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Ethanehydroxamic acid

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Identification
Molecular formula
C2H5NO2
CAS number
495-78-3
IUPAC name
ethanehydroxamic acid
State
State

At room temperature, ethanehydroxamic acid is a solid.

Melting point (Celsius)
77.00
Melting point (Kelvin)
350.15
Boiling point (Celsius)
214.00
Boiling point (Kelvin)
487.15
General information
Molecular weight
75.07g/mol
Molar mass
75.0830g/mol
Density
1.1063g/cm3
Appearence

Ethanehydroxamic acid typically appears as a crystalline solid. It may appear as a white or off-white powder when purified.

Comment on solubility

Solubility of Ethanehydroxamic Acid (C2H5NO2)

Ethanehydroxamic acid, a compound with the formula C2H5NO2, exhibits interesting solubility characteristics that are worth discussing. It is primarily known for its association with the following solubility properties:

  • Solvent Compatibility: Ethanehydroxamic acid is typically soluble in polar solvents such as water and methanol, which is attributed to the presence of its hydroxamic acid functional group.
  • Temperature Dependence: The solubility can vary with temperature; generally, increased temperature enhances the solubility of organic compounds in water.
  • pH Influence: The solubility may also be affected by the pH of the solution. In more acidic environments, the protonation of the nitrogen within the hydroxamic group can increase solubility.

As a general consideration, compounds like ethanehydroxamic acid are often more soluble in polar rather than non-polar solvents due to their polar functional groups. This characteristic can be particularly important for applications in pharmaceuticals and agrochemicals, where solubility impacts bioavailability and activity.

In summary, the solubility of ethanehydroxamic acid is shaped by its structural properties and the environmental conditions of the medium in which it is dissolved. Understanding these traits enhances our ability to utilize this compound effectively in various chemical reactions.

Interesting facts

Interesting Facts about Ethanehydroxamic Acid

Ethanehydroxamic acid is a fascinating compound with various applications and properties that intrigue both scientists and chemistry students alike. Here are some noteworthy points about this compound:

  • Chemical Structure: Ethanehydroxamic acid features a unique structure similar to both carboxylic acids and hydroxylamine derivatives. This allows it to participate in diverse chemical reactions.
  • Functional Group: The presence of the hydroxamic acid functional group (-C(=O)NHOH) is what gives this compound its interesting reactivity. Hydroxamic acids are known for their ability to form metal complexes, making them valuable in coordination chemistry.
  • Biological Importance: Ethanehydroxamic acid and its derivatives have been studied for their biological activities, including antimicrobial and anti-inflammatory effects. Some studies suggest potential applications in drug development.
  • Metal Chelation: This compound is particularly noted for its ability to chelate metals. It can bind with transition metals, which is important in fields like catalysis and materials science.
  • Versatile Reactivity: Ethanehydroxamic acid can undergo various reactions, such as nucleophilic substitution and dehydration. Its versatility makes it a useful building block in organic synthesis.

In summary, ethanehydroxamic acid is not just an ordinary compound. Its intriguing structure, biological relevance, and capacity to form metal complexes open doors to exciting research opportunities. As chemists continue to explore its properties, who knows what new applications and discoveries await?

Synonyms
acetohydroxamic acid
N-Hydroxyacetamide
546-88-3
Lithostat
Methylhydroxamic acid
Acetic acid, oxime
Acetylhydroxamic acid
Acetohydroximic acid
N-Acetylhydroxylamine
Acetamide, N-hydroxy-
Acethydroxamsaeure
cetohyroxamic acid
N-Acetyl hydroxyacetamide
Acethydroxamsaure
Acethydroxamic acid
Acetohydroxamate
Acido acetohidroxamico
Acide acetohydroxamique
Hydroxylamine, N-acetyl-
Acidum acetohydroxamicum
Acetyl hydroxyamino
AHA
ACETOHYDROXAMICACID
n-hydroxy-acetamide
CCRIS 1730
NSC 176136
Acidum acetohydroxamicum [Latin]
HSDB 3585
EINECS 208-913-8
UNII-4RZ82L2GY5
MFCD00009994
NSC-176136
4RZ82L2GY5
DTXSID7022546
CHEBI:27777
AI3-62232
DTXCID802546
Acetamide, N-hydroxy- (9CI)
NSC176136
Acetohydroxamic acid [USAN:USP:INN]
NCGC00094576-01
WLN: QMV1
Acethydroxamsaeure [German]
Acidum acetohydroxamicum (Latin)
Acide acetohydroxamique [French]
Acido acetohidroxamico [Spanish]
ACETOHYDROXAMIC ACID (MART.)
ACETOHYDROXAMIC ACID [MART.]
ACETOHYDROXAMIC ACID (USP-RS)
ACETOHYDROXAMIC ACID [USP-RS]
Acetohydroxamic acid (USAN:USP:INN)
Lithostat (TN)
CAS-546-88-3
ACETOHYDROXAMIC ACID (USP MONOGRAPH)
ACETOHYDROXAMIC ACID [USP MONOGRAPH]
N-hydroxyacetimidic acid
N-hydroxyethanimidic acid
acetohydroxamsaure
Acetohydroxamic acid (USP/INN)
Acetic acid|oxime
acethydroximic acid
Acetohyroxamic acid
Acetyl hydroxyamine
Prestwick_38
acetohydroxamic-acid
N-oxidanylethanamide
acetohydroxarnic acid
methyl hydroximic acid
Spectrum_000020
Spectrum2_000109
Spectrum3_000285
Spectrum4_000138
Spectrum5_000812
CH3C(O)NHOH
2-Hydroxyamino-2-ethanal
CHEMBL734
Acetohydroxamic acid, 98%
BSPBio_001790
KBioGR_000556
KBioSS_000360
MLS001076662
DivK1c_000821
SPECTRUM1500103
SPBio_000098
Acetohydroxamic acid (Standard)
CHEBI:49029
HMS502J03
HY-B1235R
KBio1_000821
KBio2_000360
KBio2_002928
KBio2_005496
KBio3_001290
ACETOHYDROXAMIC ACID [MI]
G04BX03
NSC5073
NINDS_000821
ACETOHYDROXAMIC ACID (AHA)
ACETOHYDROXAMIC ACID [INN]
HMS1920A07
HMS2091G07
HMS2231M17
Pharmakon1600-01500103
ACETOHYDROXAMIC ACID [HSDB]
ACETOHYDROXAMIC ACID [USAN]
HY-B1235
NSC-5073
STR08084
ACETOHYDROXAMIC ACID [VANDF]
Tox21_111301
BDBM50099857
CCG-38927
GEO-00010
NSC755855
s4602
ACETOHYDROXAMIC ACID [WHO-DD]
AKOS000172340
Tox21_111301_1
AB01014
CS-4881
DB00551
FA10797
NSC-755855
IDI1_000821
NCGC00094576-02
NCGC00094576-03
NCGC00094576-05
ACETOHYDROXAMIC ACID [ORANGE BOOK]
BP-13320
SMR000499570
SBI-0051270.P003
DB-052632
A0051
NS00018656
EN300-36948
C06808
D00220
AB00051907_07
A830321
Q481822
SR-01000763642
SR-01000763642-2
BRD-K21615095-001-08-4
Z59181917
Acetohydroxamic acid, United States Pharmacopeia (USP) Reference Standard
208-913-8