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Levothyroxine Sodium

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Identification
Molecular formula
C15H10I4NO4Na2
CAS number
25416-65-3
IUPAC name
disodium;2-amino-3-[3,5-diiodo-4-(3-iodo-4-oxido-phenoxy)phenyl]-2-methyl-propanoate
State
State

At room temperature, Levothyroxine Sodium is typically in a solid state. It is usually in the form of tablets or powders for pharmaceutical purposes.

Melting point (Celsius)
226.00
Melting point (Kelvin)
499.00
Boiling point (Celsius)
768.00
Boiling point (Kelvin)
1 041.00
General information
Molecular weight
798.85g/mol
Molar mass
798.8500g/mol
Density
1.4400g/cm3
Appearence

Levothyroxine sodium is generally a white or off-white crystalline powder that is often odorless. It is known for its hygroscopic properties, meaning it can absorb moisture from the environment. This characteristic must be considered when storing and handling the compound, as it may affect its stability and quality.

Comment on solubility

Solubility of Disodium 2-Amino-3-[3,5-Diiodo-4-(3-Iodo-4-Oxido-Phenoxy)Phenyl]-2-Methyl-Propanoate

The solubility of disodium 2-amino-3-[3,5-diiodo-4-(3-iodo-4-oxido-phenoxy)phenyl]-2-methyl-propanoate can be influenced by various factors including its ionic nature and the presence of functional groups. Being a disodium salt, this compound is expected to exhibit the following solubility characteristics:

  • High Solubility in Water: The presence of two sodium ions enhances the ability of the compound to dissolve in polar solvents such as water.
  • Influence of Iodine Atoms: Iodine's large atomic size and electronegativity might affect solubility behavior, potentially leading to lower solubility in non-polar solvents.
  • pH Dependence: As an amino acid derivative, solubility may also vary with changes in pH, which can alter the protonation state of the amino group.

In general, it can be noted that:

  1. Polar solvents are likely to enhance the solubility, whereas non-polar solvents may show reduced solubility.
  2. Temperature is also a critical factor; increasing temperature often increases solubility for many salts.
  3. The structure of the compound plays a role; specific functional groups may either hinder or promote interactions with the solvent.

To summarize, disodium 2-amino-3-[3,5-diiodo-4-(3-iodo-4-oxido-phenoxy)phenyl]-2-methyl-propanoate is expected to be quite soluble in water due to its ionic nature, influenced by its unique structural components. The overall solubility profile can vary based on environmental conditions and solvent selection.

Interesting facts

Interesting Facts about Disodium 2-Amino-3-[3,5-Diiodo-4-(3-Iodo-4-Oxido-Phenoxy)Phenyl]-2-Methyl-Propanoate

Disodium 2-amino-3-[3,5-diiodo-4-(3-iodo-4-oxido-phenoxy)phenyl]-2-methyl-propanoate is a unique compound that has raised interest in various scientific disciplines, particularly in pharmacology and biochemistry. Here are some intriguing points about this compound:

  • Structure Complexity: This compound showcases a highly complex structure with multiple iodine atoms, which can significantly enhance its biological activity. Iodine’s unique properties often lead to increased potency in medicinal applications.
  • Biological Significance: Iodinated compounds are frequently involved in thyroid hormone activity and can influence metabolic processes. The presence of amino group contributes to its potential in drug development, especially in the targeting of specific receptors.
  • Antimicrobial Properties: Many iodine-containing compounds are known for their antimicrobial activity. The presence of both diiodo and phenoxy groups positions this compound as a candidate for research into new antiseptics or antimicrobial agents.
  • Potential in Imaging: Iodine is an essential element in imaging techniques such as X-rays and CT scans. Compounds like this one may offer insights into new imaging agents, especially in molecular targeting approaches.

As with any chemical, research into disodium 2-amino-3-[3,5-diiodo-4-(3-iodo-4-oxido-phenoxy)phenyl]-2-methyl-propanoate should proceed with a thorough understanding of its interactions and effects. As Albert Einstein once said, "The most beautiful experience we can have is the mysterious." The exploration of this compound surely embodies that sentiment, opening doors to potentially transformative applications in medicine and technology.

Synonyms
DTXSID60274902
disodium 2-amino-3-[3,5-diiodo-4-(3-iodo-4-oxidophenoxy)phenyl]-2-methylpropanoate