-[2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxyethyl]ammonium chloride not only broadens our chemical knowledge but also opens the door to finding practical uses in real-world applications!

Synonyms
LM 2918
5H-Dibenzo(a,d)cyclohepten-5-one, O-(2-(diethylamino)ethyl)oxime, monohydrochloride
25410-64-4
RefChem:305539