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Diethyl 2-acetamidopropanedioate

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Identification
Molecular formula
C9H15NO5
CAS number
1068-90-2
IUPAC name
diethyl 2-acetamidopropanedioate
State
State

At room temperature, diethyl 2-acetamidopropanedioate is in a liquid state. It presents the typical characteristics of organic esters, including volatility and moderate evaporation under room conditions.

Melting point (Celsius)
-5.00
Melting point (Kelvin)
268.15
Boiling point (Celsius)
284.00
Boiling point (Kelvin)
557.15
General information
Molecular weight
231.23g/mol
Molar mass
231.2470g/mol
Density
1.1330g/cm3
Appearence

Diethyl 2-acetamidopropanedioate typically appears as a colorless to light yellow liquid. Its clarity and low viscosity are characteristic of many ester compounds.

Comment on solubility

Solubility of Diethyl 2-Acetamidopropanedioate

Diethyl 2-acetamidopropanedioate, a complex organic compound, exhibits specific solubility characteristics that are worth noting. Understanding solubility is crucial in chemical applications, particularly in synthesis and formulation. Here are some key points regarding the solubility of this compound:

  • Solvent Compatibility: Diethyl 2-acetamidopropanedioate is generally soluble in organic solvents such as ethanol, methanol, and acetone, making it suitable for organic reactions and processes.
  • Polar vs. Non-Polar Solvents: The compound may demonstrate limited solubility in non-polar solvents. Its polar functional groups contribute to better solubility in polar solvents.
  • Temperature Dependence: Solubility can be affected by temperature; increased temperatures often enhance solubility, thus facilitating reactions or extractions.

As a general observation, solubility is influenced not just by the molecular structure, but also by the interactions between solvent and solute. In dissolution processes, the ability of the solvent molecules to surround and interact with the solute molecules is paramount.

To conclude, it is essential to consider the specific conditions when working with diethyl 2-acetamidopropanedioate to achieve optimal solubility and functionality in your chemical applications.

Interesting facts

Interesting Facts about Diethyl 2-Acetamidopropanedioate

Diethyl 2-acetamidopropanedioate, often regarded as an intriguing intermediate in organic synthesis, showcases a diverse range of properties and applications. This compound, belonging to the category of diesters, has captured the attention of chemists for several reasons:

  • Synthesis Versatility: Diethyl 2-acetamidopropanedioate can be synthesized through various pathways, making it a valuable precursor for the creation of other complex molecules.
  • Pharmaceutical Relevance: Compounds derived from diethyl 2-acetamidopropanedioate often exhibit biological activity, highlighting its potential in the field of drug development and medicinal chemistry.
  • Diverse Functional Groups: The presence of both acetamido and diethyl ester groups allows for extensive reactivity, which can lead to the formation of various derivatives useful in different chemical reactions.
  • Research Importance: This compound serves as a focal point in studies related to organocatalysis and is often used as a starting material in the synthesis of more complex organic compounds.

As noted in the literature, "the true beauty of diethyl 2-acetamidopropanedioate lies in its ability to bridge simple esters and more complex bioactive molecules." This characteristic solidifies its place in both academic research and industrial applications.

Furthermore, the study of diethyl 2-acetamidopropanedioate can lead to a better understanding of ester reactivity and its implications in synthetic organic chemistry, paving the way for new discoveries and advancements in chemical synthesis.

Synonyms
Diethyl acetamidomalonate
1068-90-2
Diethyl 2-acetamidomalonate
ACETAMIDOMALONIC ACID DIETHYL ESTER
Diethyl acetylaminomalonate
Diethyl acetaminomalonate
Propanedioic acid, (acetylamino)-, diethyl ester
Diethyl (N-acetylamino)malonate
(Acetylamino)propanedioic acid diethyl ester
Malonic acid, acetamido-, diethyl ester
NSC 7645
Diethylester kyseliny acetylaminomalonove
HSDB 2664
EINECS 213-952-9
Propanedioic acid, 2-(acetylamino)-, 1,3-diethyl ester
BRN 0783883
4VDX81E00W
AI3-52334
NSC-7645
Diethylester kyseliny acetylaminomalonove [Czech]
DTXSID6061446
4-04-00-02993 (Beilstein Handbook Reference)
ACETAMIDOMALONIC ACID DIETHYL ESTER [HSDB]
DIETHYLESTER KYSELINY ACETYLAMINOMALONOVE (CZECH)
Diethyl 2acetamidomalonate
DTXCID1033030
Malonic acid, acetamido, diethyl ester
Propanedioic acid, (acetylamino), diethyl ester
213-952-9
ethyl acetamidomalonate
inchi=1/c9h15no5/c1-4-14-8(12)7(10-6(3)11)9(13)15-5-2/h7h,4-5h2,1-3h3,(h,10,11
diethyl 2-acetamidopropanedioate
1,3-diethyl 2-acetamidopropanedioate
diethyl (acetylamino)malonate
2-Acetylaminomalonic acid diethyl ester
Diethyl acetamidomalonic acid
Acetaminomalonic acid diethyl ester
MFCD00009146
Diethyl N-acetylaminomalonate
DIETHYL 2-ACETYLAMINOMALONATE
diethyl (acetylamino)propanedioate
UNII-4VDX81E00W
acetamido diethyl malonate
diethyl acetamido malonate
diethyl acetamido-malonate
Diethyl2-acetamidomalonate
diethyl-2-acetamidomalonate
2-ACETYLAMINO-MALONIC ACID DIETHYL ESTER
SCHEMBL81193
WLN: 2OVYVO2&MV1
CBDivE_002969
diethyl(n-acetylamino)malonate
diethyl 2-acetylamino-malonate
Diethyl a-(acetylamino)malonate
Diethyl 2-(acetylamino)malonate
Diethyl acetamidomalonate, 98%
CHEMBL3278808
SCHEMBL13410508
NSC7645
diethyl alpha-(acetamido)-malonate
Diethyl 2-(acetylamino)malonate #
BCP26461
HY-I1162
SDA87734
Acetamidomalonic acid, diethyl ester
BBL011570
CCG-45254
GEO-01032
STK802461
AKOS000120193
(Acetylamino)malonic acid diethyl ester
FD03031
NCGC00328362-01
11G-367S
BP-12339
SY001093
2-Acetylaminopropanedioic acid diethyl ester
DB-020343
A0015
CS-0011321
NS00023432
EN300-16887
2-(Acetylamino)propanedioic acid diethyl ester
AB00274777-04
SR-01000635034-1
Q27260567
Z56812731
F3098-5039