Skip to main content

Diphenyl(2-piperidyl)methanol

ADVERTISEMENT
Identification
Molecular formula
C18H21NO
CAS number
770-05-8
IUPAC name
diphenyl(2-piperidyl)methanol
State
State

At room temperature, diphenyl(2-piperidyl)methanol is in a solid state.

Melting point (Celsius)
97.00
Melting point (Kelvin)
370.15
Boiling point (Celsius)
356.00
Boiling point (Kelvin)
629.15
General information
Molecular weight
265.37g/mol
Molar mass
265.3740g/mol
Density
1.1589g/cm3
Appearence

Diphenyl(2-piperidyl)methanol typically appears as a white crystalline powder. It may exhibit characteristic shimmering and is often utilized in various research and pharmaceutical applications.

Comment on solubility

Solubility of Diphenyl(2-piperidyl)methanol

Diphenyl(2-piperidyl)methanol, a compound characterized by its unique structure, exhibits some intriguing solubility properties. Here are key points to consider:

  • Solvent Affinity: This compound shows a good degree of solubility in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO).
  • Water Solubility: It tends to be less soluble in water compared to its solubility in organic solvents, due to the hydrophobic nature of the phenyl rings.
  • Temperature Influence: As with many organic compounds, increased temperatures may enhance solubility in organic solvents, making it easier to dissolve at higher temperatures.

When discussing solubility, it's essential to note that "like dissolves like." The larger phenyl and piperidine components of this compound typically lead to limited interaction with polar solvents, emphasizing its preference for nonpolar or less polar mediums.

To summarize:

  • Good solubility in organic solvents
  • Poor solubility in water
  • Temperature can affect the overall solubility

This specific solubility profile plays a crucial role in its applications, making it relevant for various organic synthesis processes and pharmaceutical formulations.

Interesting facts

Interesting Facts about Diphenyl(2-piperidyl)methanol

Diphenyl(2-piperidyl)methanol is a fascinating compound that is often explored in the realms of organic chemistry and medicinal chemistry due to its unique structure and potential applications. Here are some intriguing aspects of this compound:

  • Structural Diversity: This compound contains both phenyl and piperidine groups, which means it has the potential to engage in various chemical interactions, making it a useful building block in organic synthesis.
  • Pharmacological Potential: Compounds with piperidine moieties are prevalent in many pharmaceuticals. Researchers are interested in diphenyl(2-piperidyl)methanol for its possible biological activities, including its effects on the nervous system.
  • Chirality: The presence of a chiral center in this molecule presents opportunities for the development of enantiomerically pure compounds, which are often more effective or have fewer side effects in drug formulations.
  • Synthesis Pathways: The methods to synthesize this compound may involve various reactions, such as Friedel-Crafts alkylation or Mannich reactions, making it an excellent subject for studying reaction mechanisms.
  • Solvent Environment: The behavior of this compound can significantly change based on the solvent used during reactions, showcasing the importance of environmental factors in organic chemistry.

As noted by chemists in the field, “The study of complex molecules like diphenyl(2-piperidyl)methanol often leads to unexpected discoveries in pharmacology and materials science.” This underscores the compound's potential didactic value in educating students about the interplay between structure and function in chemistry.


Exploring diphenyl(2-piperidyl)methanol may also yield insights into the development of new therapies, especially as we continue to unlock the secrets of how molecular structures influence biological activity. Overall, it serves as a prime example of how chemistry can intersect with biology and medicine.

Synonyms
Pipradrol
Pyridrole
Pipralon
Piridrol
Pyridrol
Pipradol
alpha-Pipradol
Alertol
Gerodyl
467-60-7
Pipradrolo [DCIT]
Pipradrolum
Pipradrolo
Pipradrol [INN:BAN]
Pipradol [INN-Spanish]
Pipradrolum [INN-Latin]
diphenyl(piperidin-2-yl)methanol
MRD 108
alpha-(2-Piperidyl)benzhydrol
.alpha.-Pipradol
EINECS 207-394-5
UNII-S6I030E0DA
alpha,alpha-Diphenyl-alpha-(2-piperidyl)methanol
BRN 0229537
S6I030E0DA
Gerodil (Salt/Mix)
alpha,alpha-Diphenyl-2-piperidinemethanol
Meratran (Salt/Mix)
.alpha.-(2-Piperidyl)benzhydrol
HSDB 8016
Leptidrol (Salt/Mix)
MRD-108
PIPRADROL [INN]
PIPRADROL [MI]
2-Piperidinemethanol, .alpha.,.alpha.-diphenyl-
PIPRADROL [WHO-DD]
DTXSID2023486
alpha-(2-Piperidyl)-benzohydrol
.alpha.,.alpha.-Diphenyl-2-piperidinemethanol
2-PIPERIDINEMETHANOL, alpha,alpha-DIPHENYL-
5-21-04-00070 (Beilstein Handbook Reference)
.alpha.,.alpha.-Diphenyl-.alpha.-(2-piperidyl)methanol
Pipradol (INN-Spanish)
Pipradrolum (INN-Latin)
.ALPHA.-(2-PIPERIDYL)BENZHYDRYL ALCOHOL
alpha-Pipradrol
DTXCID903486
N06BX15
alpha-(2-piperidyl)benzhydryl alcohol
207-394-5
(+-)-.alpha.,.alpha.-diphenyl-.alpha.-(2-piperidinyl)methanol
(+-)-alpha,alpha-diphenyl-alpha-(2-piperidinyl)methanol
xswhnygmwwvaie-uhfffaoysa-n
(+/-)-.ALPHA.,.ALPHA.-DIPHENYL-.ALPHA.-(2-PIPERIDINYL)METHANOL
DEA No. 1750
Oprea1_717873
SCHEMBL156360
CHEMBL2110938
CHEBI:135101
Diphenyl(2-piperidinyl)methanol #
STL508163
AKOS015995614
DB11584
NS00017974
Q2084598
(+/-)-ALPHA,ALPHA-DIPHENYL-ALPHA-(2-PIPERIDINYL)METHANOL