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Betahistine

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Identification
Molecular formula
C21H28ClNO
CAS number
5638-76-6
IUPAC name
dimethyl-[4-oxo-4-[2-(2-phenylethyl)phenyl]butyl]ammonium;chloride
State
State

The compound is in a solid state at room temperature. It is usually found as a crystalline powder or colorless crystals and is hygroscopic, meaning it absorbs moisture from the air.

Melting point (Celsius)
229.80
Melting point (Kelvin)
502.90
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
327.90g/mol
Molar mass
327.8960g/mol
Density
1.0700g/cm3
Appearence

The compound typically appears as a white crystalline powder. It may also appear as colorless crystals. The compound is soluble in water and alcohol.

Comment on solubility

Solubility of Dimethyl-[4-oxo-4-[2-(2-phenylethyl)phenyl]butyl]ammonium Chloride

This intriguing compound, dimethyl-[4-oxo-4-[2-(2-phenylethyl)phenyl]butyl]ammonium chloride, exhibits some notable solubility characteristics relevant to its chemical structure. Here are some key points regarding its solubility:

  • Polar Nature: The quaternary ammonium component suggests a polar characteristic, which typically enhances solubility in polar solvents such as water.
  • Solvent Interactions: The presence of aromatic groups may impede solubility in non-polar solvents due to steric hindrance and weak intermolecular forces.
  • Chloride Ion Influence: The chloride ion may further stabilize the cationic form in aqueous solutions, promoting higher solubility.
  • Concentration Dependency: Solubility may vary significantly with temperature and concentration, warranting empirical assessment for precise applications.

In summary, while dimethyl-[4-oxo-4-[2-(2-phenylethyl)phenyl]butyl]ammonium chloride may show favorable solubility in polar solvents, its overall solubility profile is complex and dependent on multiple factors such as temperature and the presence of solvents. Understanding these attributes is crucial for its practical applications.

Interesting facts

Interesting Facts about Dimethyl-[4-oxo-4-[2-(2-phenylethyl)phenyl]butyl]ammonium Chloride

Dimethyl-[4-oxo-4-[2-(2-phenylethyl)phenyl]butyl]ammonium chloride is a fascinating compound that showcases the intersection of organic chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Complex Structure: The molecule features a unique dimethylammonium group that plays a crucial role in its chemical behavior and interaction with biological systems.
  • Pharmacological Potential: The compound is derived from a hybrid structure, suggesting potential applications in medicinal chemistry, particularly as a drug candidate aiming to target specific receptors.
  • Aromatic Interaction: The presence of the phenyl groups indicates a tendency for π-π stacking interactions, which could influence the compound’s solubility and biological activity.
  • Chloride Role: As a counterion, chloride could affect the stability and solubility of the compound in various solvents, making it an important factor in formulation chemistry.

The exploration of such compounds can lead to significant advancements in drug design and material science. As noted in the words of esteemed chemist, "The best way to predict the future is to invent it." Understanding the nuances of such compounds can certainly pave the way for innovative solutions in various fields.

This compound exemplifies how molecular complexity can lead to functional diversity, making it an exciting subject of study for chemists and students delving into the world of organic compounds.

Synonyms
4-(Dimethylamino)-2'-phenethylbutyrophenone hydrochloride
7428-73-1
2-(2-Phenylethyl)phenyl 3'-dimethylaminopropyl ketone hydrochloride
BUTYROPHENONE, 4-(DIMETHYLAMINO)-2'-PHENETHYL-, HYDROCHLORIDE
2-(2-Phenylaethyl)phenyl-3'-dimethylaminopropylketone hydrochlorid [German]
2-(2-Phenylaethyl)phenyl-3'-dimethylaminopropylketone hydrochlorid