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Nafarelin

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Identification
Molecular formula
C66H83N17O13
CAS number
76932-56-4
IUPAC name
dimethyl-[2-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]ammonium;2-hydroxy-2-oxo-acetate
State
State

At room temperature, nafarelin acetate is in a solid state. It is generally stable under normal conditions, though it's primarily used in pharmaceutical preparations rather than in its raw form.

Melting point (Celsius)
177.50
Melting point (Kelvin)
450.70
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
1220.45g/mol
Molar mass
1 220.4160g/mol
Density
1.2000g/cm3
Appearence

Nafarelin acetate typically appears as a white to off-white powder. Its physical state allows it to be processed into formulations for administration.

Comment on solubility

Solubility of Dimethyl-[2-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]ammonium;2-hydroxy-2-oxo-acetate

The solubility of the complex compound dimethyl-[2-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]ammonium;2-hydroxy-2-oxo-acetate can be influenced by multiple factors, including the molecular structure and the presence of functional groups. _Understanding the solubility behavior is essential for various applications, including drug formulation and chemical synthesis._

Key points about its solubility include:

  • Polar and Nonpolar Characteristics: The presence of the bulky naphthyl group may enhance hydrophobic interactions, potentially reducing solubility in polar solvents.
  • Functional Groups: The ammonium and acetate moieties tend to increase solubility in polar solvents like water, due to their ionic nature.
  • pH Dependency: The solubility could vary with pH changes, especially for the carboxylate group, making it crucial to consider the medium.

In summary, while the dual nature of this compound suggests it may have varying solubility properties, it likely exhibits greater solubility in polar solvents due to its ionic components. However, the bulky nonpolar constituents may limit its solubility in nonpolar environments. For specific applications or further analysis, empirical solubility testing is recommended to provide precise data.

Interesting facts

Interesting Facts about Dimethyl-[2-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]ammonium; 2-hydroxy-2-oxo-acetate

The compound named Dimethyl-[2-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]ammonium; 2-hydroxy-2-oxo-acetate is a fascinating hybrid molecule that intertwines various chemical functionalities. With its complex structure, it represents unique properties and potential applications.

Key Characteristics:

  • Structural Diversity: This compound integrates both a naphthyl group and a tetrahydrofuran moiety, showcasing a blend of aromatic and cyclic structures that enhance its chemical complexity.
  • Biological Relevance: Compounds containing sulfur and ammonium groups often exhibit interesting biological activities. The incorporation of these groups suggests potential pharmacological properties worth exploring.
  • Synthetic Potential: The careful design of this molecule can open doors for novel drug development strategies, utilizing its unique functional groups in medicinal chemistry.

In the realm of chemistry, the exploration of such compounds sheds light on the importance of structure-activity relationships. The presence of the naphthyl group may enhance its interaction with biological targets due to its hydrophobic nature, while the tetrahydrofuran component might provide additional flexibility.

As noted by chemists, "The beauty of chemistry lies in the ability to transform simple elements into complex structures that serve meaningful purposes." This compound perfectly exemplifies that philosophy, being a candidate for further research in both synthetic methods and biological evaluation.

By delving into the intricacies of compounds like this one, chemists can uncover new pathways for innovation in drug synthesis and development, highlighting the ever-evolving landscape of chemical science.

Synonyms
2-Furanpropanethiol, tetrahydro-S-(2-dimethylaminoethyl)-beta-(1-naphthyl)-, oxalate
15224-80-3
1-Naphthaleneethanethiol, S-(2-dimethylaminoethyl)-beta-(tetrahydrofurfuryl)-, oxalate
S-(2-Dimethylaminoethyl)-beta-(tetrahydrofurfuryl)-1-naphthaleneethanethiol oxalate