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Salicylic Acid and Dodecylamine

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Identification
Molecular formula
C12H17NO
CAS number
69-72-7 for salicylic acid; 124-22-1 for dodecylamine
IUPAC name
dodecan-1-amine;2-hydroxybenzoic acid
State
State

At room temperature, salicylic acid is usually in solid form, while dodecylamine can be a liquid or solid depending on the specific room temperature, as dodecylamine's melting point is close to ambient conditions.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
211.00
Boiling point (Kelvin)
484.15
General information
Molecular weight
183.27g/mol
Molar mass
182.2800g/mol
Density
1.4430g/cm3
Appearence

Salicylic acid is typically a white crystalline solid that is odorless or carries a very faint phenolic odor. Dodecylamine is a colorless to yellowish liquid or solid (depending on temperature) with an amine-like odor.

Comment on solubility

Solubility of Dodecan-1-amine; 2-hydroxybenzoic acid

The solubility of dodecan-1-amine; 2-hydroxybenzoic acid is influenced by several factors, primarily due to its unique structure comprising a long hydrophobic aliphatic chain and a hydrophilic aromatic component. Here are some key points to consider:

  • Hydrophobic Character: The long hydrocarbon chain of dodecan-1-amine contributes to its hydrophobic nature, which can restrict solubility in polar solvents such as water.
  • Hydrophilic Functional Groups: The presence of the hydroxy (–OH) group in 2-hydroxybenzoic acid enhances its ability to interact with water, potentially allowing for better solubility in aqueous environments.
  • Temperature Dependence: Like many organic compounds, the solubility of dodecan-1-amine; 2-hydroxybenzoic acid may increase with temperature due to enhanced molecular motion, leading to greater interactions with solvent molecules.
  • pH Sensitivity: The solubility can also vary with pH, especially since carboxylic acids can lose protons in basic conditions, thus increasing their solubility by yielding charged species.

In summary, while the long alkyl chain suggests limited solubility in polar solvents, the dual nature of dodecan-1-amine; 2-hydroxybenzoic acid, with its hydrophobic and hydrophilic components, offers a complex behavior that can lead to variable solubility in different environments. As such, it is often observed that when looking at solubility, one must consider the intricate balance between these contrasting characteristics.

Interesting facts

Interesting Facts about Dodecan-1-amine; 2-hydroxybenzoic acid

Dodecan-1-amine, also known as laurylamine, is a fascinating compound that belongs to the class of amines. Its unique structure grants it several noteworthy characteristics:

  • Chain Length: With a long aliphatic chain, dodecan-1-amine is a primary amine, meaning it contains a single amine group attached to a linear carbon chain. This gives it amphiphilic properties, making it valuable in both hydrophilic and lipophilic environments.
  • Applications in Industry: This compound is often used in the manufacture of surfactants, which are critical in various sectors including personal care products, detergents, and pharmaceuticals. Its ability to reduce surface tension enhances the effectiveness of these products.
  • Biological Significance: Dodecan-1-amine also plays a role in biological systems and may exhibit antimicrobial properties, making it of interest in biochemical research.

On the other hand, 2-hydroxybenzoic acid, commonly known as salicylic acid, holds significant importance in both chemistry and medicine:

  • Historical Use: Historically, salicylic acid was derived from willow bark and has been used for centuries in traditional medicine to treat pain and inflammation.
  • Acne Treatment: In modern times, it is well-known for its effectiveness as a topical treatment for acne, acting as a keratolytic agent that helps to unclog pores.
  • Anti-inflammatory Properties: Salicylic acid is also noted for its anti-inflammatory properties, which have made it a crucial component in numerous skincare products.

Together, dodecan-1-amine and 2-hydroxybenzoic acid represent the intersection of organic chemistry and practical applications in everyday life. As a scientist or chemistry student, understanding the properties and uses of these compounds can illuminate their role in technological advancements and health solutions. As the well-respected chemist Robert H. Grubbs once said, "Innovation in science is driven by the need to solve everyday problems." By exploring compounds like these, one contributes to that innovation!

Synonyms
Laurylamine salicylate
DODECYLAMINE SALICYLATE
7491-21-6
098DXT30J6
Caswell No. 413
dodecan-1-amine; 2-hydroxybenzoic acid
UNII-098DXT30J6
EINECS 231-311-1
EPA Pesticide Chemical Code 039302
Salicylic acid, compound with dodecylamine (1:1)
SCHEMBL2812099
DTXSID2075007
BDBHIKNRLLPPCL-UHFFFAOYSA-N
NS00082136
Q27236472