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Nitrendipine Hydrochloride

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Identification
Molecular formula
C20H28N5O2Cl
CAS number
91557-28-5
IUPAC name
dimethyl-[3-[5-nitro-2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium;chloride
State
State

At room temperature, dimethyl-[3-[5-nitro-2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium chloride is typically found in a solid state. It is stable under normal conditions and does not easily transition to a liquid or gaseous state without the application of significant heat.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.00
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.00
General information
Molecular weight
412.93g/mol
Molar mass
413.9200g/mol
Density
1.3250g/cm3
Appearence

Dimethyl-[3-[5-nitro-2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium chloride appears as a crystalline solid. The solid form is typically white to pale yellow, indicative of its pure state, with a granular texture. It is typically stored in airtight containers to prevent moisture absorption and degradation.

Comment on solubility

Solubility of Dimethyl-[3-[5-nitro-2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium Chloride

The compound Dimethyl-[3-[5-nitro-2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium chloride is a quaternary ammonium salt, which typically display unique solubility characteristics due to their ionic nature.

In general, the solubility of this compound can be affected by several factors:

  • Solvent Polarity: Ionic compounds usually show high solubility in polar solvents, particularly water. Therefore, one might expect that this compound would dissolve well in water.
  • Temperature: Increased temperature usually enhances the solubility of salts in water, potentially making the compound more soluble when heated.
  • Presence of Other Ions: The surrounding ionic environment can impact solubility; competing ions in the solution could lead to precipitation or increased solubility based on ionic interactions.

As a quaternary ammonium salt, Dimethyl-[3-[5-nitro-2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium chloride is expected to be quite soluble in water due to its charged nature, which forms favorable interactions with water molecules. However, empirical testing is crucial for confirming actual solubility levels under various conditions.

To summarize:

  • Highly soluble in polar solvents
  • Solubility may increase with temperature
  • Interactions with other ions can impact solubility

Overall, the solubility profile of this compound highlights important considerations for its application and further study in various chemical and biological environments.

Interesting facts

Interesting Facts about Dimethyl-[3-[5-nitro-2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium; Chloride

This fascinating compound belongs to a class of chemicals known as quaternary ammonium salts, which are well-known for their diverse applications in various fields, including pharmaceuticals, biochemistry, and chemical manufacturing. The unique structure of this compound, particularly the presence of a nitro group and a pyrrolidine moiety, contributes to its intriguing properties and potential biological activity.

Key Features:

  • Pharmaceutical Potential: Compounds like this one are often investigated for their efficacy as therapeutic agents. Incorporating a nitro group may enhance biological activity by affecting interactions with biological targets.
  • Versatile Applications: Quaternary ammonium compounds are used in a variety of settings, such as surfactants, disinfectants, and in synthesis as intermediates. This compound's versatile structure can lead to unique applications across different industries.
  • Structure-Activity Relationship: The presence of a 2-(2-pyrrolidin-1-ylethyl) fragment suggests interesting interactions with biological membranes and receptors, making it a subject of study in pharmacology for its potential to modulate biological activity.

As a scientist, one may also appreciate the meticulous design that goes into synthesizing such compounds. The challenge lies in optimizing both the efficacy and selectivity of the compound while minimizing potential side effects. This compound exemplifies how chemical entities can be tailored for specific applications, making the study of its properties both complex and rewarding.

In summary, Dimethyl-[3-[5-nitro-2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propyl]ammonium; Chloride represents more than just a chemical formula; it embodies a wealth of research opportunities and potential innovations in the realms of medicine and beyond.

Synonyms
Benzimidazole, 1-(3-dimethylaminopropyl)-5-nitro-2-(pyrrolidin-1-yl)ethyl-, hydrochloride
1-(3-Dimethylaminopropyl)-5-nitro-2-(pyrrolidin-1-yl)ethylbenzimidazole hydrochloride
17817-79-7