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Levothyroxine sodium

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Identification
Molecular formula
C15H11O4I4Na2
CAS number
55-03-8
IUPAC name
disodium;3-(4-hydroxy-3,5-diiodo-phenyl)-2-phenyl-propanoate
State
State

At room temperature, levothyroxine sodium typically exists in a solid state. It is often provided in tablet or powder form for pharmaceutical use.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
798.86g/mol
Molar mass
798.8590g/mol
Density
1.3000g/cm3
Appearence

Levothyroxine sodium is typically a white to off-white, odorless, and tasteless crystalline powder. It may appear as small, fine particles or larger uniform crystals depending on the preparation method.

Comment on solubility

Solubility of Disodium 3-(4-hydroxy-3,5-diiodo-phenyl)-2-phenyl-propanoate

Disodium 3-(4-hydroxy-3,5-diiodo-phenyl)-2-phenyl-propanoate displays interesting solubility characteristics that can be pivotal in its applications. Here are some key points to consider:

  • Water Solubility: Being a disodium compound, it tends to be moderately soluble in water due to the presence of ionic bonds that facilitate dissolution.
  • Solvent Effects: The solubility may vary significantly when tested in different solvents. For example, while it is soluble in polar solvents, its solubility diminishes in non-polar solvents.
  • Temperature Dependence: The solubility is temperature-dependent; as the temperature increases, the solubility in water may also increase.
  • pH Influence: The solubility can be affected by the pH of the solution, leading to better solubility at certain pH levels due to the ionization of functional groups.

In summary, while disodium 3-(4-hydroxy-3,5-diiodo-phenyl)-2-phenyl-propanoate has reasonable solubility in aqueous environments, its solubility profile is markedly influenced by solvent choice, temperature, and pH. Thus, understanding these factors is essential for its effective use in various chemical applications.

Interesting facts

Interesting Facts about Disodium 3-(4-hydroxy-3,5-diiodo-phenyl)-2-phenyl-propanoate

Disodium 3-(4-hydroxy-3,5-diiodo-phenyl)-2-phenyl-propanoate, often referred to for its potential in biochemical applications, is noteworthy for several reasons:

  • Biological Significance: This compound is closely related to compounds studied for their roles in hormone regulation, specifically in the context of thyroid function due to the presence of iodinated phenyl groups.
  • Pharmaceutical Applications: The structural similarities of this compound to bioactive molecules make it a candidate for research in drug development, particularly in therapeutic interventions targeting hormonal imbalances.
  • Research Potential: Studies have suggested that its unique properties could facilitate new pathways in drug delivery systems, allowing for more effective therapeutic effects with reduced side effects.
  • Synthesis Challenges: The production of this compound involves intricate synthetic routes that require careful handling of iodinated reagents, emphasizing the importance of precision in organic synthesis.

Quote from the Field

As one researcher stated, "The careful manipulation of organic compounds like disodium 3-(4-hydroxy-3,5-diiodo-phenyl)-2-phenyl-propanoate not only unveils molecular intricacies but also paves the way for innovative medicinal applications."

From a chemistry student's perspective, exploring the structure and potential applications of such compounds offers a thrilling glimpse into the continuous push of scientific boundaries. Understanding the reactivity and stability of its bifunctional design could lead to groundbreaking advancements in medicinal chemistry.