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Acrivastine

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Identification
Molecular formula
C22H30Cl2N3
CAS number
74066-08-1
IUPAC name
dimethyl-[2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylammonio)ethyl]ammonium;dichloride
State
State

At room temperature, acrivastine is typically in a solid state. It is stable under standard conditions and is used in its solid powdered form for pharmaceutical preparations.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.20
Boiling point (Celsius)
482.50
Boiling point (Kelvin)
755.50
General information
Molecular weight
478.46g/mol
Molar mass
478.4600g/mol
Density
1.0567g/cm3
Appearence

Acrivastine usually appears as a white to off-white powder. It is provided in a crystalline form and is often used in tablets or capsules for medicinal applications.

Comment on solubility

Solubility of Dimethyl-[2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylammonio)ethyl]ammonium;dichloride

The compound dimethyl-[2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylammonio)ethyl]ammonium;dichloride is known to exhibit distinct solubility characteristics that are influenced by its complex structure. Understanding its solubility is crucial for applications in medicinal chemistry and material science.

Solubility Characteristics:

  • Solvent Compatibility: This compound is generally more soluble in polar solvents, particularly water and ethanol, due to its ammonium group which promotes ionic interactions.
  • Temperature Influence: Increased temperature may enhance solubility; thus, it is often advisable to dissolve this compound at elevated temperatures when working in the lab.
  • pH Sensitivity: The solubility can be pH-dependent since changes in pH may affect the protonation state of the ammonium groups, altering the compound’s overall charge and solubility.

In conclusion, the solubility of dimethyl-[2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylammonio)ethyl]ammonium;dichloride is influenced by several factors, including the choice of solvent and environmental conditions. Recognizing these properties is key to effectively utilizing this compound in various applications.

Interesting facts

Interesting Facts about Dimethyl-[2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylammonio)ethyl]ammonium; Dichloride

Dimethyl-[2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylammonio)ethyl]ammonium; dichloride, commonly referred to in the scientific community with a shorthand nomenclature, presents intriguing characteristics that make it a subject of study in fields like medicinal chemistry and organic synthesis.

Notable Features of This Compound:

  • Unique Structure: The compound features a complex cyclic quinoline structure, which is known for its various biological activities, including antimicrobial and anticancer properties.
  • Potential Applications: Due to its molecular structure, it may exhibit properties valuable in pharmaceuticals, particularly against certain types of cancers that show sensitivity to quinoline derivatives.
  • Dual Functionality: The presence of both dimethylammonium and quinoline elements suggests potential uses in drug delivery systems and ionic liquids, which can exhibit unique solubility properties and reaction mechanisms.
  • Research Interest: Ongoing research is focusing on the ionic pairs formed with the dichloride component, investigating how they can enhance the solubility and bioavailability of active ingredients in drug formulations.

As a professional in the field may quote, "Understanding the chemistry of such complex molecules opens doors to innovative therapeutic strategies and novel compounds." This compound's intricate design not only challenges chemists but also offers promising avenues for breakthrough medical treatments.

Overall, the study of dimethyl-[2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylammonio)ethyl]ammonium; dichloride represents an exciting intersection of chemistry and medicine, with its potential yet to be fully unearthed.

Synonyms
18833-74-4
6H-Cyclohepta(b)quinoline, 11-((2-(diethylamino)ethyl)amino)-7,8,9,10-tetrahydro-, dihydrochloride
11-((2-(Dimethylamino)ethyl)amino)-7,8,9,10-tetrahydro-6H-cyclohepta(b)quinoline 2HCl
N'-(7,8,9,10-Tetrahydro-6H-cyclohepta(b)quinolin-11-yl)-N,N-dimethyl-1,2-ethanediamine 2HCl