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detomidine hydrochloride

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Identification
Molecular formula
C16H16ClN5O2
CAS number
90036-47-6
IUPAC name
diethyl-[2-(5-methoxy-2-methyl-1-phenyl-indole-3-carbonyl)oxyethyl]ammonium;chloride
State
State

At room temperature, it is typically in a solid state as a crystalline powder.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
328.87g/mol
Molar mass
328.8710g/mol
Density
1.0000g/cm3
Appearence

Detomidine hydrochloride appears as a white to off-white crystalline powder. Its crystalline structure can be observed under a microscope, and it tends to clump slightly or form aggregates. It is odorless and has a bitter taste.

Comment on solubility

Solubility of Diethyl-[2-(5-methoxy-2-methyl-1-phenyl-indole-3-carbonyl)oxyethyl]ammonium Chloride

The solubility of diethyl-[2-(5-methoxy-2-methyl-1-phenyl-indole-3-carbonyl)oxyethyl]ammonium chloride can be influenced by various factors due to its complex molecular structure. Understanding its solubility characteristics is essential for different applications, particularly in pharmaceuticals and materials science.

Key Points on Solubility:

  • Solvent Polarity: This compound's solubility is likely to be higher in polar solvents due to its ammonium (-NH2) functionality, which can interact favorably with polar molecules.
  • Ionic Nature: As a quaternary ammonium salt, the presence of chloride ions enhances its ionic solubility, particularly in aqueous environments.
  • Temperature Dependence: The solubility might increase with temperature; thus, higher temperatures could lead to better dissolution in suitable solvents.
  • pH Sensitivity: The solubility may also be affected by the pH of the solution, especially if the compound can undergo protonation or deprotonation in acidic or basic conditions.

In general, it is expected that diethyl-[2-(5-methoxy-2-methyl-1-phenyl-indole-3-carbonyl)oxyethyl]ammonium chloride will exhibit good solubility in polar solvents, making it potentially suitable for various formulations. However, experimental data should be obtained to confirm these behaviors under specific conditions.

Interesting facts

Interesting Facts about Diethyl-[2-(5-Methoxy-2-Methyl-1-Phenyl-Indole-3-Carbonyl)Oxyethyl]Ammonium Chloride

Diethyl-[2-(5-methoxy-2-methyl-1-phenyl-indole-3-carbonyl)oxyethyl]ammonium chloride is a fascinating compound with intriguing properties and potential applications in various fields. Here are some captivating insights:

  • Pharmacological Potential: This compound belongs to a class of ammonium salts, which often exhibit significant biological activities. Its unique structure may contribute to novel pharmacological properties, possibly affecting various physiological pathways.
  • Indole Derivatives: The presence of the indole ring—known for its occurrence in many natural compounds, including serotonin and tryptophan—adds to its biological significance. Indoles often have implications in medicinal chemistry, being involved in the development of numerous drugs.
  • Methoxy and Methyl Substituents: The methoxy and methyl groups in its structure enhance the compound’s lipophilicity, which can improve its ability to cross biological membranes. Such modifications can influence its overall biochemical behavior and interactions within a living system.
  • Application in Drug Delivery: Due to its ammonium ion configuration, this compound might function effectively in drug delivery systems, targeting and releasing therapeutic agents in a controlled manner. This opens avenues for research in fields such as nanomedicine and biopharmaceuticals.
  • Research Significance: Because of its complex nature, researchers are likely to investigate this compound to uncover its full potential and mechanisms. The exploration of similar compounds can lead to breakthroughs in treating various diseases, particularly in areas related to oncology and neurology.

In conclusion, diethyl-[2-(5-methoxy-2-methyl-1-phenyl-indole-3-carbonyl)oxyethyl]ammonium chloride is not only a compound of chemical interest but also a potential player in the world of medicine and biochemistry. Its unique compositions and substituents open the door to a wealth of research opportunities, signaling the importance of continuing exploration in this exciting field.

Synonyms
18235-87-5
Indole-3-carboxylic acid, 5-methoxy-2-methyl-1-phenyl-, 2-(diethylamino)ethyl ester, monohydrochloride
Of-2436
OF 2436