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Diphenylpyrilin

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Identification
Molecular formula
C18H21NO · HCl
CAS number
770-66-9
IUPAC name
diphenyl(4-piperidyl)methanol;hydrochloride
State
State
The compound is solid at room temperature.
Melting point (Celsius)
191.00
Melting point (Kelvin)
464.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
299.85g/mol
Molar mass
299.8450g/mol
Density
1.2100g/cm3
Appearence
Diphenyl(4-piperidyl)methanol hydrochloride appears as a white to off-white crystalline powder.
Comment on solubility

Solubility of Diphenyl(4-piperidyl)methanol Hydrochloride

The solubility of diphenyl(4-piperidyl)methanol hydrochloride is an important characteristic that influences its application in various fields, particularly in pharmaceuticals. Understanding its solubility can help determine the compound's behavior in biological systems and its effectiveness as a therapeutic agent.

Key Points about Solubility

  • Polar versus Non-Polar: Due to the presence of a hydrochloride moiety, this compound is likely to exhibit high solubility in polar solvents, such as water. The ionic nature of the hydrochloride enhances its dissolvability.
  • Impact of Temperature: Like many organic compounds, the solubility of diphenyl(4-piperidyl)methanol hydrochloride may increase with temperature. Solutions may become more concentrated as thermal energy reduces the intermolecular forces holding particles together.
  • pH Dependence: The solubility may also be affected by the pH of the solution, as alterations in the protonation state can influence the compound's ionic character. Queries regarding its solubility might benefit from exploring the compound's behavior across a range of pH levels.
  • Comparison with Similar Compounds: In comparison to other piperidine derivatives, this compound might demonstrate varying solubility profiles based on structural differences that affect hydrogen bonding and dipole interactions.

In conclusion, diphenyl(4-piperidyl)methanol hydrochloride is expected to be soluble in aqueous solutions, enabling its practical use in medicinal formulations. However, specific solubility data should be verified experimentally, particularly for applications that require precise measurements.

Interesting facts

Interesting Facts about Diphenyl(4-piperidyl)methanol Hydrochloride

Diphenyl(4-piperidyl)methanol hydrochloride, often referred to within the field for its complex structure, showcases several noteworthy attributes that make it a compound of interest among chemists.

Applications and Uses

  • Pharmaceutical Relevance: This compound is primarily recognized for its role in medicinal chemistry, acting as a precursor in the synthesis of various pharmaceutical agents.
  • Research Tool: It serves as a valuable tool for exploring the mechanisms of action in neuropharmacology and can affect neurotransmitter systems.
  • Potential Treatments: Its derivatives have been investigated for potential therapeutic applications, particularly in managing conditions such as anxiety and depression.

Synthesis and Properties

Through a series of specific chemical reactions, diphenyl(4-piperidyl)methanol hydrochloride can be synthesized, allowing for its study and application. Chemists have noted its unique properties that open doors for various modifications:

  • It features a piperidine ring, known for its basicity and ability to participate in significant biological interactions.
  • The diphenyl structure contributes to the compound's stability and makes it an alluring subject for studies in organic synthesis.

Chemical Structure Significance

The balanced composition of this compound highlights important aspects of molecular design:

  • Structural Versatility: The presence of the two phenyl groups provides ample opportunities for substitution, leading to a variety of derivatives.
  • Biological Activity: The configuration allows for interactions with biological receptors, making it an essential subject in pharmacological research.

"The beauty of chemistry lies in the ability to design and tailor compounds for specific biological outcomes," notes a respected chemist in the field. This sentiment rings particularly true for diphenyl(4-piperidyl)methanol hydrochloride, as each modification can lead to new discoveries and innovations.

Overall, the exploration of diphenyl(4-piperidyl)methanol hydrochloride around its synthesis, applications, and properties continues to unveil possibilities in both industrial and research realms.

Synonyms
1798-50-1
AZACYCLONOL HYDROCHLORIDE
Azacyclonol HCl
Frenquel hydrochloride
Azacyclonol, hydrochloride
gamma-Pipradol hydrochloride
Azacyclonol hydrochloride [NF]
4BXX0XNP9R
EINECS 217-284-9
alpha-(4-Piperidyl)benzhydrol hydrochloride
4-Piperidinemethanol, alpha,alpha-diphenyl-, hydrochloride
alpha,alpha-Diphenyl-4-piperidinemethanol hydrochloride
DTXSID90170867
EC 217-284-9
AZACYCLONOL HYDROCHLORIDE [MI]
AZACYCLONOL HYDROCHLORIDE [MART.]
AZACYCLONOL HYDROCHLORIDE [WHO-DD]
4-Piperidinemethanol, alpha,alpha-diphenyl-, hydrochloride (1:1)
ALPHA.,.ALPHA.-DIPHENYL-4-PIPERIDINEMETHANOL, HYDROCHLORIDE
AZACYCLONOL HYDROCHLORIDE (MART.)
DTXCID4093358
ALPHA.,ALPHA-DIPHENYL-4-PIPERIDINEMETHANOL, HYDROCHLORIDE
diphenyl(piperidin-4-yl)methanol hydrochloride
Diphenyl-piperidin-4-yl-methanol hydrochloride
Azacyclonol (hydrochloride)
UNII-4BXX0XNP9R
MFCD00039039
alpha,alpha-Diphenylpiperidine-4-methanol hydrochloride
diphenyl(piperidin-4-yl)methanol,hydrochloride
diphenyl(piperidin-4-yl)methanol;hydrochloride
CHEMBL2105900
LBRAWKGGVUCSOX-UHFFFAOYSA-N
AKOS015844351
AC-13537
DB-044378
NS00078201
Alpha,alpha-diphenyl-4-piperidinomethanol hydrochloride
Q27259389
alpha,alpha -diphenyl-4-piperidinemethanol hydrochloride