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Amoxapine hydrochloride

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Identification
Molecular formula
C17H17ClN2O3
CAS number
31875-36-4
IUPAC name
dimethyl-[3-(8-nitro-6-oxo-benzo[b][1,4]benzoxazepin-5-yl)propyl]ammonium;chloride
State
State

Amoxapine hydrochloride is typically a solid at room temperature.

Melting point (Celsius)
160.30
Melting point (Kelvin)
433.45
Boiling point (Celsius)
320.30
Boiling point (Kelvin)
593.45
General information
Molecular weight
374.83g/mol
Molar mass
374.8310g/mol
Density
2.0974g/cm3
Appearence

Amoxapine hydrochloride is typically found as a white to off-white crystalline powder. It may be hygroscopic in nature, meaning it can absorb moisture from the environment.

Comment on solubility

Solubility of Dimethyl-[3-(8-nitro-6-oxo-benzo[b][1,4]benzoxazepin-5-yl)propyl]ammonium Chloride

Dimethyl-[3-(8-nitro-6-oxo-benzo[b][1,4]benzoxazepin-5-yl)propyl]ammonium chloride is a fascinating compound with unique solubility characteristics. Its solubility can be influenced by a variety of factors:

  • Polarity: The presence of the quaternary ammonium group tends to increase the compound's overall polarity, which typically enhances solubility in polar solvents.
  • Chloride Ion: The chloride ion can also contribute to solubility in water, as it is a highly soluble anion.
  • Temperature: The solubility may vary with temperature; generally, increased temperatures result in higher solubility for many compounds.
  • pH Levels: pH can play a significant role, especially in cases where the protonation state of the amine functional group may change, influencing solubility in different environments.

As a result, one might observe the following typical behavior:

  • Highly soluble in aqueous solutions due to its ionic nature.
  • Possible limited solubility in non-polar solvents.

In summary, **the solubility of Dimethyl-[3-(8-nitro-6-oxo-benzo[b][1,4]benzoxazepin-5-yl)propyl]ammonium chloride is most pronounced in polar solvents**, particularly water, largely due to the presence of the quaternary ammonium group and chloride ions. This characteristic can be crucial for its applications in various fields such as pharmaceuticals and materials science.

Interesting facts

Interesting Facts about Dimethyl-[3-(8-nitro-6-oxo-benzob[1,4]benzoxazepin-5-yl)propyl]ammonium; Chloride

Dimethyl-[3-(8-nitro-6-oxo-benzob[1,4]benzoxazepin-5-yl)propyl]ammonium; chloride is a fascinating compound that combines the principles of organic chemistry with intriguing biological applications. Here are some key points that highlight its significance:

  • Unique Structure: The compound's structure features a benzoxazepine ring, which is known for its diverse pharmacological activities, including antifungal and antibacterial properties.
  • Nitro Group Influence: The presence of the nitro group (–NO2), known for enhancing the reactivity of organics, often plays a crucial role in modifying the biological activity of compounds, making it a subject of interest for medicinal chemistry.
  • Ammonium Salt: As an ammonium salt derivative, this compound exhibits *ionic properties* that can enhance its solubility and efficacy in various biochemical environments, offering potential for pharmaceutical formulations.
  • Potential Uses: The unique combination of functional groups positions this compound for various applications in drug design, particularly in targeting specific biological pathways related to oxidative stress and inflammation.
  • Research Importance: Compounds like this are often used as *lead compounds* in the development of new therapeutic agents, making them critical in pharmaceutical research. They provide valuable insights into structure-activity relationships (SAR).

In light of the *growing interest* in medicinal chemistry and the pursuit of novel therapeutic agents, Dimethyl-[3-(8-nitro-6-oxo-benzob[1,4]benzoxazepin-5-yl)propyl]ammonium; chloride stands out as an essential compound. Its intricate structure and potential implications in biological systems make it a worthy subject of further exploration in scientific research.