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Diphenyl(4-piperidyl)methanol

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Identification
Molecular formula
C18H21NO
CAS number
770-97-8
IUPAC name
diphenyl(4-piperidyl)methanol
State
State

At room temperature, Diphenyl(4-piperidyl)methanol is typically in a solid state.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
524.00
Boiling point (Kelvin)
797.15
General information
Molecular weight
265.37g/mol
Molar mass
265.3720g/mol
Density
1.1211g/cm3
Appearence

Diphenyl(4-piperidyl)methanol typically appears as a white to off-white crystalline powder, which may have a faint characteristic odor.

Comment on solubility

Solubility of Diphenyl(4-piperidyl)methanol

Diphenyl(4-piperidyl)methanol, with its complex structure, exhibits unique solubility properties that are worth discussing. The solubility of chemical compounds is influenced by various factors, and here are some key points to consider:

  • Polarity: The presence of multiple aromatic rings and a piperidyl group affects the overall polarity of the compound. These features generally lead to higher solubility in organic solvents, particularly in nonpolar solvents.
  • Hydrogen Bonding: The hydroxyl group (-OH) in diphenyl(4-piperidyl)methanol can engage in hydrogen bonding, allowing it to exhibit some degree of solubility in polar solvents like water. However, this property may not be strong enough to result in high solubility.
  • Temperature Dependence: As with many organic compounds, solubility can vary significantly with temperature. Increased temperatures often enhance solubility in organic solvents.
  • Concentration Effects: At higher concentrations, the rate of solubility may decrease due to saturation, leading to separation phases.

Overall, while diphenyl(4-piperidyl)methanol demonstrates potential solubility in both polar and nonpolar environments, it is crucial to consider specific conditions, such as solvent choice and temperature, for optimal solubility. As one notable quote states, "The solubility of a compound can often reveal as much about its structure as its reactivity."

Interesting facts

Interesting Facts about Diphenyl(4-piperidyl)methanol

Diphenyl(4-piperidyl)methanol is a fascinating organic compound that has garnered interest due to its unique structure and potential applications in medicinal chemistry. Here are some noteworthy points about this compound:

  • Structure and Composition: This compound features a central carbon atom attached to two phenyl groups and a piperidine ring, contributing to its complexity and chemical uniqueness.
  • Potential Applications: Due to its structural characteristics, diphenyl(4-piperidyl)methanol is being explored for its possible role as a pharmacological agent, particularly in the realm of neurological research.
  • Synergistic Effects: The combination of the diphenyl and piperidinyl groups can lead to interesting interactions in biological systems, making it a compound of interest for drug design and development.
  • Analytical Chemistry: Researchers often use this compound in studies involving drug stability and formulation, as it can act as a model compound for understanding the behavior of similar molecules.
  • Research Opportunities: The compound’s unique properties open avenues for further studies that could lead to novel therapeutic pathways or a deeper understanding of its mechanisms.

In summary, diphenyl(4-piperidyl)methanol is not just another simple organic compound; its intricate structure and potential applicability make it a noteworthy subject for researchers and chemists alike. As one scholar aptly stated, "Understanding the nuances of such compounds can unlock new frontiers in medicinal science."

Synonyms
Azacyclonol
diphenyl(piperidin-4-yl)methanol
Frenquel
alpha-(4-Piperidyl)benzhydrol
gamma-Pipradol
4-Piperidinemethanol, alpha,alpha-diphenyl-
alpha,alpha-Diphenyl-4-piperidinemethanol
Ataractan
Calmeran
Azaciclonolo
Azacyclonolum
Azacyklonol
Frenoton
Psychosan
Azaciclonolo [DCIT]
Diphenyl-4-piperidylmethanol
MER 17
Azacyclonol [INN:BAN]
Azacyclonolum [INN-Latin]
azaciclonol
UNII-2MMR990PEM
.gamma.-Pipradol
EINECS 204-092-5
2MMR990PEM
BRN 0230221
DTXSID2045280
4-(Diphenylhydroxymethyl)piperidine
AZACYCLONOL [MI]
AZACYCLONOL [INN]
AZACYCLONOL [WHO-DD]
DTXCID0025280
.alpha.-(4-Piperidyl)benzhydrol
EC 204-092-5
4-Piperidinemethanol, .alpha.,.alpha.-diphenyl-
5-21-04-00072 (Beilstein Handbook Reference)
TERFENADINE IMPURITY I [EP IMPURITY]
.alpha.,.alpha.-Diphenyl-4-piperidinemethanol
Azacyclonolum (INN-Latin)
TERFENADINE IMPURITY I (EP IMPURITY)
204-092-5
zmisodwvfhhwnr-uhfffaoysa-n
115-46-8
alpha,alpha-diphenyl-4-piperidinomethanol
Diphenyl(4-piperidinyl)methanol
Diphenyl-piperidin-4-yl-methanol
MFCD00066980
a-(4-Piperidyl)benzhydrol
MLS000558844
CHEMBL127508
NCGC00016366-01
CAS-115-46-8
SMR000149160
Diphenyl(piperidin-4-yl)methanol (Azacyclonol)
Prestwick_84
Maybridge3_001033
Opera_ID_1183
Prestwick0_000093
Prestwick1_000093
Prestwick2_000093
Prestwick3_000093
TERFENADINE_met007
|A-(4-Piperidyl)benzhydrol
Azacyclonol (MDL 4829)
Oprea1_114075
Oprea1_848733
BSPBio_000046
diphenyl 4-piperidyl carbinol
MLS001201777
SCHEMBL241817
SPBio_001985
BPBio1_000052
CHEBI:93706
Diphenyl(4-piperidinyl)methanol #
HMS1433O21
HMS1568C08
HMS2095C08
HMS2230G14
HMS3652K11
HMS3712C08
HMS3885E13
4-(hydroxydiphenylmethyl)piperidine
HY-B0530
4-(diphenylhydroxymethyl) piperidine
Tox21_110399
AC2248
BBL010986
BDBM50017724
CCG-51239
s3196
STK802108
4-[Hydroxy(diphenyl)methyl]piperidine
AKOS000121583
Tox21_110399_1
4-(hydroxy-diphenyl-methyl)-piperidine
AC-2127
4-Piperidinemethanol, |A,|A-diphenyl-
IDI1_012420
NCGC00016366-02
NCGC00016366-04
NCGC00179677-01
AS-13114
FA160305
SY036924
alpha, alpha-diphenyl-4-piperidinemethanol
alpha,alpha -diphenyl-4-piperidinemethanol
alpha,alpha -diphenyl-4-piperidine-methanol
DB-041270
NS00003707
P1369
SW196396-3
EN300-17628
SR-01000640550
Q4832014
SR-01000640550-1
SR-01000640550-4
BRD-K97061094-001-03-2
BRD-K97061094-001-20-6
BRD-K97061094-001-21-4
Z56969317
Azacyclonol (alpha,alpha-Diphenyl-4-piperidinomethanol)
FEXOFENADINE HYDROCHLORIDE IMPURITY E [EP IMPURITY]
|A inverted exclamation mark,|A inverted exclamation mark-Diphenyl-4-piperidinemethanol