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Identification
Molecular formula
C10H13F6O5
CAS number
148555-64-6
IUPAC name
diethyl 2-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]propanedioate
State
State

At room temperature, the compound is in a liquid state.

Melting point (Celsius)
-29.00
Melting point (Kelvin)
244.15
Boiling point (Celsius)
135.00
Boiling point (Kelvin)
408.15
General information
Molecular weight
282.18g/mol
Molar mass
282.1770g/mol
Density
1.2400g/cm3
Appearence

The compound appears as a colorless liquid.

Comment on solubility

Solubility of Diethyl 2-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]propanedioate

The solubility of diethyl 2-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]propanedioate is influenced by its unique chemical structure, particularly the presence of trifluoromethyl groups. This structure can lead to a few interesting solubility characteristics:

  • Polar Nature: The hydroxyl group in the compound enhances its polarity, which generally increases solubility in polar solvents.
  • Effects of Fluorination: The trifluoromethyl groups introduce a higher electronegativity, often resulting in increased interactions with polar solvents like water.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents due to the presence of diethyl substituents, which can provide hydrophobic interactions.
  • Potential Challenges: While enhanced solubility can be achieved in certain environments, the very fluorinated nature may lead to lower solubility in non-polar solvents.

In summary, the solubility profile of this compound can be summarized by the following points: polar solvents may enhance solubility, while the overall fluorinated structure can yield complex solubility behavior. Understanding the solubility can aid in predicting its reactivity and potential applications in various fields.

Interesting facts

Interesting Facts about Diethyl 2-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]propanedioate

Diethyl 2-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]propanedioate is a fascinating compound, particularly due to the significant role of fluorinated compounds in modern chemistry. Here are some intriguing aspects of this compound:

  • Fluorine's Influence: The presence of multiple fluorine atoms contributes to unique physical and chemical properties, such as increased lipophilicity and enhanced bioactivity. Fluorinated compounds are often sought after in pharmaceutical research for their ability to modify the metabolism of drug candidates.
  • Diverse Applications: Due to its structural characteristics, this compound is likely to find use in various fields, including:
    • Pharmaceuticals: Fluorinated substrates demonstrate increased stability and bioavailability in drug formulations.
    • Agriculture: Potential use in agrochemical formulations, offering improved efficacy and environmental stability.
    • Material Science: It may serve as a building block for novel polymers with unique properties.
  • Synthetic Importance: The compound can be seen as a versatile intermediate in organic synthesis, allowing for the introduction of the trifluoromethyl group - a pivotal substituent in many agrochemicals and pharmaceuticals.
  • Environmental Considerations: Fluorinated compounds often raise concerns regarding environmental persistence and toxicity. Understanding their behavior in ecological systems is crucial for sustainable chemical development.

In summary, diethyl 2-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]propanedioate exemplifies the intricate interplay between structure and function in chemical compounds. As research delves deeper into fluorinated molecules, this compound stands out as a significant example of innovation within modern chemistry.

Synonyms
BRN 1915911
680-08-0
MALONIC ACID, (1-HYDROXY-2,2,2-TRIFLUORO-1-TRIFLUOROMETHYL)ETHYL-, DIETHYL ESTER
DTXSID70218190
1-Hydroxy-2,2,2-trifluoro-1-(trifluoromethyl)malonic acid diethyl ester
DTXCID90140681
Diethyl 2-[1-hydroxy-2,2,2-trifluoro-1-(trifluoromethyl)ethyl]malonate
Propanedioic acid,?2-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-,?diethyl ester