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Quinacrine dihydrochloride

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Identification
Molecular formula
C23H30Cl2N4O3
CAS number
69-05-6
IUPAC name
diethyl-[3-[(1-nitroacridin-9-yl)ammonio]propyl]ammonium;dichloride
State
State

At room temperature, Quinacrine dihydrochloride is typically found in a solid state. Its bright yellow crystalline form is stable, and it does not readily evaporate or liquefy without significant heat.

Melting point (Celsius)
260.00
Melting point (Kelvin)
533.15
Boiling point (Celsius)
720.00
Boiling point (Kelvin)
993.15
General information
Molecular weight
508.82g/mol
Molar mass
508.8170g/mol
Density
1.3726g/cm3
Appearence

Quinacrine dihydrochloride typically appears as a bright yellow crystalline powder. It is often supplied in this form for pharmaceutical or laboratory use. The color makes it easy to identify, although care should be taken as its intense coloration can stain surfaces or fabrics.

Comment on solubility

Solubility of Diethyl-[3-[(1-nitroacridin-9-yl)ammonio]propyl]ammonium Dichloride

Diethyl-[3-[(1-nitroacridin-9-yl)ammonio]propyl]ammonium dichloride is a fascinating compound that showcases unique solubility characteristics. Its solubility can be examined through several important aspects:

  • Solvent Dependence: This compound's solubility is significantly influenced by the choice of solvent. It tends to dissolve well in polar solvents, such as water and methanol, due to its ionic nature.
  • Ionic Interactions: The presence of the dichloride anions allows for strong ionic interactions with similar polar solvents, enhancing its solubility.
  • Temperature Sensitivity: Solubility may also vary with temperature. Generally, an increase in temperature can lead to an increased solubility of ionic compounds, which may apply here as well.

In summary, the solubility profile of diethyl-[3-[(1-nitroacridin-9-yl)ammonio]propyl]ammonium dichloride is primarily governed by solvent characteristics and temperature variations. Understanding these traits is vital for applications in pharmaceutical and chemical processes where this compound may be utilized.

Interesting facts

Interesting Facts About Diethyl-[3-[(1-nitroacridin-9-yl)ammonio]propyl]ammonium Dichloride

Diethyl-[3-[(1-nitroacridin-9-yl)ammonio]propyl]ammonium dichloride is a fascinating compound that combines the properties of ammonium derivatives with the biological activity of nitroacridines. Below are some noteworthy points about this intriguing compound:

  • Structure with Purpose: The compound possesses a unique structural framework, incorporating both diethylammonium and nitroacridine components. This unique combination allows it to exhibit significant biological interactions, particularly in the context of medicinal chemistry.
  • Biological Relevance: Nitroacridine derivatives are known for their biological activities, including their roles as anti-cancer agents. This compound is being researched for its potential therapeutic applications in targeting cancer cells.
  • Mechanism of Action: The ammonium moiety in the compound may facilitate cellular uptake, making it more effective in targeting specific cells or tissues. Understanding its mechanism can pave the way for improved drug delivery systems.
  • Insight into Pharmacology: This compound is part of a larger class of compounds that highlight the importance of structure-activity relationships (SAR) in drug development. Scientists continuously study such relationships to enhance therapeutic efficacy and reduce side effects.
  • Dual Functionality: Its dual nature—combining both cationic properties from the ammonium group and the pharmacological effects of the nitroacridine—offers a platform for designing more complex therapeutic agents.

As research continues, diethyl-[3-[(1-nitroacridin-9-yl)ammonio]propyl]ammonium dichloride stands out not only for its chemical structure but also for its profound implications in the fields of pharmacology and medicinal chemistry. Its journey from a laboratory compound to a potential therapeutic agent is a testament to the evolving nature of chemical research.

Synonyms
17074-44-1
ACRIDINE, 9-((3-(DIETHYLAMINO)PROPYL)AMINO)-1-NITRO-, DIHYDROCHLORIDE
diethyl-[3-[(1-nitroacridin-9-yl)azaniumyl]propyl]azanium;dichloride
C 410 (Immunosuppressant)
1-Nitro-9-(diethylaminopropylamine)-acridine dihydrochloride
1-Nitro-9-(diethylaminopropylamino)-acridine-2 hydrochloride
1,3-Propanediamine, N,N-diethyl-N'-(1-nitro-9-acridinyl)-, dihydrochloride