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Acriflavine hydrochloride

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Identification
Molecular formula
C21H21Cl2N3O3
CAS number
8063-24-9
IUPAC name
dimethyl-[3-[(1-nitro-10-oxido-acridin-10-ium-9-yl)ammonio]propyl]ammonium;dichloride
State
State

At room temperature, Acriflavine hydrochloride is in a solid state. It is typically handled as a powder or crystalline solid.

Melting point (Celsius)
253.00
Melting point (Kelvin)
526.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
327.18g/mol
Molar mass
327.1780g/mol
Density
1.6800g/cm3
Appearence
The compound Acriflavine hydrochloride appears as an orange-red crystalline powder. It is known for its striking, vivid color.
Comment on solubility

Solubility of Dimethyl-[3-[(1-nitro-10-oxido-acridin-10-ium-9-yl)ammonio]propyl]ammonium Dichloride

The solubility of Dimethyl-[3-[(1-nitro-10-oxido-acridin-10-ium-9-yl)ammonio]propyl]ammonium dichloride can be viewed from several dimensions. This compound is part of a class of materials that typically demonstrate distinct solubility characteristics due to their ionic nature and structural properties.

Factors Influencing Solubility:

  • Ionic Interaction: Being an ammonium salt, it tends to dissolve well in polar solvents, particularly water, due to the formation of strong ionic interactions.
  • Hydrophilicity: The presence of charged groups enhances its affinity for water molecules, promoting solubility.
  • Chain Length: The propyl chain may have a slight hydrophobic influence, which can moderate the overall solubility compared to shorter or more branched alkyl chains.

As a general observation, compounds like this tend to exhibit high solubility in aqueous solutions, which is instrumental for bioavailability in pharmacological applications. However, temperature and pH can also significantly affect solubility, often decreasing in more acidic or basic conditions. Furthermore, solvent polarity plays a critical role; organic solvents with lower polarity may lead to reduced solubility.

In summary, the solubility of Dimethyl-[3-[(1-nitro-10-oxido-acridin-10-ium-9-yl)ammonio]propyl]ammonium dichloride is primarily dictated by its ionic structure and interactions with polar solvents, making it a highly soluble compound in suitable conditions.

Interesting facts

Interesting Facts about Dimethyl-[3-[(1-nitro-10-oxido-acridin-10-ium-9-yl)ammonio]propyl]ammonium Dichloride

This compound, known as dimethyl-[3-[(1-nitro-10-oxido-acridin-10-ium-9-yl)ammonio]propyl]ammonium dichloride, is an intriguing member of the family of ammonium salts. It combines the features of both organic and inorganic chemistry, offering a unique perspective on the behavior of cationic species in different environments.

Key Characteristics:

  • Cationic Nature: The compound is a quaternary ammonium salt, which means it carries a positive charge that makes it highly soluble in polar solvents.
  • Biological Activity: Compounds like this one often exhibit notable biological properties, including antimicrobial and anticancer activities, making them valuable in pharmaceutical development.
  • Functional Group Diversity: The presence of both nitro and acridine moieties contributes to its biological profile and can affect its reactivity and selectivity in chemical reactions.
  • Ion Exchange Potential: As a dichloride, it showcases interesting ion-exchange characteristics, which may be useful in a range of applications from drug delivery systems to water treatment technologies.

Applications of Interest:

  • Potential use in chemotherapy, given the known efficacy of acridine derivatives in cancer treatment.
  • Investigations into its role as a biosensor due to the electroactive nature of its components.
  • Study of its interactions with biological membranes could yield insights into drug design and delivery mechanisms.

In the words of chemists, "The complexity in the structure of this compound is mirrored in its potential applications, showcasing how intricate designs in chemistry can lead to groundbreaking solutions in medicine and material science."

This compound serves as a reminder of the importance of interdisciplinary approaches in chemistry, where organic, inorganic, and medicinal chemistry converge to push the boundaries of science and technology.

Synonyms
C-684
C 684
SN-24030
1-nitro-9-(dimethylaminopropylamino)acridine N-oxide
1-nitro-9-(3-dimethylaminopropylamino)acridine N-10-oxide
1,3-Propanediamine, N,N-dimethyl-N'-(1-nitro-9-acridinyl)-, N-oxide
20063-73-4
Nitracrine N-oxide
RefChem:917787
ACRIDINE, 9-((3-(DIMETHYLAMINO)PROPYL)AMINO)-1-NITRO-, N-OXIDE, DIHYDROCHLORIDE
20064-00-0
dimethyl-[3-[(1-nitro-10-oxidoacridin-10-ium-9-yl)azaniumyl]propyl]azanium;dichloride
NSC 295503
1-Nitro-9-(3-dimethylaminopropylamine)-acridine N-oxide dihydrochloride