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Clomipramine

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Identification
Molecular formula
C19H23N2O4
CAS number
303-49-1
IUPAC name
dimethyl-[3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium;4-hydroxy-4-oxo-but-2-enoate
State
State

Clomipramine is typically found in a solid-state at room temperature. It is usually available in tablet form for pharmaceutical applications but exists as a crystalline powder in its pure chemical form.

Melting point (Celsius)
189.00
Melting point (Kelvin)
462.20
Boiling point (Celsius)
357.00
Boiling point (Kelvin)
630.20
General information
Molecular weight
314.85g/mol
Molar mass
314.8470g/mol
Density
1.2000g/cm3
Appearence

Clomipramine appears as a white to off-white crystalline powder. The compound is generally odorless and has a bitter taste. It is known to be photosensitive, meaning that it can degrade upon exposure to light, necessitating storage in light-protective containers.

Comment on solubility

Solubility of Dimethyl-[3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium;4-hydroxy-4-oxo-but-2-enoate

The solubility characteristics of the compound dimethyl-[3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium;4-hydroxy-4-oxo-but-2-enoate can be quite intricate due to its complex structure.

  • Ionization: The presence of ammonium in its structure suggests potential for ionization in aqueous solutions, which can enhance solubility.
  • Molecular Structure: The large aromatic system may introduce hydrophobic characteristics, possibly reducing solubility in polar solvents.
  • Functional Groups: The four hydroxy and keto groups can form hydrogen bonds, significantly influencing solubility properties.

In general, solubility can be assessed by considering the following:

  1. Polarity: Polar solvents like water may dissolve ionic or polar compounds better than nonpolar solvents.
  2. pH Influence: The solubility may vary with changes in pH, particularly for the ammonium group, which can interact with hydroxide ions.
  3. Temperature Effects: Higher temperatures can often increase solubility due to enhanced molecular motion.

As a result, the solubility of this compound is likely to depend on the solvent conditions, temperature, and specific interactions between the compound and solvent molecules.
Understanding these factors is crucial for applications in fields ranging from pharmaceuticals to materials science.

Interesting facts

Interesting Facts about Dimethyl-[3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium;4-hydroxy-4-oxo-but-2-enoate

This compound is a fascinating example of how diverse organic chemistry can be, especially in terms of complex molecular structures and potential biological applications. Here are some key points about this intriguing compound:

  • Structural Complexity: The presence of the benzothiepin moiety suggests potential therapeutic applications, as this structure has been found in many biologically active compounds. The ether linkage in the structure adds to its chemical richness.
  • Reactivity: The double bond and carbonyl groups in the 4-hydroxy-4-oxo-but-2-enoate portion lend themselves to various chemical reactions, making this compound a valuable intermediary in synthesis.
  • Biological Interest: Compounds containing similar structures have been known to exhibit anti-inflammatory, antimicrobial, and anticancer properties. Researchers continue to explore the potential pharmacological effects of this compound and its derivatives.
  • Versatility: This compound's diverse functional groups allow it to be modified for specific applications, including drug design or materials science, showcasing the versatility of organic compounds in modern chemistry.
  • Research Potential: Continued studies into its properties may reveal novel uses in biochemistry and medicinal chemistry, making it an exciting compound for future investigation.

In summary, dimethyl-[3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium;4-hydroxy-4-oxo-but-2-enoate combines intricate chemical architecture with promising biological implications, thus representing an essential area of study within the field of organic chemistry. It certainly piques the interest of both students and seasoned chemists alike!