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Cyclizine hydrochloride

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Identification
Molecular formula
C18H22Cl2N2O
CAS number
303-25-3
IUPAC name
dimethyl-[3-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-5-ium-11-yloxy)propyl]ammonium;dichloride
State
State
Cyclizine hydrochloride is typically in a solid state at room temperature, appearing as a crystalline powder.
Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
433.37g/mol
Molar mass
433.3710g/mol
Density
1.1800g/cm3
Appearence

Cyclizine hydrochloride typically appears as a white or almost white, crystalline powder. It is odorless and has a bitter taste. The crystals may appear as fine or granular depending on the preparation.

Comment on solubility

Solubility of Dimethyl-[3-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-5-ium-11-yloxy)propyl]ammonium; dichloride

The solubility characteristics of this compound can be intriguing, given its complex chemical structure. Here are key points to consider:

  • The presence of the dimethylammonium group often indicates that the compound may be soluble in polar solvents, particularly in water.
  • The dichloride nature of the compound suggests it may form a soluble ionic species in aqueous solutions.
  • However, the large cyclic structure present in the molecule, specifically the 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline moiety, can potentially hinder solubility due to steric effects and increased hydrophobicity.

In general, the solubility of this compound can be summarized as follows:

  1. Likely soluble in: Water, due to the ionic nature of the dichloride.
  2. Possibly soluble in: Other polar solvents like methanol and ethanol.
  3. Limited solubility in: Non-polar solvents like hexane or benzene, owing to its large hydrophobic components.

It is essential to consider factors like temperature, pH, and the presence of other solutes, which can significantly influence the solubility of this compound in various solvents.

Interesting facts

Interesting Facts about Dimethyl-[3-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-5-ium-11-yloxy)propyl]ammonium; Dichloride

Dimethyl-[3-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-5-ium-11-yloxy)propyl]ammonium; dichloride is a remarkable compound that belongs to a class of quaternary ammonium salts. Known for its unique structure and properties, this compound has captured the interest of researchers in various fields.

Key Aspects

  • Unique Structure: The compound features a tetrahydro-6H-cyclohepta[b]quinolinium moiety, which contributes to its potential biological activity. The cyclic structure often is associated with interesting electronic properties.
  • Applications in Chemistry: This compound serves as a valuable intermediate in the synthesis of other bioactive molecules. It highlights the importance of quaternary ammonium compounds in pharmaceutical chemistry.
  • Biological Significance: Compounds like this one are being studied for their potential roles in drug delivery systems, particularly due to their ability to interact with biological membranes.
  • Toxicity and Safety: Like many quaternary ammonium compounds, it is essential to understand the toxicity and environmental impact of this compound during laboratory work and application development.

As researchers continue to explore the intricate properties of dimethyl-[3-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-5-ium-11-yloxy)propyl]ammonium; dichloride, we may uncover new therapeutic possibilities that could lead to novel treatments in medicine. The study of such compounds emphasizes the importance of interdisciplinary research, bridging organic chemistry with pharmacology and materials science.

In conclusion, exploring compounds like this one opens doors to innovative solutions and applications, proving the vital role of chemistry in advancing technology and medicine.

Synonyms
6H-Cyclohepta(b)quinoline, 11-(3-(dimethylamino)propoxy)-7,8,9,10-tetrahydro-, dihydrochloride
11-(3-(Dimethylamino)propoxy)-7,8,9,10-tetrahydro-6H-cyclohepta(b)quinoline dihydrochloride
5231-39-0