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Lidocaine hydrochloride

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Identification
Molecular formula
C14H23ClN2O
CAS number
73-78-9
IUPAC name
diethyl-[2-(4-isopropylanilino)-2-oxo-ethyl]ammonium;chloride
State
State

Lidocaine hydrochloride is a solid at room temperature.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
214.00
Boiling point (Kelvin)
487.15
General information
Molecular weight
270.80g/mol
Molar mass
270.7970g/mol
Density
1.2380g/cm3
Appearence

Lidocaine hydrochloride appears as a white crystalline solid.

Comment on solubility

Solubility of Diethyl-[2-(4-isopropylanilino)-2-oxo-ethyl]ammonium Chloride

Diethyl-[2-(4-isopropylanilino)-2-oxo-ethyl]ammonium chloride is a fascinating compound when considering its solubility characteristics. Generally, solubility is influenced by several key factors, particularly the polarity of the compound.

  • Polarity: The presence of the ammonium group in the structure likely enhances solubility in polar solvents, especially in water.
  • Ion Exchange: As a salt, its dissociation into diethyl-[2-(4-isopropylanilino)-2-oxo-ethyl]ammonium+ and chloride- ions suggests a good degree of solubility in aqueous solutions.
  • Hydrophobic Interactions: The isopropyl and anilino groups introduce hydrophobic characteristics, which may affect solubility in organic solvents.

Therefore, it can be concluded that while diethyl-[2-(4-isopropylanilino)-2-oxo-ethyl]ammonium chloride is likely highly soluble in water due to its ionic nature, its solubility in non-polar solvents may be limited. As such, it is a prime candidate for applications requiring solubility in both polar and non-polar environments, making it a versatile compound in chemical processes.

Interesting facts

Interesting Facts About Diethyl-[2-(4-isopropylanilino)-2-oxo-ethyl]ammonium Chloride

Diethyl-[2-(4-isopropylanilino)-2-oxo-ethyl]ammonium chloride is a fascinating compound that intersects various fields, including organic chemistry, medicinal chemistry, and industrial applications. Here are some intriguing aspects of this compound:

  • Biological Activity: This compound is of particular interest due to its potential biological activities. Compounds incorporating ammonium functionalities often exhibit antimicrobial and antiviral properties, making them key candidates in drug development.
  • Structural Complexity: The presence of the 4-isopropylanilino moiety adds significant structural complexity which may influence the compound's interaction with biological targets. The oxo-ethyl group also contributes to its biochemical reactivity.
  • Synthetic Utility: This compound can serve as a starting material for the synthesis of other derivatives. The diethylammonium group is often utilized in organic synthesis due to its reactivity, leading to the creation of various functionalized compounds.
  • Chloride Ion Influence: The chloride ion in this compound can play a crucial role in solubility and stability. Its presence often influences the ionic interactions within biological systems or in reaction mechanisms.
  • Applications in Research: Researchers studying ionic liquids and their properties may find diethyl-[2-(4-isopropylanilino)-2-oxo-ethyl]ammonium chloride relevant for investigating solvent interactions and ionic conductivity.

In summary, diethyl-[2-(4-isopropylanilino)-2-oxo-ethyl]ammonium chloride is not only a compound of interest for its potential applications in medicinal chemistry but also serves as a versatile building block in organic synthesis. The intricate balance of its structure and chemical properties makes it a subject of ongoing research and exploration.

Synonyms
2-(Diethylamino)-4'-isopropylacetanilide monohydrochloride
14474-18-1
omega-Diethylamino isopropyl-4 acetanilide chlorhydrate [French]
ACETANILIDE, 2-(DIETHYLAMINO)-4'-ISOPROPYL-, MONOHYDROCHLORIDE
omega-Diethylamino isopropyl-4 acetanilide chlorhydrate