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Lidocaine

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Identification
Molecular formula
C14H22N2O2
CAS number
137-58-6
IUPAC name
diethyl-[2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethyl]ammonium;chloride
State
State

At room temperature, Lidocaine is typically found in its solid form when in pure state. However, for applications, it is often dissolved into an aqueous solution for ease of administration in medical settings.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
270.80g/mol
Molar mass
270.7980g/mol
Density
1.0260g/cm3
Appearence

Lidocaine typically appears as a white to off-white solid powder. It is commonly used in its hydrochloride form, which is water-soluble and also presented as a powder. Lidocaine is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of Diethyl-[2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethyl]ammonium; Chloride

The solubility of diethyl-[2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethyl]ammonium; chloride is quite notable due to its ionic nature imparted by the presence of the chloride ion. Here are some critical points about its solubility characteristics:

  • Ionic Compounds: As a quaternary ammonium salt, this compound typically exhibits good solubility in polar solvents, particularly in water. The ionic nature of the compound helps in the interaction with polar solvent molecules.
  • Temperature Influence: The solubility may increase with temperature, which is a common trait among many salts. This means that higher temperatures could enhance its dissolution in aqueous solutions.
  • Organic Solvents: It is also soluble in various organic solvents such as methanol and ethanol, allowing for flexibility in its application.
  • Structural Considerations: The presence of the methoxy group on the phenyl ring may enhance solubility in organic media through dipole-dipole interactions.
  • Factors Impacting Solubility: Factors such as pH, ionic strength of the solution, and the presence of competing ions can also influence the solubility of this compound.

“A compound's solubility is not just a property; it's a fundamental aspect that governs its reactivity and applicability in chemical processes.”

Understanding the solubility of diethyl-[2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethyl]ammonium; chloride thus reveals essential insights into its potential uses in various scientific and industrial contexts.

Interesting facts

Interesting Facts about Diethyl-[2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethyl]ammonium Chloride

This compound, known for its intricate structure, integrates both organic and inorganic chemistry elements. Here are some compelling facts:

  • Structure and Function: The compound contains an isoxazole ring, which is a five-membered ring featuring both nitrogen and oxygen. Isoxazoles often demonstrate unique properties, making them essential in pharmaceuticals.
  • Pharmaceutical Relevance: Many compounds featuring the isoxazole moiety have been recognized in drug discovery for their biological activities, including anti-inflammatory and analgesic properties.
  • Quaternary Ammonium Compound: The presence of diethylammonium in its structure indicates that it is a quaternary ammonium compound, which is significant in biochemistry due to its role as surfactants and in drug delivery systems.
  • Importance of Substituents: The addition of a 4-methoxyphenyl group enhances the compound's pharmacological profile. Methoxy groups can increase lipophilicity, improving the compound's ability to traverse cellular membranes.
  • Applications in Research: Compounds like this are frequently used in the investigation of neurotransmitter systems due to their ability to interact with receptors, potentially leading to insights into treating neurological disorders.

As you explore this compound further, consider how the interaction of its components contributes to its unique properties and applications. The combination of organic and medicinal chemistry present in diethyl-[2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethyl]ammonium chloride illustrates the beauty and complexity of synthetic chemistry.

Synonyms
3-(p-Methoxyphenyl)-5-(2-(diethylamino)ethyl)isoxazole hydrochloride
2148-75-6
ISOXAZOLE, 5-(2-(DIETHYLAMINO)ETHYL)-3-(p-METHOXYPHENYL)-, HYDROCHLORIDE