Skip to main content

Iodixanol

ADVERTISEMENT
Identification
Molecular formula
C35H44I6N6Na2O15
CAS number
92339-11-2
IUPAC name
disodium;3-[[2-[2-(3-carboxylato-2,4,6-triiodo-anilino)-2-oxo-ethoxy]acetyl]amino]-2,4,6-triiodo-benzoate
State
State

At room temperature, iodixanol is generally used in solution form as it is highly soluble in water. In its pure form, it is a crystalline solid but it is administered in liquid form as a contrast agent for medical imaging procedures.

Melting point (Celsius)
245.00
Melting point (Kelvin)
518.15
Boiling point (Celsius)
908.20
Boiling point (Kelvin)
1 181.35
General information
Molecular weight
1550.20g/mol
Molar mass
1 550.1980g/mol
Density
2.0800g/cm3
Appearence

Iodixanol appears as a white to off-white crystalline powder. It is highly soluble in water and forms a clear solution when dissolved. The solution is colorless to pale yellow.

Comment on solubility

Solubility of Disodium 3-[[2-[2-(3-carboxylato-2,4,6-triiodo-anilino)-2-oxo-ethoxy]acetyl]amino]-2,4,6-triiodo-benzoate

Disodium 3-[[2-[2-(3-carboxylato-2,4,6-triiodo-anilino)-2-oxo-ethoxy]acetyl]amino]-2,4,6-triiodo-benzoate exhibits notable solubility properties that can vary significantly based on environmental conditions. The following points summarize its solubility characteristics:

  • Water Solubility: This compound is generally soluble in water, thanks to its disodium salt form, which enhances its ionic interactions with water molecules.
  • Influence of pH: The solubility may be influenced by the pH of the solution. In mildly alkaline conditions, the carboxylate groups can ionize, increasing solubility.
  • Temperature Effects: Increased temperatures may also improve solubility, as the kinetic energy of molecules leads to better interactions between solute and solvent.
  • Solvent Variety: While primarily soluble in water, the compound may also show differing solubility in organic solvents, depending on their polarity.

As noted, the solubility of this compound can be described as dynamic and subject to change under varying conditions. Such characteristics are crucial for applications in pharmaceuticals and dye chemistry, where delivery and reactivity are essential. Understanding the solubility profile allows for optimized formulation strategies and enhances the effectiveness of its use in various fields.

Interesting facts

Interesting Facts About Disodium 3-[[2-[2-(3-carboxylato-2,4,6-triiodo-anilino)-2-oxo-ethoxy]acetyl]amino]-2,4,6-triiodo-benzoate

Disodium 3-[[2-[2-(3-carboxylato-2,4,6-triiodo-anilino)-2-oxo-ethoxy]acetyl]amino]-2,4,6-triiodo-benzoate, often referred to for its complex structure, is a fascinating compound particularly recognized in the field of medical imaging. Here are some compelling aspects of this chemical:

  • Medical Applications: This compound is primarily used as a contrast agent in imaging techniques such as computed tomography (CT). Its ability to enhance visibility of blood vessels and soft tissues makes it invaluable in diagnostic procedures.
  • Iodine Content: With multiple iodine atoms incorporated into its structure, this compound boasts significant *radiopacity*, allowing it to absorb X-rays effectively. This property is crucial for enhancing the contrast of images obtained during medical scans.
  • Chemical Structure: The presence of carboxylate groups and anilino derivatives in its configuration illustrates how complex organic compounds can be tailored for specific functionalities. The structure can engage in various interactions at the molecular level, affecting both its solubility and reactivity.
  • Environmental Considerations: As research progresses, there is an increasing focus on the environmental impact of contrast agents, including this compound. Scientists are investigating ways to minimize any potential *bioaccumulation* and ensure that they are safe for both human use and ecological systems.
  • Innovative Research: Ongoing studies are exploring modifications to improve its efficacy and reduce adverse effects. This reflects a larger trend in pharmaceutical chemistry—designing drugs with enhanced performance and safety profiles.

In conclusion, disodium 3-[[2-[2-(3-carboxylato-2,4,6-triiodo-anilino)-2-oxo-ethoxy]acetyl]amino]-2,4,6-triiodo-benzoate isn't just a complex name; it's a testament to how chemistry intersects with healthcare, opening doors for advanced diagnostic techniques that save lives.

Synonyms
Ioglycamide disodium
IOGLYCAMIDE SODIUM
Sodium ioglycamate
Disodium ioglycamide
3737-71-1
SH-419
UQQ9SI8IO7
Benzoic acid, 3,3'-(oxybis((1-oxo-2,1-ethanediyl)imino))bis(2,4,6-triiodo-, disodium salt
Benzoic acid, 3,3'-(oxybis(methylenecarbonylimino))bis(2,4,6-triiodo-, disodium salt
Bilivistan sodium
UNII-UQQ9SI8IO7
Sodium ioglycamate [WHO-DD]
Bilivistan natrium
Bilivistan natrium [German]
NIOSH/DH6173000
DH61730000
Q27291211
Diglycolic acid di-(3-carboxy-2,4,6-triiodoanilide) disodium
Diglycolsaeure-di-(3-carboxy-2,4,6-trijod-anilid) dinatrium
Diglycolsaeure-di-(3-carboxy-2,4,6-trijod-anilid) dinatrium [German]
3,3'-(Oxydimethylenebis(carbonylimino))bis(2,4,6-triiodobenzoic acid) disodium salt
Benzoic acid, 3,3'-(oxydimethylenebis(carbonylimino))bis(2,4,6-triiodo-, disodium salt