Interesting facts
Interesting Facts about Disodium [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] Phosphate
This compound is an intriguing example of a complex organic phosphate, notable for its intricate structure and potential applications in various fields. Here are some fascinating facts that highlight its significance:
- Steroidal Framework: The core structure is based on a steroid skeleton, which is known for influencing a wide range of biological processes, from hormone regulation to cellular signaling.
- Fluorine Modifications: The presence of fluorine in this compound can enhance its biological activity, often leading to improved binding affinity to biological targets and increased metabolic stability.
- Phosphate Groups: Phosphates are crucial in biochemistry, particularly in energy transfer via ATP (adenosine triphosphate) and in various signaling pathways, indicating that this compound may play a role in these critical biochemical processes.
- Potential Therapeutic Applications: Due to the modification of the steroid framework, this compound may have potential applications in drug development, especially in the treatment of hormonal disorders or cancer therapeutics.
- Research Interest: The complexity of such compounds makes them a subject of intense research, with scientists studying their synthesis, reactivity, and interactions with biological macromolecules.
As we delve deeper into this compound's structural nuances, we can appreciate the ongoing efforts in organic chemistry to develop novel molecules that could lead to groundbreaking advances in medicine and biochemistry. The combination of its steroidal nature and phosphate functionality emphasizes the intricate interplay between structure and biological activity.
Synonyms
DEXAMETHASONE SODIUM PHOSPHATE
2392-39-4
Dexamethasone 21-phosphate disodium salt
Dalalone
Dexadreson
Megacort
Soldesam
Dexamethasone disodium phosphate
Decadron phosphate
Dexabene
Spersadox
Decdan
Dexagro
Solu-Decadron
Ak-Dex
Colvasone
Dexagel
Onadron
Baldex
Dexair
Sodium dexamethasone phosphate
Dexaject SP
Dexacen-4
Disodium dexamethasone phosphate
21-Disodium phosphate dexamethasone
EINECS 219-243-0
UNII-AI9376Y64P
MEPHAMESONE
SOLUDECADRON
TOTOCORTIN
CHEBI:4462
TLC399
Dexamethasone-21-phosphate disodium salt
DTXSID3047429
SOLUPEN N
TLC-399
AI9376Y64P
NSC-756722
9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate) disodium salt
DTXCID1027429
NSC 756722
DEXAMETHASONE PHOSPHATE (AS SODIUM)
Dexamethasone sodium phosphate [USP:BAN:JAN]
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11beta,16alpha)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methyl-, 21-(dihydrogen phosphate) disodium salt
NEODECADRON COMPONENT DEXAMETHASONE SODIUM PHOSPHATE
disodium 9-fluoro-11beta,17-dihydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate
DEXAMETHASONE SODIUM PHOSPHATE (MART.)
Dexamethasone sodium phosphate (USP:BAN:JAN)
DEXAMETHASONE SODIUM PHOSPHATE [MART.]
DEXAMETHASONE SODIUM PHOSPHATE (USP-RS)
DEXAMETHASONE SODIUM PHOSPHATE [USP-RS]
DEXAMETHASONE SODIUM PHOSPHATE (USP IMPURITY)
DEXAMETHASONE SODIUM PHOSPHATE [USP IMPURITY]
DEXAMETHASONE SODIUM PHOSPHATE (USP MONOGRAPH)
DEXAMETHASONE SODIUM PHOSPHATE [USP MONOGRAPH]
Cebedex
Dexacen
Topidex
Viadox
Dexamethasone SP
Dekasol LA
Dexium-SP
Dex-A-Vet Injection
DMT SUIK
ReadySharp Dexamethasone
dexamethasonedisodium phosphate
Dexamethasone Sodium Phosphates
dexamethasone surgical combo kit
MAS CARE-PAK DEXAMETHASONE
Dexamethasone Sodium Phosphate Inj.
dexamethasone phosphate disodium salt
Neuromaquel Neuroma/Anti-Inflammatory System
Cortaren Corticosteroid/Anti-Inflammatory System
DEXAMETHASONE SODIUM PHOSPHATE PRESERVATIVE FREE
DEXAMETHASONE SODIUM PHOSPHATE COMPONENT OF NEODECADRON
219-243-0
disodium 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-phosphate
prodex
solurex
55203-24-2
Orgadrone
Dexamethasone phosphate disodium
Dexamethasone 21-(disodium phosphate)
2392-39-4 (disodium)
MFCD00079105
disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
Maxidex Ointment
Hexadrol Injectable
sodium 2-((8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl phosphate
CAS-2392-39-4
Dexamethazone sodium phosphate
NCGC00094644-01
Dalalone (TN)
SCHEMBL7778
disodium [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
Dexadreson; Dexagel; Dexagro; Dexamethasone 21-(disodium phosphate)
CHEMBL2021430
BCP16805
Tox21_113181
Tox21_302586
s4028
AKOS015896357
AKOS015951212
CCG-269820
FD31952
KS-1150
NCGC00256783-01
AC-17992
Dexamethasone sodium phosphate (JAN/USP)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.alpha.)-
DEXAMETHASONE SODIUM PHOSPHATE [JAN]
NS00083368
DEXAMETHASONE SODIUM PHOSPHATE [VANDF]
EN300-52795
C08175
D00975
DEXAMETHASONE SODIUM PHOSPHATE [WHO-DD]
DEXAMETHASONE SODIUM PHOSPHATE [WHO-IP]
A830522
Dexamethasone 21-phosphate disodium salt, >=98%
DEXAMETHASONE SODIUM PHOSPHATE [GREEN BOOK]
DEXAMETHASONE SODIUM PHOSPHATE [EP MONOGRAPH]
DEXAMETHASONE SODIUM PHOSPHATE [ORANGE BOOK]
DEXAMETHASONI NATRII PHOSPHAS [WHO-IP LATIN]
DEXAMETHASONE 21-PHOSPHATE DISODIUM SALT [MI]
Q27106391
Dexamethasone sodium phosphate, British Pharmacopoeia (BP) Reference Standard
Dexamethasone sodium phosphate, European Pharmacopoeia (EP) Reference Standard
Dexamethasone sodium phosphate, United States Pharmacopeia (USP) Reference Standard
Dexamethasone 21-phosphate disodium;9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione disodium
Dexamethasone sodium phosphate for peak identification, European Pharmacopoeia (EP) Reference Standard
Dexamethasone Sodium Phosphate, Pharmaceutical Secondary Standard; Certified Reference Material
Disodium 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-phosphate
disodium (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-1-[2-(phosphonatooxy)acetyl]-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
disodium [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoranyl-10,13,16-trimethyl-11,17-bis(oxidanyl)-3-oxidanylidene-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxidanylidene-ethyl] phosphate
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, sodium salt (1:2), (11beta,16alpha)-
Solubility of Disodium 2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl phosphate
The solubility of disodium 2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl phosphate can be summarized as follows:
In summary, while disodium 2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl phosphate is generally soluble in water due to its ionic character, its behavior in solution can be influenced by both the solvent environment and the pH level. This highlights the intricate relationship between molecular structure and solubility, where “like dissolves like” serves as a fundamental guiding principle.