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Tolperisone hydrochloride

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Identification
Molecular formula
C16H24ClNO
CAS number
728-88-1
IUPAC name
diethyl-[2-(o-tolylcarbamoyloxy)cyclohexyl]ammonium;chloride
State
State

At room temperature, Tolperisone hydrochloride is in a solid state. It typically exists as a crystalline powder and is stable under normal conditions if kept dry and stored properly.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.20
Boiling point (Celsius)
286.80
Boiling point (Kelvin)
560.00
General information
Molecular weight
281.83g/mol
Molar mass
281.8490g/mol
Density
1.1099g/cm3
Appearence

Tolperisone hydrochloride appears as a white or off-white crystalline powder. It is odorless and has a bitter taste. It is typically supplied in a hygroscopic form, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of diethyl-[2-(o-tolylcarbamoyloxy)cyclohexyl]ammonium chloride

The solubility of diethyl-[2-(o-tolylcarbamoyloxy)cyclohexyl]ammonium chloride is greatly influenced by its chemical structure and the presence of functional groups.

Key Factors Affecting Solubility:

  • Polarity: The presence of a quaternary ammonium group in the compound increases its overall polarity, which generally enhances solubility in polar solvents.
  • Hydrophilic vs. Hydrophobic Regions: With both hydrophilic and hydrophobic portions in the molecular structure, the solubility can vary dramatically depending on the solvent used. This compound will likely be soluble in polar organic solvents.
  • Electrolytic Properties: As a chloride salt, it possesses ionic characteristics which can further increase solubility in aqueous solutions due to dissociation into its constituent ions.

In many cases, compounds of this nature exhibit greater solubility in organic solvents such as ethanol or methanol rather than water. This is often highlighted by quotes from solubility studies which note, “...the balance of hydrophilic and hydrophobic interactions determines the solubility profile.”

To summarize, while diethyl-[2-(o-tolylcarbamoyloxy)cyclohexyl]ammonium chloride shows excellent solubility in specific solvents, experimentation is crucial to determine the exact conditions under which optimal solubility can be achieved.

Interesting facts

Interesting Facts about Diethyl-[2-(o-tolylcarbamoyloxy)cyclohexyl]ammonium Chloride

Diethyl-[2-(o-tolylcarbamoyloxy)cyclohexyl]ammonium chloride is a fascinating compound with a multitude of applications and properties that make it noteworthy in the field of chemistry. Here are some engaging aspects to consider:

  • Versatile Applications: This compound is often explored in medicinal chemistry for its potential role as a drug delivery agent. Its unique structure allows it to interact effectively with biological systems.
  • Chemical Structure: The compound features a cyclohexyl group, which is known for its ability to provide rigidity and stability to molecular structures, enhancing pharmacological properties.
  • Functional Groups: The presence of the o-tolylcarbamoyloxy group is significant as it can improve solubility and bioavailability of the compound in various environments, making it a subject of research in related fields.
  • Ion Exchange Characteristics: As an ammonium salt, it possesses distinct ionic properties, which may facilitate interactions with anions and cations in solution, making it useful in various chemical processes.
  • Research Frontiers: With ongoing studies in organic synthesis, this compound can serve as a model system for understanding ion-pairing in organic solvents or during biological assays.

As noted by chemists in the field, “The exploration of compounds like diethyl-[2-(o-tolylcarbamoyloxy)cyclohexyl]ammonium chloride is crucial for advancing our understanding of molecular interactions.” This highlights the importance of such compounds in advancing both basic and applied sciences.

In summary, Diethyl-[2-(o-tolylcarbamoyloxy)cyclohexyl]ammonium chloride stands out not only due to its structural complexity but also its extensive applications in various branches of chemistry, especially in drug design and molecular biology.

Synonyms
o-Methylcarbanilic acid 2-(diethylamino)cyclohexyl ester hydrochloride
17095-90-8
K 1401
CARBANILIC ACID, o-METHYL-, 2-(DIETHYLAMINO)CYCLOHEXYL ESTER, HYDROCHLORIDE