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Piperaquine dichloride

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Identification
Molecular formula
C29H32Cl2N3O
CAS number
4085-31-8
IUPAC name
diethyl-[2-[4-(4-piperidin-1-ium-1-ylbut-2-enyl)benzoyl]oxyethyl]ammonium;dichloride
State
State

Under standard conditions, piperaquine dichloride is a solid. It is typically storable in a dry place to maintain its efficacy and avoid degradation from moisture.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
535.49g/mol
Molar mass
535.4920g/mol
Density
1.2200g/cm3
Appearence

Piperaquine dichloride appears as a white or almost white crystalline powder. It is typically odorless and is known for its hygroscopic nature, meaning it can absorb moisture from the environment.

Comment on solubility

Solubility of Diethyl-[2-[4-(4-piperidin-1-ium-1-ylbut-2-enyl)benzoyl]oxyethyl]ammonium;dichloride

The solubility of the compound diethyl-[2-[4-(4-piperidin-1-ium-1-ylbut-2-enyl)benzoyl]oxyethyl]ammonium;dichloride, can be characterized by several key factors:

  • Polar Nature: This compound features a quaternary ammonium structure with polar characteristics due to the presence of multiple functional groups, which suggests a higher likelihood of solubility in polar solvents.
  • Solvent Compatibility: Diethyl-[2-[4-(4-piperidin-1-ium-1-ylbut-2-enyl)benzoyl]oxyethyl]ammonium;dichloride may exhibit good solubility in:
    • Water, indicated by the presence of ionic species such as chloride ions
    • Alcohols, due to the capable hydrogen bond formation
  • Hydrophilicity: The ionic nature contributed by the piperidinium and dichloride suggests significant hydration in aqueous environments, enhancing solubility.
  • Concentration Dependence: The solubility can be influenced by concentration, temperature, and pH of the solution medium, potentially leading to varying solubility profiles across different conditions.

In summary, the solubility of this complex compound can be viewed as promising in polar solvents, particularly water and alcohols, yet further empirical measurements would be necessary to establish exact solubility values and the influence of specific environmental factors.

Interesting facts

Interesting Facts about Diethyl-[2-[4-(4-piperidin-1-ium-1-ylbut-2-enyl)benzoyl]oxyethyl]ammonium; Dichloride

Diethyl-[2-[4-(4-piperidin-1-ium-1-ylbut-2-enyl)benzoyl]oxyethyl]ammonium; dichloride is a fascinating compound due to its synthesis, potential applications, and complex structure. Here are some intriguing aspects:

  • Complex Structure: The compound features a piperidinium unit, which is known for its role as a versatile building block in medicinal chemistry. The presence of a benzoyl moiety adds an aromatic character that is often associated with enhanced biological activity.
  • Ion Exchange Property: As a quaternary ammonium compound, it possesses distinct ionic characteristics which can be crucial in formulations such as surfactants and antimicrobial agents. The dichloride form indicates a stable ionic structure.
  • Pharmaceutical Potential: Compounds with similar structures have been explored for their effects on the nervous system, particularly in terms of their interactions with neurotransmitter receptors, making them potential candidates for drug development in neurology.
  • Design Innovations: The incorporation of a 4-piperidin-1-ium moiety may suggest modulation of biological activity, leveraging the compound's ability to traverse cell membranes and interact with specific biological targets.

Additionally, the compound's unique design allows for the possibility of fine-tuning its properties through various substitutions, making it an exciting subject for further research in pharmaceutical chemistry. "Understanding the unique interactions of such compounds can lead to groundbreaking therapeutic discoveries."

This compound exemplifies the blending of synthetic organic chemistry with potential real-world applications, highlighting the importance of interdisciplinary research.