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Fluorometholone phosphate

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Identification
Molecular formula
C22H28FO8P
CAS number
426-13-1
IUPAC name
dipotassium;[2-[(2S,4R,8S,11S,12R)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxo-ethyl] phosphate
State
State

At room temperature, the compound is in a solid state.

Melting point (Celsius)
208.30
Melting point (Kelvin)
481.45
Boiling point (Celsius)
307.30
Boiling point (Kelvin)
580.45
General information
Molecular weight
538.54g/mol
Molar mass
538.5360g/mol
Density
2.0100g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of Dipotassium [2-[(2S,4R,8S,11S,12R)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxo-ethyl] phosphate

The solubility of dipotassium [2-[(2S,4R,8S,11S,12R)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxo-ethyl] phosphate is influenced by several critical factors:

  • Polarity: The presence of phosphate groups typically enhances solubility in polar solvents like water, making the compound more soluble in aqueous environments.
  • Charge: Being a dipotassium salt, the cationic nature contributes to solubility, particularly in ionic and polar media.
  • Temperature: As with many chemical compounds, increased temperature can often lead to increased solubility in certain solvents.
  • pH levels: The solubility may vary depending on the acidity or basicity of the solution, which can affect the ionization state of the compound.

As stated, "Like dissolves like," meaning that the structural characteristics of dipotassium phosphate make it more likely to dissolve in similar types of solvents. Given its complex structure, solubility can also be affected by the presence of other solutes or factors in the solution. Regular testing and analysis are essential to accurately predict its solubility under varying conditions.

In summary, dipotassium phosphate displays essential attributes that generally favor its solubility in aqueous solutions yet remains subject to the influences of temperature, pH, and solvent characteristics.

Interesting facts

Interesting Facts about Dipotassium [2-[(2S,4R,8S,11S,12R)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxo-ethyl] Phosphate

Dipotassium [2-[(2S,4R,8S,11S,12R)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxo-ethyl] phosphate is a remarkable compound, brimming with intriguing properties and potential applications. Here are some noteworthy aspects:

  • Unique Structure: This compound features an intricate multi-ring structure, commonly referred to as a pentacyclic system, which is essential for its biological activity.
  • Bioactivity: It is often studied for its role in various biological systems, showcasing properties that may influence metabolic pathways.
  • Phosphorylation: The phosphate group plays a crucial role in many biochemical reactions, acting as a signaling molecule in cellular processes.
  • Fluorine Substitution: The presence of a fluorine atom not only enhances the compound's stability but also impacts its interactions with biological targets.
  • Potential Applications: Given its complex composition, research explores its potential in pharmaceuticals, particularly in developing inhibitors or modulators for various enzymes.

"The novel structures in organic chemistry not only challenge our understanding but also redefine potential pathways for drug discovery."

As a compound representative of modern chemistry, dipotassium [2-[(2S,4R,8S,11S,12R)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxo-ethyl] phosphate invites continued research and exploration in the realms of medicinal chemistry and biochemistry. Its sophisticated architecture underscores the beauty and complexity of chemical compounds.