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Dimethyl-[2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium chloride

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Identification
Molecular formula
C18H30ClN3
CAS number
34911-55-2
IUPAC name
dimethyl-[2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium;chloride
State
State

This compound is a solid at room temperature.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
348.92g/mol
Molar mass
348.9200g/mol
Density
1.1500g/cm3
Appearence

The compound appears as a white to off-white crystalline powder or solid. It may be hygroscopic, absorbing moisture from the air.

Comment on solubility

Solubility of Dimethyl-[2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium Chloride

Dimethyl-[2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium chloride is an intriguing compound, particularly in the context of its solubility. Being a quaternary ammonium salt, it exhibits specific solubility characteristics influenced by its molecular structure.

Solubility Characteristics

The solubility of this compound can largely be attributed to the following factors:

  • Ionic Nature: As a chloride salt, it is likely to be soluble in polar solvents like water due to ion-dipole interactions.
  • Hydrophilicity: The presence of the pyrrolidine group and the benzimidazole moiety can enhance solubility in biological systems, making it potentially effective in pharmaceutical applications.
  • Chain Length: The length of the propyl and the dimethyl groups might hinder overall solubility in less polar solvents.

Thus, it is generally accepted that:

  • This compound is soluble in water because of its ionic nature and the presence of functional groups that can interact favorably with water molecules.
  • Its solubility may decrease significantly in non-polar solvents due to the lack of polarity in such environments.

In summary, the solubility of dimethyl-[2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium chloride is a reflection of its unique structural features, yielding favorable interactions with polar solvents while presenting challenges in non-polar media. This balance makes it a compound of interest for various applications in fields such as pharmacology and materials science.

Interesting facts

Interesting Facts about Dimethyl-[2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium Chloride

Dimethyl-[2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium chloride is a fascinating compound that belongs to the category of quaternary ammonium salts. Structural modifications of quaternary ammonium compounds lead to interesting biological and chemical properties. Here are some key points about this compound:

  • Biological Activity: Many quaternary ammonium compounds exhibit antimicrobial properties, making them useful in various applications, such as sanitizers and preservatives.
  • Applications in Pharmaceuticals: This compound features complex structural motifs, which may contribute to drug design. The pyrrolidine group can enhance interaction with biological targets, showing potential in therapeutic developments.
  • Solubility and Ionic Nature: As a chloride salt, it’s likely that this compound is highly soluble in polar solvents, which is beneficial for formulating drugs that are administered in liquid form.
  • Research and Development: The unique structural attributes of this compound open avenues for the synthesis of new derivatives, promoting ongoing research in medicinal and organic chemistry.
  • Significance of Benzimidazole Moiety: The benzimidazole structure has been recognized for its contribution to various biological activities, including anti-cancer and anti-inflammatory effects.

In summary, this compound encapsulates a rich tapestry of potential, from its roots in organic chemistry to its implications in health sciences. As noted by researchers, "The interplay of structure and function in molecular design can lead to revolutionary advancements in medicinal chemistry."
Therefore, the study of such compounds remains pivotal in continuing to unlock the mysteries of drug efficacy and safety.

Synonyms
Benzimidazole, 1-(2-(dimethylamino)-1-methylethyl)-2-(2-(pyrrolidin-1-yl)ethyl)-, hydrochloride
17817-90-2
1-(2-(Dimethylamino)-1-methylethyl)-2-(2-(pyrrolidin-1-yl)ethyl)benzimidazole hydrochloride