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Lidocaine Hydrochloride

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Identification
Molecular formula
C18H27ClN2O2
CAS number
6108-05-0
IUPAC name
diethyl-[2-[3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoyl]oxyethyl]ammonium;chloride
State
State

At room temperature, Lidocaine Hydrochloride is typically found as a solid in crystalline powder form. It is stable and may be used in solutions for various pharmaceutical applications.

Melting point (Celsius)
256.00
Melting point (Kelvin)
529.15
Boiling point (Celsius)
212.50
Boiling point (Kelvin)
485.60
General information
Molecular weight
306.82g/mol
Molar mass
306.8220g/mol
Density
1.0025g/cm3
Appearence

It is commonly found as a white or almost white crystalline powder. It may appear in the form of crystals or as a crystalline powder. It is highly soluble in water and ethanol, which makes it suitable for medical and pharmaceutical applications.

Comment on solubility

Solubility Characteristics

The solubility of diethyl-[2-[3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoyl]oxyethyl]ammonium chloride can be considered an intriguing subject. Generally, the solubility of ionic compounds in water is influenced by several factors, including:

  • Ionization: The presence of chloride ions typically suggests that the compound may exhibit good solubility in aqueous solutions.
  • Hydrophilicity vs. Hydrophobicity: The various functional groups present, such as the quinazoline moiety, introduce both hydrophilic and hydrophobic characteristics to the overall molecule, which can complicate solubility.
  • Temperature Dependence: Solubility can be temperature-dependent, often increasing with higher temperatures for many salts.

As a result, one might observe that this compound could be:

  • Highly soluble in polar solvents, particularly in water, due to the ionic nature of the ammonium chloride.
  • Moderately soluble in organic solvents owing to the hydrophobic segments introduced by the aromatic and quinazoline rings.

In conclusion, while the specific solubility data for diethyl-[2-[3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoyl]oxyethyl]ammonium chloride may vary, it is likely to exhibit a mixed solubility profile that aligns with the properties of its structural constituents. As with any chemical compound, empirical solubility tests should be conducted to determine exact behavior in relevant solvents.

Interesting facts

Interesting Facts about Diethyl-[2-[3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoyl]oxyethyl]ammonium Chloride

The compound diethyl-[2-[3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoyl]oxyethyl]ammonium chloride is a fascinating compound, especially in the domains of medicinal chemistry and biological research. It exhibits a unique combination of functional groups that contribute to its potential applications:

  • Quinazolinone Core: The structure includes a quinazolinone moiety, which is known for its biological activity. Compounds with this structure have been studied for their anticancer, anti-inflammatory, and antimicrobial properties.
  • Ammonium Group: The presence of a quaternary ammonium group imparts interesting properties such as increased solubility in polar solvents, which can enhance its bioavailability.
  • Ester Linkage: The ester group in the compound may contribute to its pharmacokinetics, potentially modifying how the compound's active ingredients are released in the body.

This compound can be investigated for its pharmacological potential and might exhibit therapeutic effects in various diseases, especially due to the quinazolin-3-yl structure that plays a significant role in many drug candidates. Researchers are keen to explore:

  • Its mechanism of action as a drug candidate.
  • Potential synergistic effects when combined with other therapeutic agents.
  • Exploration into its effects on specific biological pathways.

Furthermore, studies involving quinazolinone derivatives have shown promising results in inhibiting key enzymes related to disease progression, marking this compound as a candidate worth further scrutiny in drug discovery programs. As one of the compounds in the vast universe of synthetic organic chemistry, it exemplifies how a structured approach to compound design can lead to innovative formulations for addressing complex health challenges.

Synonyms
2-Metil-3-(2-carbossietildietilammino-6-metil-fenil)-4-chinazolone cloridrate [Italian]
3-Methyl-2-(2-methyl-4-oxo-3(4H)-quinazolinyl)benzoic acid 2-(diethylamino)ethyl ester HCl
Benzoic acid, 3-methyl-2-(2-methyl-4-oxo-3(4H)-quinazolinyl)-, 2-(diethylamino)ethyl ester, monohydrochloride
2-Metil-3-(2-carbossietildietilammino-6-metil-fenil)-4-chinazolone cloridrate