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1-Docosanol

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Identification
Molecular formula
C22H46O
CAS number
661-19-8
IUPAC name
docosan-1-ol
State
State
1-Docosanol is a solid at room temperature, appearing as a waxy material.
Melting point (Celsius)
73.90
Melting point (Kelvin)
347.00
Boiling point (Celsius)
344.60
Boiling point (Kelvin)
617.80
General information
Molecular weight
326.61g/mol
Molar mass
326.6020g/mol
Density
0.8285g/cm3
Appearence

1-Docosanol is a waxy white solid with a faint characteristic odor. It takes the form of flakes or powder and can be relatively greasy to the touch due to its long carbon chain.

Comment on solubility

Solubility of Docosan-1-ol

Docosan-1-ol, with the chemical formula C22H46O, is a long-chain fatty alcohol that exhibits unique solubility characteristics due to its structure. Understanding the solubility of this compound is important for various applications, particularly in the field of biochemistry and material science.

General Solubility Behavior

As a long-chain alcohol, docosan-1-ol displays:

  • Limited Solubility in Water: Due to its lengthy hydrophobic hydrocarbon chain, docosan-1-ol is sparingly soluble in water. The hydrophilic hydroxyl group (-OH) is unable to sufficiently overcome the hydrophobic interactions of the long carbon chain.
  • Higher Solubility in Organic Solvents: This compound readily dissolves in non-polar organic solvents like hexane, ether, and chloroform. This is attributed to the similar non-polar nature of these solvents.
  • Temperature Dependence: The solubility of docosan-1-ol in organic solvents can increase with temperature, making it an important factor to consider during experiments or applications.

Application Considerations

When assessing the solubility of docosan-1-ol:

  • It is often used in formulations where low water solubility is desired.
  • Its solubility properties make it valuable in drug delivery systems where a non-polar matrix is involved.

In summary, docosan-1-ol's solubility profile highlights the complex interplay between hydrophilic and hydrophobic regions in chemical compounds, demonstrating the necessity for careful consideration in both research and industrial applications.

Interesting facts

Interesting Facts about Docosan-1-ol

Docosan-1-ol, known by its systematic name as docosanol, is a fascinating fatty alcohol that has garnered attention in various scientific fields. Here are some key insights regarding this compound:

  • Biological Significance: Docosan-1-ol is praised for its role in various biological processes. It is a long-chain fatty alcohol that serves as a building block for complex lipids, contributing to the structural integrity of cellular membranes.
  • Medicinal Properties: One of the most interesting applications of docosanol is its use in the pharmaceutical industry. It has been utilized as a topical treatment for herpes simplex virus infections, with studies indicating its efficacy in reducing the duration of outbreaks.
  • Source: This compound is naturally found in certain plant oils, such as those from the fruit of Physalis peruviana (golden berry) and the leaves of Ricinus communis (castor oil plant). This highlights its accessibility from natural resources.
  • Research Potential: Ongoing research is being conducted to explore the potential of docosan-1-ol in various areas, ranging from anti-inflammatory therapies to its role in skin care formulations. Its ability to enhance skin barrier function is particularly intriguing.
  • Environmental Stability: Docosan-1-ol shows a degree of stability in various environments, making it a compound of interest in both industrial applications and biochemical studies. Its long-chain structure contributes to its resilience and functional versatility.
  • Cosmetic Applications: Due to its emollient properties, docosan-1-ol is often included in cosmetic products to provide moisture and enhance skin texture. Its lipid-like characteristics make it an ideal ingredient for formulations targeting dry or sensitive skin.

Overall, docosan-1-ol exemplifies how simple chemical structures can hold complex significance across biological, medicinal, and industrial fields. As research continues, the full potential of this compound is likely to reveal even more benefits, cementing its place in both academic and commercial applications.

Synonyms
1-DOCOSANOL
Docosanol
docosan-1-ol
Behenyl alcohol
661-19-8
Behenic alcohol
Abreva
n-Docosanol
Docosyl alcohol
Lidavol
Stenol 1822
Lidakol
Lanette 22
Stenol 1822A
Nacol 22-97
30303-65-2
IK 2
NAA 422
IK.2
NSC 8407
HSDB 5739
NSC-8407
EINECS 211-546-6
UNII-9G1OE216XY
BRN 1770470
9G1OE216XY
CCRIS 8943
DTXSID4027286
CHEBI:31000
AI3-36489
DTXCID907286
NSC8407
EC 211-546-6
4-01-00-01906 (Beilstein Handbook Reference)
DOCOSANOL (II)
DOCOSANOL [II]
DOCOSANOL (MART.)
DOCOSANOL [MART.]
Cold Sore Fever Blister
Cold Sore Fever Blister Treatment
211-546-6
Tadenan
Docosanol [USAN]
Docosanol (Abreva)
Docosanol (USAN)
MFCD00002939
NCGC00159370-02
Docosanol (VAN)
C22H46O
Erazaban
Herepair
Healip
Cachalot BE-22
Abreva (TN)
Loxiol VPG 1451
n-Docosan-1-ol
Docosanol-(1)
1-Docosanol, 98%
DOCOSANOL [HSDB]
DOCOSANOL [VANDF]
N-DOCOSANOL [MI]
DOCOSANOL [WHO-DD]
SCHEMBL51925
DOCOSANOL [ORANGE BOOK]
CHEMBL1200453
HMS2093P22
Pharmakon1600-01505729
HY-B0222
Tox21_111611
LMFA05000008
NSC759235
s1637
AKOS015902887
CCG-213539
DB00632
NSC-759235
Behenyl alcohol, AI3-36489, Behenic alcohol, 1-Docosanol, Docosyl alcohol, IK-2, Tadenan
NCGC00159370-03
NCGC00159370-04
NCGC00159370-05
1-Docosanol, purum, >=97.0% (GC)
AC-19852
BP-41335
CAS-661-19-8
DA-69546
FD137295
SBI-0206938.P001
D0964
NS00009524
D03884
D70615
AB01563123_01
AB01563123_02
EN300-6495479
SR-05000001915
Q3033497
SR-05000001915-1
BRD-K50050533-001-02-1
BRD-K50050533-001-03-9
BRD-K50050533-001-04-7
A3D72D45-625E-49B5-B0FC-394010B3485D
InChI=1/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H