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Berberine

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Identification
Molecular formula
C20H18NO4
CAS number
2086-83-1
IUPAC name
dimethyl-[2-(2-tricyclo[10.4.0.03,8]hexadeca-1(16),3,5,7,12,14-hexaenyloxy)ethyl]ammonium;4-hydroxy-4-oxo-but-2-enoate
State
State

At room temperature, berberine is generally found in a solid state, primarily as a crystalline powder. It is stable under normal conditions and is insoluble in water but soluble in alcohols.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
336.36g/mol
Molar mass
336.3660g/mol
Density
1.3498g/cm3
Appearence

Berberine is typically a yellow crystalline powder. It is known for its bright yellow color, which has been used historically as a dye. The compound can also appear in a deep yellow to orange-yellow or as an amorphous powder, depending on the method of preparation and purification.

Comment on solubility

Solubility of Dimethyl-[2-(2-tricyclo[10.4.0.03,8]hexadeca-1(16),3,5,7,12,14-hexaenyloxy)ethyl]ammonium;4-hydroxy-4-oxo-but-2-enoate

The solubility of the compound dimethyl-[2-(2-tricyclo[10.4.0.03,8]hexadeca-1(16),3,5,7,12,14-hexaenyloxy)ethyl]ammonium;4-hydroxy-4-oxo-but-2-enoate can be influenced by several factors due to its complex structure. Here are some key aspects to consider:

  • Solvent Polarity: This compound includes both polar and nonpolar regions, which may affect its solubility in various solvents. It is likely to be more soluble in polar solvents like water than in nonpolar solvents.
  • Temperature: Increasing temperature can enhance the solubility of many organic compounds, possibly allowing for greater dissolution of this compound in suitable solvents.
  • Functional Groups: The presence of ammonium and hydroxyl groups suggests a degree of polarity, potentially leading to higher solubility in protic solvents.
  • Hydrogen Bonding: The ability of the compound to engage in hydrogen bonding may promote solubility in water, as these interactions can stabilize the compound in solution.
  • Concentration Effects: At higher concentrations, solubility may decrease due to saturation effects, impacting its overall usability in practical applications.

In summary, while it is challenging to predict the exact solubility behavior without empirical data, one can generally assert that the compound may demonstrate variable solubility influenced by its unique molecular architecture and the environment in which it is placed. As one researcher aptly noted, "Understanding the nuances of solubility is essential for mastering the behavior of chemical compounds."

Interesting facts

Interesting Facts about Dimethyl-[2-(2-tricyclo[10.4.0.03,8]hexadeca-1(16),3,5,7,12,14-hexaenyloxy)ethyl]ammonium; 4-hydroxy-4-oxo-but-2-enoate

This compound, with its intricate structure, is a fascinating example of organic synthesis and its applications in various fields. Here are some engaging facts about this unique chemical:

  • Complexity and Diversity: The compound showcases a blend of tricyclic structures and alkenes, demonstrating how complexity in a molecular structure can lead to diverse chemical properties.
  • Applications in Research: Compounds like this are often used in pharmaceutical research and material sciences due to their unique interactions and potential biological activities.
  • Quaternary Ammonium Compounds: As a quaternary ammonium compound, it has positively charged nitrogen, making it interesting for studies on cationic activity, which can enhance antimicrobial properties.
  • Potential Biological Activities: The presence of the hexaenyloxy moiety may contribute to biological significance, potentially impacting cellular processes or serving as a basis for drug development.
  • Analytical Chemistry: The detailed characterization techniques such as NMR (Nuclear Magnetic Resonance) and MS (Mass Spectrometry) are essential for studying such complex compounds, allowing chemists to understand their structure-function relationships better.

In summary, this compound represents the innovative edge of organic chemistry, with its potential implications extending from fundamental research to practical applications in various scientific domains. The combination of structural intricacies and potential functionalities makes it a subject of keen interest for chemists and researchers alike.