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Propamidine Diisethionate

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Identification
Molecular formula
C13H20N4O2Cl2
CAS number
140-64-7
IUPAC name
dimethyl-[3-[2-(phenoxymethyl)-3H-benzimidazol-1-ium-1-yl]propyl]ammonium;dichloride
State
State

At room temperature, Propamidine Diisethionate is a solid compound.

Melting point (Celsius)
203.00
Melting point (Kelvin)
476.00
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.00
General information
Molecular weight
420.29g/mol
Molar mass
420.2920g/mol
Density
1.3000g/cm3
Appearence

Propamidine Diisethionate typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility Characteristics

The compound dimethyl-[3-[2-(phenoxymethyl)-3H-benzimidazol-1-ium-1-yl]propyl]ammonium;dichloride is known to exhibit interesting solubility properties, which can be influenced by various factors. Understanding its solubility is crucial for its application in various chemical processes.

Solubility in Water

This compound is likely to be soluble in water due to the presence of the ammonium group, which generally enhances solubility in polar solvents. The ionic dichloride component also contributes to:

  • Increased ion-dipole interactions
  • Greater interaction with water molecules

Organic Solvents

In organic solvents, the solubility can vary significantly. Its solubility is influenced mainly by the following:

  • Hydrophobic phenyl groups, which may lead to lower solubility in highly polar solvents.
  • Potential for increased solubility in solvents like dimethyl sulfoxide (DMSO) or ethanol due to favorable intermolecular interactions.

Thus, it may display moderate to good solubility in less polar organic solvents while remaining better soluble in more polar conditions.

Temperature Influence

Temperature may play a significant role in the solubility of this compound, with higher temperatures usually increasing solubility due to enhanced molecular motion, facilitating the dissolution process.

In summary, the solubility of dimethyl-[3-[2-(phenoxymethyl)-3H-benzimidazol-1-ium-1-yl]propyl]ammonium;dichloride is a complex interplay of ionic interactions, solvent polarity, and temperature effects, making it essential to consider these factors during experimentation and application.

Interesting facts

Interesting Facts about Dimethyl-[3-[2-(phenoxymethyl)-3H-benzimidazol-1-ium-1-yl]propyl]ammonium; Dichloride

Dimethyl-[3-[2-(phenoxymethyl)-3H-benzimidazol-1-ium-1-yl]propyl]ammonium; dichloride is a fascinating compound that holds a unique place in the study of chemistry and pharmacology. Below are some intriguing aspects of this compound:

  • Pharmacological Potential: The presence of the benzimidazolium moiety contributes significantly to the compound's potential as an active pharmaceutical ingredient. Benzimidazoles are known for their wide range of biological activities, including anti-parasitic and anti-cancer properties.
  • Cationic Properties: As a quaternary ammonium salt, this compound exhibits cationic behavior, which can enhance its ability to interact with biological membranes, making it particularly interesting for drug delivery and targeting applications.
  • Structural Complexity: The compound features a complex structure that includes both phenoxy and propyl groups, allowing for diverse interactions in biochemical systems. This complexity can contribute to varied biological activities and reactivities.
  • Research Applications: Researchers have been exploring this class of compounds for potential use in antimicrobial treatments. Given their structure, they may serve as effective agents against resistant bacterial strains.
  • Electrochemical Activity: Some studies suggest that compounds like this one may exhibit electroactive properties, making them candidates for development in fields such as organic electronics or sensors.
  • Comparative Studies: Scientists frequently compare this compound with structurally similar compounds to evaluate differences in activity. Such studies can yield insights into how subtle changes in molecular structure affect function.

In summary, dimethyl-[3-[2-(phenoxymethyl)-3H-benzimidazol-1-ium-1-yl]propyl]ammonium; dichloride is not merely a compound of interest due to its structural makeup, but also for its diverse applications, potential pharmaceutical benefits, and implications for future research.

Synonyms
1-(3-Dimethylaminopropyl)-2-(phenoxymethyl)benzimidazole dihydrochloride hydrate
Benzimidazole, 1-(3-(dimethylamino)propyl)-2-(phenoxymethyl)-, hydrochloride, hydrate (1:2:1)
20904-17-0
RefChem:325821