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Iopromide

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Identification
Molecular formula
C18H24I3N3O8
CAS number
73334-07-3
IUPAC name
disodium;3-[[6-(3-carboxylato-2,4,6-triiodo-anilino)-6-oxo-hexanoyl]amino]-2,4,6-triiodo-benzoate
State
State

At room temperature, Iopromide is typically found in a liquid state when in solution form for medical applications.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
791.12g/mol
Molar mass
791.1220g/mol
Density
1.4450g/cm3
Appearence

Iopromide is a colorless to light yellow liquid. It is commonly used as a contrast agent in medical imaging due to its radiopaque properties. It is typically supplied in aqueous solution form and is non-ionic in nature.

Comment on solubility

Solubility Overview

The compound disodium 3-[[6-(3-carboxylato-2,4,6-triiodo-anilino)-6-oxo-hexanoyl]amino]-2,4,6-triiodo-benzoate exhibits intriguing solubility properties that are influenced by its structural components. The presence of both ionic and polar functional groups plays a significant role in its solubility characteristics.

Factors Affecting Solubility:

  • Ionic Strength: Being a disodium salt, it is likely to dissolve well in water due to the ionic interactions with water molecules.
  • Polar Functional Groups: The carboxylate group (-COO-) enhances solubility in polar solvents, promoting interaction and dispersion.
  • Hydrophobic Regions: The triiodo-anilino and benzoate structures may create hydrophobic patches, potentially limiting solubility in non-polar solvents.

In general, compounds like this with a mix of hydrophilic and hydrophobic parts often display the following solubility behavior:

  • Soluble in water due to ionic dissociation.
  • Partially soluble in alcohols depending on the alcohol's size and structure.
  • Practically insoluble in non-polar solvents due to the presence of ionic and polar groups.

As noted in literature, "the balance between hydrophilic and hydrophobic interactions determines the overall solubility of complex compounds." Thus, understanding the solubility of disodium 3-[[6-(3-carboxylato-2,4,6-triiodo-anilino)-6-oxo-hexanoyl]amino]-2,4,6-triiodo-benzoate requires careful consideration of both its ionic nature and the various functional groups present.

Interesting facts

Interesting Facts about Disodium;3-[[6-(3-carboxylato-2,4,6-triiodo-anilino)-6-oxo-hexanoyl]amino]-2,4,6-triiodo-benzoate

Disodium;3-[[6-(3-carboxylato-2,4,6-triiodo-anilino)-6-oxo-hexanoyl]amino]-2,4,6-triiodo-benzoate is a fascinating chemical compound known for its unique properties and applications primarily in the field of medicine and imaging. Here are some noteworthy aspects:

  • Medical Imaging: This compound is often utilized as a contrast agent in medical imaging techniques, particularly in X-ray and CT scans. Its high iodine content makes it highly effective for enhancing the visibility of internal structures.
  • Biocompatibility: Interestingly, disodium;3-[[6-(3-carboxylato-2,4,6-triiodo-anilino)-6-oxo-hexanoyl]amino]-2,4,6-triiodo-benzoate is designed to be biocompatible, meaning it can interact safely with biological tissues without causing significant adverse effects.
  • Targeted Drug Delivery: The complex structure of this compound allows it to potentially be used in targeted drug delivery systems, providing a path for medicinal agents to be directed precisely to the site of action while minimizing side effects.
  • Sustainability Aspects: In the realm of green chemistry, this compound can inspire research into developing more environmentally friendly contrast agents, reducing the ecological footprint of such materials in medical fields.
  • Chemical Structure: The intricate structure of disodium;3-[[6-(3-carboxylato-2,4,6-triiodo-anilino)-6-oxo-hexanoyl]amino]-2,4,6-triiodo-benzoate exemplifies the relationship between a compound's structure and its functionality. Understanding this can unlock further advancements in chemical applications in medicine.

In conclusion, disodium;3-[[6-(3-carboxylato-2,4,6-triiodo-anilino)-6-oxo-hexanoyl]amino]-2,4,6-triiodo-benzoate stands as a notable compound in scientific research, offering both practical applications and insights into chemical design and biocompatibility. Its role in enhancing medical imaging and potential for drug delivery systems highlights the importance of chemical compounds in advancing healthcare.

Synonyms
Iodipamide sodium
Sodium iodipamide
Cholografin sodium
Iodipamide disodium salt
Iodipamide, disodium salt
UNII-3J6WZA9PXS
3J6WZA9PXS
EINECS 220-049-3
Iodipamide sodium [USP]
Disodium N,N'-adiphylbis(3-amino-2,4,6-triiodobenzoic acid)
Iodipamide sodium (USP)
BENZOIC ACID, 3,3'-(ADIPOYLDIIMINO)BIS(2,4,6-TRIIODO-, DISODIUM SALT
220-049-3
2618-26-0
disodium 3,3'-[(1,6-dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodobenzoate]
Cholografin sodium; Disodium iodipamide; Iodipamide sodium
Biligrafin sodium
Disodium 3,3'-((1,6-dioxo-1,6-hexanediyl)diimino)bis(2,4,6-triiodobenzoate)
Biligrafin natrium
Biligrafin natrium [German]
SCHEMBL3855758
CHEMBL1200350
NIOSH/DH6836000
DTXSID20947226
SIZXNBZGPPPFHM-UHFFFAOYSA-L
IODIPAMIDE DISODIUM SALT [MI]
IODIPAMIDE SODIUM [ORANGE BOOK]
DH68360000
NS00081927
Q27257286
Adipic acid di-(3-carboxy-2,4,6-triiodoanilide) disodium
Adipinsaeure-di-(3-carboxy-2,4,6-trijod-anilid) dinatrium
Adipinsaeure-di-(3-carboxy-2,4,6-trijod-anilid) dinatrium [German]
Benzoic acid, 3,3'-(tetramethylenebis(carbonylimino))bis(2,4,6-triiodo-, disodium salt
Benzoic acid,3,3'-[(1,6-dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodo-,disodium salt(9ci)