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Hydrocortisone sodium phosphate

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Identification
Molecular formula
C21H29Na2O8P
CAS number
121-26-6
IUPAC name
disodium;[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] phosphate
State
State

At room temperature, hydrocortisone sodium phosphate is a solid.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
804.00
Boiling point (Kelvin)
1 077.15
General information
Molecular weight
484.40g/mol
Molar mass
484.3960g/mol
Density
1.4500g/cm3
Appearence

Hydrocortisone sodium phosphate appears as a white or almost white crystalline powder. It is generally available in solid form for pharmaceutical applications.

Comment on solubility

Solubility of Disodium [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] Phosphate

The solubility of disodium [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] phosphate can be quite intricate due to its complex structure. However, some key points can be noted regarding its solubility:

  • Nature of Solubility: As a phosphate derivative, this compound exhibits notable solubility characteristics primarily in polar solvents.
  • Influencing Factors: The solubility can be influenced by several factors such as:
    • Presence of hydroxyl groups which may enhance solubility in water.
    • Temperature: Generally, solubility tends to increase with rising temperatures.
  • Structure-Function Relationship: The intricate cyclic and functional group structures can lead to varied solubility patterns compared to simpler substitutes.
  • Common Solvent Compatibility: Typically, disodium salts have good solubility in aqueous solutions, making them more soluble than their neutral counterparts.

In conclusion, while disodium [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] phosphate may present challenges in solubility due to its structural complexity, its disodium form suggests potential for increased solubility particularly in polar solvents.

Interesting facts

Interesting Facts about Disodium; [2-(11,17-Dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] Phosphate

Disodium; [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] phosphate is an intriguing compound with numerous applications in the field of medicine and biochemistry. Here are some interesting aspects of this compound:

  • Pharmaceutical Relevance: This compound plays a significant role in drug formulations, particularly due to its ability to enhance the bioavailability of active pharmaceutical ingredients.
  • Antioxidant Properties: It exhibits strong antioxidant properties, which can help combat oxidative stress in biological systems, highlighting its potential therapeutic benefits.
  • Complex Structure: The intricate structure of this compound features a cyclopenta[a]phenanthren backbone. This complexity allows for unique interactions with biological molecules, making it a subject of study in medicinal chemistry.
  • Research Potential: Ongoing research explores its potential effects in areas such as cancer treatment, hormonal regulation, and neuroprotection, showing promise in improving human health.
  • Versatile Applications: Beyond pharmaceuticals, this compound is also tested in the field of biochemistry for synthesizing novel materials, thanks to its phosphate moiety that facilitates chemical bonding.

In summary, the intriguing structure and properties of disodium; [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] phosphate make it a valuable subject for scientific exploration. Whether it's paving the path for new medications or serving as inspiration for innovative material development, this compound warrants attention in both academic and industrial settings.

Synonyms
C21H27Na2O8P
Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, disodium salt, (11.beta.)-
Prednisolone phosphate sodium?
SCHEMBL1650407
VJZLQIPZNBPASX-UHFFFAOYSA-L
HMS5087N06
AKOS025394281
PD055213
disodium;[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] phosphate