Skip to main content

Disodium dexamethasone phosphate

ADVERTISEMENT
Identification
Molecular formula
C22H28FNa2O8P
CAS number
2392-39-4
IUPAC name
disodium;[2-[(17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] phosphate
State
State

Disodium dexamethasone phosphate is generally in the form of a solid under normal room temperature conditions. It is often supplied as a salt for enhanced water solubility and ease of use in pharmaceuticals.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
516.41g/mol
Molar mass
516.4100g/mol
Density
1.6000g/cm3
Appearence

Disodium dexamethasone phosphate typically appears as a white to off-white crystalline powder. It may also appear as granules. The compound is sensitive to light and may degrade upon exposure.

Comment on solubility

Solubility of Disodium [2-[(17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] phosphate

The solubility of the compound disodium [2-[(17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] phosphate is influenced by its unique chemical structure. Understanding its solubility is crucial for various applications in fields like pharmaceuticals and biochemistry.

General Observations:

  • Polarity: The presence of multiple hydroxyl groups contributes to a relatively high polarity, which typically enhances solubility in polar solvents such as water.
  • Ionic Nature: Being a disodium salt suggests that it may readily dissolve in aqueous solutions, as ionic compounds tend to dissociate in water.
  • Structural Complexity: The complexity of the organic moiety may hinder solubility to some extent based on steric factors and intermolecular interactions.

In summary, while the ionic characteristics likely promote solubility in polar solvents, the overall solubility of this compound may vary significantly based on the environmental conditions, such as pH and temperature. Further experimental data would be essential to encapsulate its solubility characteristics comprehensively.

Interesting facts

Interesting Facts about Disodium [2-[(17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] phosphate

This compound, often referred to by its structural description rather than a common name, is a fascinating example of a complex phosphate derivative. Here are some interesting points to consider:

  • Phosphate Backbone: The presence of the phosphate group in its structure highlights the significance of phosphorus in biological systems, particularly in energy transfer and storage as seen in ATP (adenosine triphosphate).
  • Steroidal Moiety: The compound incorporates a steroid-like structure, showcasing how modifications to such scaffolds can lead to diverse biological activities. Steroids are essential for various functions, including hormonal regulation and cell membrane integrity.
  • Structural Complexity: The intricate structure of this compound, with numerous chiral centers and functional groups, underscores the importance of stereochemistry in pharmaceutical design. Proper stereochemistry can influence how drugs interact with biological targets.
  • Potential Applications: Research into similar compounds often explores their potential as therapeutic agents, particularly in areas like cancer treatment or as anti-inflammatory drugs. Such compounds can also serve as lead structures for drug development.
  • Biological Relevance: Understanding compounds like this one helps scientists reveal insights into biochemical pathways and molecular interactions, enhancing our comprehension of both health and disease.

In conclusion, the exploration of disodium [2-[(17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] phosphate serves as a reminder of the profound complexity and beauty inherent in chemical compounds, where small changes can lead to significant biological impacts.