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Folic acid

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Identification
Molecular formula
C19H17N7O6
CAS number
59-30-3
IUPAC name
disodium;2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioate
State
State

Folic acid is typically found in a solid state at room temperature. As a dietary supplement and in fortified foods, it is available in solid form, often as a powder or tablet.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
441.40g/mol
Molar mass
441.4030g/mol
Density
1.5920g/cm3
Appearence

Folic acid is a yellow to orange-yellow crystalline powder, sparingly soluble in water and soluble in dilute acids and alkaline solutions. It is almost odorless.

Comment on solubility

Solubility of Disodium 2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioate

The solubility of disodium 2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioate can be an intriguing topic due to its unique chemical structure. Understanding the solubility of this compound is essential for its practical applications, especially in biological systems. Here are some key points to consider:

  • Solvent Compatibility: This compound is typically soluble in polar solvents, primarily due to the presence of the disodium ion which enhances ionic interactions with water.
  • pH Dependence: The solubility can vary significantly with pH. Under acidic conditions, the compound may exhibit different solubility characteristics compared to neutral or alkaline conditions.
  • Ionic Strength: The overall ionic strength of the solution can affect solubility; higher ionic strength may lead to decreased solubility due to common ion effects.
  • Temperature Influence: Like many other compounds, increased temperature might improve solubility, facilitating greater interaction with solvent molecules.

In conclusion, the solubility of this compound is influenced by various factors including its ionic character, the presence of functional groups, and environmental conditions. Understanding these factors can help predict how this compound behaves in different solutions, making it a critical area of study in chemical sciences.

Interesting facts

Interesting Facts about Disodium 2-[[4-[(2,4-Diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioate

Disodium 2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioate is a fascinating compound that plays a significant role in biochemical research and pharmaceutical applications. Here are some intriguing aspects of this compound:

  • Biological Relevance: This compound is often investigated in the context of its potential anti-cancer properties. The pteridine moiety (2,4-diaminopteridin) is known for its role in the metabolism of nucleotides, making it essential in therapeutic research.
  • Mechanism of Action: Researchers are studying how the structural components of the compound can target specific biological pathways, particularly in cancer cells, by inhibiting folate synthesis, which is crucial for cell division.
  • Complex Structure: The intricate arrangement of functional groups within the compound, including the benzoyl and amino groups, offers multiple sites for interactions. This complexity can lead to various biological mechanisms worth exploring.
  • Potential Therapeutic Uses: Beyond oncology, compounds with similar structures may have applications in treating various conditions, including autoimmune diseases and infections, due to their ability to alter cell signaling pathways.
  • Research Challenges: While the potential is great, synthesizing and characterizing this compound can be challenging. Factors such as stability, reactivity, and bioavailability must be considered during research and development.

As a compound with a promising future in pharmacology, disodium 2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioate continues to attract the attention of scientists dedicated to uncovering its potential therapeutic benefits. The study of this compound exemplifies the intricate relationship between chemical structure and biological function, making it an exciting topic in the field of medicinal chemistry.

Synonyms
Aminopterinum natricum
7007-85-4
disodium;2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioate
Natrium 4-aminfolat
Aminopteroylglutamate sodium
Sodium aminopteroylglytamate
Sodium salt of N-(p-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)glutamic acid
SCHEMBL2504080
DTXSID70937990
N-(4-(((2,4-Diamino-6-pteridinyl)methyl)amino)benzoyl)glutaminsaeure dinatriumsalt
17146-80-4
Disodium 2-(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl]amino}benzamido)pentanedioate
Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-, monosodium salt, L-