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Fluorescein sodium

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Identification
Molecular formula
C20H10Na2O5
CAS number
518-47-8
IUPAC name
disodium;2-(3-oxido-6-oxo-xanthen-9-yl)benzoate
State
State

At room temperature, fluorescein sodium is typically found as a solid in the form of a powder.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
376.28g/mol
Molar mass
376.2750g/mol
Density
1.6300g/cm3
Appearence

Fluorescein sodium is a bright orange-red to reddish-brown powder. When dissolved in water, it exhibits intense yellow-green fluorescence under ultraviolet or blue light, which makes it highly visible even at low concentrations.

Comment on solubility

Solubility of Disodium 2-(3-Oxido-6-Oxo-Xanthen-9-Yl)Benzoate

The solubility of disodium 2-(3-oxido-6-oxo-xanthen-9-yl)benzoate is an interesting subject due to its unique structure. This compound generally exhibits varying solubility in different solvents:

  • Water: Disodium salts often have improved solubility in water compared to their neutral counterparts. This is primarily due to the presence of the ionic disodium (Na2) component, which provides additional interactions with water molecules.
  • Organic Solvents: The solubility in organic solvents can be limited. Compounds with large aromatic portions, like this one, typically have reduced solubility in polar organic solvents.
  • Temperature Dependence: As with many compounds, solubility may increase with temperature, particularly in aqueous solutions. Hence, heating the solution could enhance the dissolution rate.

It is also important to note that solubility can be influenced by the surrounding pH. The statement "The more sodium ions present, the higher the solubility in ionic solutions" often holds true, leading to stronger interactions with the solvent.

In conclusion, understanding the solubility of disodium 2-(3-oxido-6-oxo-xanthen-9-yl)benzoate is pivotal for its application in various fields, especially in pharmaceuticals and dyes, where solubility characteristics are crucial for efficacy and stability.

Interesting facts

Interesting Facts about Disodium 2-(3-oxido-6-oxo-xanthen-9-yl)benzoate

Disodium 2-(3-oxido-6-oxo-xanthen-9-yl)benzoate, a fascinating chemical compound, is known for its pivotal role in various applications, particularly in the field of dyes and pigments. Here are some intriguing points about this compound:

  • Structure and Function: The compound features a complex structure that includes a xanthenone moiety, which contributes to its ability to absorb and emit light. This characteristic makes it essential in the formulation of fluorescent dyes.
  • pH Indicator: Disodium 2-(3-oxido-6-oxo-xanthen-9-yl)benzoate can act as a pH indicator due to its sensitivity to changes in hydrogen ion concentration, making it useful in titrations and chemical analysis.
  • Biocompatibility: Its biocompatibility allows it to be employed in biological sensing applications, where it can help visualize cellular processes and interactions in real-time.
  • Photostability: This compound exhibits good photostability, which is vital for applications that require long-term exposure to light without significant degradation of the dye's properties.
  • Synthetic Routes: Various synthetic pathways have been developed for the production of disodium 2-(3-oxido-6-oxo-xanthen-9-yl)benzoate, emphasizing the versatility of chemical synthesis and allowing for optimization in terms of yield and purity.

Overall, disodium 2-(3-oxido-6-oxo-xanthen-9-yl)benzoate not only exemplifies the beauty of complex organic chemistry but also highlights the practical applications of chemically engineered compounds in our everyday lives. Its role in advancing tools for science and technology cannot be overstated.

Synonyms
Fluorescein sodium
Uranine
Sodium fluorescein
Fluorescein, disodium salt
Fluor-I-Strip
Ki202
Funduscein-25
Ki202(1)
Ki202(2)
disodium 2-(6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
Spiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one, 3'6'-dihydroxy, disodium salt
FLUORESCEIN SODIUM (MART.)
FLUORESCEIN SODIUM [MART.]
BENZOIC ACID, 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-, DISODIUM SALT
FLUORESCEIN SODIUM (EP IMPURITY)
FLUORESCEIN SODIUM [EP IMPURITY]
FLUORESCEIN SODIUM (EP MONOGRAPH)
FLUORESCEIN SODIUM [EP MONOGRAPH]
FLUORESCEIN SODIUM (USP MONOGRAPH)
FLUORESCEIN SODIUM [USP MONOGRAPH]
Fluorescein, Sodium
Sodium, Fluorescein
D and C Yellow No. 8
Floures
Bioglo
Dry Eye Test
FLUORIN
Ak-fluor 10%
Ak-fluor 25%
FLUO-RECTAL
URANINE USP XII
3058 URANINE
FLUORESCEIN, WATER SOLUBLE
CALCOCID URANINE B 4315
C.I. 45350 SODIUM SALT
C.I. 766
FLUORESCEIN SODIUM COMPONENT OF ALTAFLUOR BENOX
3',6'-DIHYDROXY-SPIRO(ISOBENZOFURAN-1(3H),9'-(9H)XANTHENE)-3-ONE DISODIUM SALT
208-253-0
dtxcid905328
fluorescein disodium
fluorescein sodium salt
Fluorescein disodium salt
Soluble fluorescein
Uranin
C.I. 45350
C.I. Acid Yellow 73
Resorcinol phthalein sodium
Uranine WSS
Fluorescein, soluble
93X55PE38X
disodium;2-(3-oxido-6-oxoxanthen-9-yl)benzoate
CI 45350
Aizen uranine
Funduscein
Calcocid uranine B4315
Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-, sodium salt (1:2)
Fluor-I-strip A.T.
D&C Yellow No. 8
D & C Yellow no. 8
Flurenate
Furanium
Obiturine
Hidacid uranine
Uranine Yellow
Fluorescein LT
Uranine A
Uranine O
Ak-Fluor
Uranin A
Uranin S
Uranine A Extra
Uranine SS
Yellow 8
Soluble fluoresceine
Floures (TN)
Sodium fluoresceinate
Certiqual fluoresceine
Fluoresceinum natricum
Fluorescein Free Acid
Basacid Yellow 226
Fluorescein sodium B.P
11824 Yellow
12417 Yellow
Soluble Fluoresceine BPS
Japan Yellow 202(1)
Acid yellow 73 sodium salt
SCHEMBL264060
UNII-93X55PE38X
CI 45350 (Na salt)
CCRIS 6239
CHEMBL1628233
FLUORESCEIN SODIUM [JAN]
Fluorescein sodium (JP17/USP)
HSDB 8007
FLUORESCEIN SODIUM [VANDF]
MOLI001004
NCI-C54706
Fluorescein sodium [USP:BAN:JAN]
FLUORESCEIN SODIUM [WHO-DD]
FLUORESCEIN SODIUM [WHO-IP]
NSC 5070
EINECS 208-253-0
AKOS024364966
FLUORESCEIN DISODIUM SALT [MI]
FF09633
FLUORESCEIN SODIUM [ORANGE BOOK]
AS-17142
DA-63481
F0096
FLUORESCEINUM NATRICUM [WHO-IP LATIN]
EN300-73461
D02024
Disodium 6-hydroxy-3-oxo-9-xanthene-o-benzoate
Sodium salt of hydroxy-o-carboxy-phenyl-fluorone
Q27271622
Z1160865418
9-o-Carboxyphenyl-6-hydroxy-3-isoxanthone, disodium salt
disodium 9-(2-carboxylatophenyl)-3,6-dioxo-8aH-xanthen-8a-ide
3',6'-Dihydroxyspiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, disodium salt
Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-, disodium salt