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Diethyl Isobutylmalonate

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Identification
Molecular formula
C13H24O4
CAS number
4130-67-2
IUPAC name
diethyl 2-isobutylpropanedioate
State
State

At room temperature, Diethyl Isobutylmalonate exists as a liquid. Due to its ester functional groups, it exhibits low water solubility but is soluble in organic solvents such as alcohols, ethers, and chloroform.

Melting point (Celsius)
-70.00
Melting point (Kelvin)
203.15
Boiling point (Celsius)
248.00
Boiling point (Kelvin)
521.15
General information
Molecular weight
216.28g/mol
Molar mass
216.2820g/mol
Density
0.9840g/cm3
Appearence

Diethyl Isobutylmalonate is a colorless liquid with a faint, pleasant odor. It is generally used as an intermediate in organic synthesis, particularly in pharmaceuticals and agrochemicals. The liquid is typically clear and can become slightly yellowish upon prolonged exposure to air and light.

Comment on solubility

Solubility of Diethyl 2-Isobutylpropanedioate

Diethyl 2-isobutylpropanedioate, a diester compound, exhibits unique solubility characteristics that are influenced by its structural properties. Understanding its solubility can be essential for various applications in organic chemistry and formulation science.

Solubility Characteristics:

  • Solvent Compatibility: This compound is known to be soluble in a variety of organic solvents such as ethanol, ether, and acetone, which allows it to be utilized in diverse formulations.
  • Water Solubility: Diethyl 2-isobutylpropanedioate has limited solubility in water due to its hydrophobic isobutyl component and its ester functional groups.
  • Temperature Dependency: Solubility may vary with temperature, with increased solubility often observed at elevated temperatures in organic solvents.

In general, esters like diethyl 2-isobutylpropanedioate tend to be more soluble in nonpolar or less polar solvents, making them particularly useful in applications where organic solvent use is warranted. As a rule of thumb, "like dissolves like" – thus, understanding the polarity of both the solute and solvent is crucial for predicting solubility.

Overall, the selective solubility profile of diethyl 2-isobutylpropanedioate underscores its versatility in various chemical processes.

Interesting facts

Interesting Facts About Diethyl 2-Isobutylpropanedioate

Diethyl 2-isobutylpropanedioate is a fascinating compound with various applications and properties that make it of interest to scientists and chemists alike. Here are some intriguing aspects of this compound:

  • Synthesis: This compound can be synthesized through the esterification of malonic acid with isobutyl alcohol, demonstrating a valuable reaction pathway in organic chemistry.
  • Applications: It is commonly used in the synthesis of various pharmaceuticals and agrochemicals, serving as an important intermediate in the production of more complex molecules.
  • Flavor and Fragrance: Due to its unique chemical structure, diethyl 2-isobutylpropanedioate may impart specific flavors and fragrances, making it useful in the food and cosmetic industries.
  • Versatility: The compound's versatility allows it to be utilized in a wide range of chemical reactions, showcasing its utility in both laboratory and industrial settings.
  • Safety Considerations: While working with diethyl 2-isobutylpropanedioate, safety protocols should be adhered to, as is the case with many organic compounds, to ensure safe handling and minimize health risks.

In conclusion, diethyl 2-isobutylpropanedioate represents a significant link in the chain of chemical synthesis, and its diverse applications in various industries underscore the important role such esters play in modern chemistry. As scientists continue to explore its uses, this compound may unveil even more secrets and applications, ultimately enriching our understanding of chemistry.

Synonyms
DIETHYL ISOBUTYLMALONATE
10203-58-4
Propanedioic acid, (2-methylpropyl)-, diethyl ester
Diethyl 2-isobutylmalonate
Propanedioic acid, 2-(2-methylpropyl)-, 1,3-diethyl ester
Malonic acid, isobutyl-, diethyl ester
EINECS 233-504-6
NSC 68522
AI3-05627
95WL9E8A77
1,3-diethyl 2-(2-methylpropyl)propanedioate
NSC-68522
DTXSID7064998
ETHYL 2-ETHOXYCARBONYL-4-METHYLVALERATE
DTXCID8032700
233-504-6
Isobutylmalonic acid diethyl ester
diethyl 2-(2-methylpropyl)propanedioate
MFCD00026869
2-isobutyl-malonic acid diethyl ester
Ethyl 2-carbethoxy-4-methyl pentanoate
2-(2-Methylpropyl)propanedioic Acid 1,3-Diethyl Ester; Isobutylmalonic Acid Diethyl Ester; (2-Methylpropyl)propanedioic Acid Diethyl Ester; 2-Isobutylmalonic Acid Diethyl Ester; Ethyl 2-Ethoxycarbonyl-4-methylvalerate; NSC 68522
diethyl i-butylmalonate
Ethyl isobutyl malonate
Diethyl-iso-butyl malonate
Diethyl 2-isobutylmalonate #
SCHEMBL335607
UNII-95WL9E8A77
OFRFGNSZCYDFOH-UHFFFAOYSA-
KAA20358
NSC68522
2-Isobutylmalonic acid diethyl ester
AC2239
AKOS005206830
CS-11401
SY019408
CS-0151883
I0251
NS00023104
EN300-28246
Ethyl 2-(ethoxycarbonyl)-4-(methyl)pentanoate
2-(ethyloxycarbonyl)-4-methylpentanoic acid, ethyl ester
Z254198236
InChI=1/C11H20O4/c1-5-14-10(12)9(7-8(3)4)11(13)15-6-2/h8-9H,5-7H2,1-4H3