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Nicergoline

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Identification
Molecular formula
C32H41N5O8
CAS number
27848-84-6
IUPAC name
diethyl-[3-[2-(2-furylmethyl)-3-(1-naphthyl)propanoyl]oxypropyl]ammonium;2-hydroxy-2-oxo-acetate
State
State

Nicergoline is typically in solid form at room temperature.

Melting point (Celsius)
136.00
Melting point (Kelvin)
409.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
649.72g/mol
Molar mass
649.7180g/mol
Density
1.3000g/cm3
Appearence

Nicergoline is a crystalline powder that is white to off-white in color. It may appear as a solid with a fine texture depending on the form in which it is manufactured.

Comment on solubility

Solubility of Diethyl-[3-[2-(2-Furylmethyl)-3-(1-naphthyl)propanoyl]oxypropyl]ammonium; 2-Hydroxy-2-Oxo-Acetate

The solubility of the compound diethyl-[3-[2-(2-furylmethyl)-3-(1-naphthyl)propanoyl]oxypropyl]ammonium; 2-hydroxy-2-oxo-acetate can be quite intriguing due to its complex structure. When analyzing the solubility characteristics of this compound, several factors come into play:

  • Polarity: The presence of ammonium groups generally suggests a higher polarity, which can enhance solubility in polar solvents like water.
  • Aromatic Systems: The inclusion of furyl and naphthyl groups can introduce hydrophobic interactions, potentially reducing solubility in water but increasing it in organic solvents.
  • Functional Groups: The carboxylate and hydroxyl groups present can significantly contribute to solubility in polar environments through hydrogen bonding.
  • Concentration: As with many compounds, solubility can be concentration-dependent; saturation limits should be considered when studying practical applications.

In summary, one might expect diethyl-[3-[2-(2-furylmethyl)-3-(1-naphthyl)propanoyl]oxypropyl]ammonium; 2-hydroxy-2-oxo-acetate to exhibit:

  • Good solubility in polar solvents.
  • Limited solubility in non-polar solvents.
  • Variable solubility based on temperature and concentration.

Overall, understanding the solubility of this compound requires a holistic view of its structural components and the environment in which it is being studied. Observations may vary, and experimentation is key to uncovering the precise solubility traits.

Interesting facts

Interesting Facts about Diethyl-[3-[2-(2-furylmethyl)-3-(1-naphthyl)propanoyl]oxypropyl]ammonium; 2-hydroxy-2-oxo-acetate

This complex organic compound features a rich structure that blends multiple functional groups, making it interesting from both a synthetic and pharmacological perspective. Here are some engaging facts about this compound that make it stand out:

  • Intriguing Functional Groups: The compound boasts a diethylammonium group, which is often found in biologically active molecules, hinting at potential pharmaceutical applications.
  • Furylmethyl and Naphthyl Motifs: The presence of a 2-furylmethyl group and a 1-naphthyl group suggests a possible affinity for biological targets, as these aromatic systems can enhance hydrophobic interactions with receptors.
  • Propanoyl Moiety: The propanoyl unit in the structure contributes to the overall polarity and potentially modulates the compound’s pharmacokinetics.
  • Biochemical Potential: Due to its distinct structure, this compound may exhibit interesting biological activities, such as anti-inflammatory or antitumor effects, which warrant further exploration.
  • Synthetic Versatility: The multiple functional groups make it a candidate for further derivatization, enabling chemists to design even more complex compounds for specific applications.

As a chemistry student or scientist, delving into the characteristics of this compound can lead to a deeper understanding of structure-activity relationships in medicinal chemistry. Research surrounding diethyl-[3-[2-(2-furylmethyl)-3-(1-naphthyl)propanoyl]oxypropyl]ammonium; 2-hydroxy-2-oxo-acetate could unveil new pathways for drug discovery, showcasing the beauty and complexity of organic chemistry.

Synonyms
2-Furanpropionic acid, alpha-(1-naphthylmethyl)-, 3-(diethylamino)propyl ester, oxalate (1:1)
alpha-(1-Naphthylmethyl)-2-furanpropionic acid 3-(diethylamino)propyl ester oxalate (1:1)
3406-49-3