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Phenoxybenzamine hydrochloride

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Identification
Molecular formula
C18H22ClNO
CAS number
63-92-3
IUPAC name
diethyl-[2-(N-phenoxycarbonylanilino)ethyl]ammonium;chloride
State
State

At room temperature, Phenoxybenzamine hydrochloride is typically a solid compound. It should be stored in a dry environment to maintain its integrity and prevent it from absorbing moisture.

Melting point (Celsius)
-24.00
Melting point (Kelvin)
249.15
Boiling point (Celsius)
244.00
Boiling point (Kelvin)
517.00
General information
Molecular weight
303.81g/mol
Molar mass
303.8050g/mol
Density
1.0921g/cm3
Appearence

Phenoxybenzamine hydrochloride typically appears as a white to off-white powder or crystalline solid. It is hygroscopic, meaning it can absorb moisture from the air, which may affect its appearance over time if not stored properly.

Comment on solubility

Solubility of Diethyl-[2-(N-phenoxycarbonylanilino)ethyl]ammonium Chloride

The solubility characteristics of diethyl-[2-(N-phenoxycarbonylanilino)ethyl]ammonium chloride can be understood through several key factors. Its solubility is influenced by both its ionic nature and the presence of the phenoxycarbonylanilino group. Here are some important points to consider:

  • Ionic Properties: As an ammonium salt, diethyl-[2-(N-phenoxycarbonylanilino)ethyl]ammonium chloride is likely to be soluble in water due to the positive charge of the ammonium ion and the presence of chloride as the counterion, which can help in dissociating the compound in an aqueous medium.
  • Hydrophobic Component: The phenoxycarbonylanilino moiety is relatively hydrophobic, potentially affecting overall solubility in polar solvents. This may lead to limited solubility in non-polar solvents, despite good solubility in polar solvents such as water.
  • Temperature Dependence: The solubility of salts like this compound can increase with temperature, making it important to consider solubility measurements at varied temperatures for precise applications.
  • pH Influence: The solubility might also be sensitive to changes in pH, as the ionization state of the ammonium group could change, affecting solubility levels in acidic or basic conditions.

In summary, while diethyl-[2-(N-phenoxycarbonylanilino)ethyl]ammonium chloride may exhibit good solubility in aqueous environments, its full solubility characteristics must be evaluated in relation to specific solvents, temperature, and pH conditions to fully understand its behavior in different chemical contexts.

Interesting facts

Interesting Facts about Diethyl-[2-(N-phenoxycarbonylanilino)ethyl]ammonium Chloride

Diethyl-[2-(N-phenoxycarbonylanilino)ethyl]ammonium chloride is a fascinating compound that bridges the realms of organic chemistry and medicinal applications. Here are some intriguing aspects of this compound:

  • Dual Functionality: This compound serves dual purposes as it is both a quaternary ammonium salt and an organo-functionalized derivative, showcasing characteristics that are beneficial in pharmaceutical development.
  • Structural Complexity: The compound features a complex structure that includes an aniline group, which is often associated with numerous biological activities, making it a compound of interest in drug design.
  • Potential Applications: Researchers are exploring its utility in various fields such as antimicrobial agents and anticancer therapies, given the significant activity linked with phenoxycarbonyl functionalities.
  • Stability and Reactivity: The quaternary ammonium component enhances not only the stability of the molecule but also its reactivity in biochemical environments, facilitating interactions with biological molecules.
  • Research Interest: Due to its distinctive structure, this compound could be a topic of interest in synthetic chemistry research, contributing to the advancement of synthetic methodologies.

As scientists continue to investigate compounds like diethyl-[2-(N-phenoxycarbonylanilino)ethyl]ammonium chloride, they unveil new potential applications and benefits that could impact various sectors, particularly in pharmaceuticals and material sciences. The exploration of such compounds exemplifies the endless possibilities within the chemical landscape!

Synonyms
Phenyl N-(2-diethylaminoethyl)carbanilate hydrochloride
N-Phenyl-N-(2-diethylaminoethyl)formic acid, phenyl ester hydrochloride
13658-91-8
NSC 92301
CARBANILIC ACID, N-(2-DIETHYLAMINOETHYL)-, PHENYL ESTER, HYDROCHLORIDE
Carbanilic acid, N-(2-(diethylamino)ethyl)-, phenyl ester, monohydrochloride