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Tamsulosin hydrochloride

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Identification
Molecular formula
C20H28ClNO4S
CAS number
106133-20-4
IUPAC name
dimethyl-[3-(1-phenylisochroman-1-yl)propyl]ammonium;chloride
State
State
The compound is typically found in a solid state at room temperature, existing as a crystalline powder.
Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
383.50
Boiling point (Kelvin)
656.70
General information
Molecular weight
444.98g/mol
Molar mass
444.9770g/mol
Density
1.1890g/cm3
Appearence

Tamsulosin hydrochloride appears as a white or almost white crystalline powder. It is typically used in pharmaceutical formulations.

Comment on solubility

Solubility of Dimethyl-[3-(1-phenylisochroman-1-yl)propyl]ammonium Chloride

The solubility of dimethyl-[3-(1-phenylisochroman-1-yl)propyl]ammonium chloride (C20H28ClNO4S) can be influenced by various factors, including the presence of the chloride ion, which typically enhances solubility in polar solvents. Here are some key points to consider:

  • Influence of Ionic Nature: As an ammonium salt, the chloride component can significantly affect the solubility profile, making it more soluble in water compared to its neutral counterparts.
  • Polarity of the Compound: The large organic moiety contributes to a degree of hydrophobic character, potentially reducing solubility in purely polar solvents.
  • Common Solvents: It is likely soluble in:
    • Water
    • Alcohols (like ethanol and methanol)
    • Polar aprotic solvents (such as acetone)
  • Temperature Effects: Increasing temperature may improve solubility due to enhanced molecular motion and interaction.
  • pH Considerations: Being a quaternary ammonium compound could make its solubility sensitive to changes in pH, although it is generally stable across a wide pH range.

In summary, while dimethyl-[3-(1-phenylisochroman-1-yl)propyl]ammonium chloride suggests good solubility in aqueous environments, especially due to its ionic characteristics, the balance between its hydrophobic and hydrophilic components will ultimately dictate solubility in different solvents. This complexity is essential for predicting its behavior in various chemical and biological contexts.

Interesting facts

Interesting Facts About Dimethyl-[3-(1-phenylisochroman-1-yl)propyl]ammonium Chloride

Dimethyl-[3-(1-phenylisochroman-1-yl)propyl]ammonium chloride is a fascinating compound that blends organic chemistry with potential therapeutic applications. Here are some key points that stand out about this compound:

  • Hybrid Structure: This compound showcases a unique combination of dimethylammonium and a phenylisochroman moiety, suggesting a versatile structure that could interact with various biological targets.
  • Pharmacological Potential: The presence of the isochroman ring system often indicates potential biological activity. Compounds containing such rings have been studied for their effects on the central nervous system and might serve as lead compounds in developing new drugs.
  • Ion Exchange Properties: As a quaternary ammonium salt, it possesses distinct cationic properties, making it suitable for applications in ion exchange processes, potentially relevant in both environmental chemistry and materials science.
  • Relevance in Medicinal Chemistry: The phenyl group in the structure could afford the compound significant interaction with various pharmacological targets, making it a candidate for research in pain management or neurodegenerative diseases.
  • Synthetic Accessibility: The synthesis of related compounds often draws interest due to the relatively straightforward methods available for creating dimethylamines, which could prove advantageous in pharmaceutical applications.

In summary, the intriguing combination of dimethyl and phenylisochroman structures in this compound not only heightens its potential utility in medicinal chemistry but also opens avenues for further research into its biological implications. As stated by renowned chemists, "Exploring the myriad of interactions within complex molecules can unveil pathways to innovative treatments."

Exploring this compound further could lead to substantial advancements in our understanding of chemical interactions and their applications in health sciences.

Synonyms
1-ISOCHROMANPROPYLAMINE, N,N-DIMETHYL-1-PHENYL-, HYDROCHLORIDE
10565-82-9
LU 3-026
Isochroman, 1-(3-dimethylaminopropyl)-1-phenyl-, hydrochloride