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Flumazenil Dipotassium Salt

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Identification
Molecular formula
C15H12ClFN3O3
CAS number
62189-74-0
IUPAC name
dipotassium;7-nitro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate;hydroxide
State
State

At room temperature, flumazenil dipotassium salt is typically in a solid state, specifically as a powder. It is stable under normal conditions of temperature and pressure.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
448.58g/mol
Molar mass
448.5810g/mol
Density
1.3000g/cm3
Appearence

Flumazenil dipotassium salt typically appears as a white or almost white powder. Its crystalline form may vary, but it is commonly available as a fine powder, suitable for laboratory and pharmaceutical use.

Comment on solubility

Solubility of Dipotassium 7-Nitro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate Hydroxide

The solubility of dipotassium 7-nitro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate hydroxide is influenced by several factors, which can be summarized as follows:

  • Polarity: The presence of polar carboxylate groups in the molecule generally enhances solubility in polar solvents, such as water.
  • Ionic Nature: As a dipotassium salt, it may exhibit enhanced solubility due to the ionic interactions with solvent molecules.
  • pH Dependence: The solubility of the compound can vary with pH; it is likely to be more soluble in basic solutions due to the favorable interaction with hydroxide ions.
  • Temperature: Increased temperature typically leads to higher solubility in most cases, so this compound may also follow that trend.

In conclusion, the solubility of this compound is expected to be significantly influenced by its ionic nature and the functional groups present. Therefore, it is crucial to consider solvents and environmental conditions when assessing its solubility. As a general statement, compounds with carboxylate functionalities are often more soluble than those without; hence, “the molecular structure dictates the solubility behavior.”

Interesting facts

Interesting Facts about Dipotassium 7-Nitro-2-Oxo-5-Phenyl-1,3-Dihydro-1,4-Benzodiazepine-3-Carboxylate Hydroxide

Dipotassium 7-Nitro-2-Oxo-5-Phenyl-1,3-Dihydro-1,4-Benzodiazepine-3-Carboxylate Hydroxide is a fascinating compound that falls under the category of benzodiazepines, which are known for their psychoactive properties. Here are some intriguing aspects:

  • Pharmacological Significance: Like many benzodiazepines, this compound potentially exhibits a variety of biological activities, such as anxiolytic (anti-anxiety), sedative, and muscle relaxant effects, making it important in pharmaceutical research.
  • Structure-Activity Relationship: The structural features of this compound, particularly the nitro and phenyl groups, play a crucial role in its activity. Understanding the relationship between its structure and biological effect is a key area of study in medicinal chemistry.
  • Synthesis and Modification: Researchers are actively investigating ways to synthesize and modify this compound to enhance its efficacy and reduce side effects, which is a common practice in drug development.
  • Potential Applications: Beyond its possible use in treating anxiety and related disorders, this compound might present opportunities in developing new therapies for conditions like epilepsy and sleep disorders.
  • Dynamic Research Field: The ongoing research around this compound contributes to the broader understanding of benzodiazepines and their effects on the central nervous system, creating a dynamic field for both chemists and medical scientists.

As one delves deeper into the complexities of dipotassium 7-nitro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate hydroxide, it becomes clear that its study is not just about the compound itself but also about its potential impact on human health and therapeutic advancements. As noted by many in the field: “Understanding these compounds can unlock new avenues for treatment.”

Synonyms
24477-47-2
DTXSID10947371
Potassium 7-nitro-2-oxido-5-phenyl-3H-1,4-benzodiazepine-3-carboxylate--water (2/1/1)
RefChem:1096526
DTXCID301375631
4335 CB
SCHEMBL31518755
dipotassium;7-nitro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate;hydroxide