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Phenobarbital

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Identification
Molecular formula
C12H12N2O3
CAS number
50-06-6
IUPAC name
ethanol;5-ethyl-5-phenyl-1-(1-piperidylmethyl)hexahydropyrimidine-2,4,6-trione
State
State

In room temperature, Phenobarbital is in a solid state.

Melting point (Celsius)
174.50
Melting point (Kelvin)
447.65
Boiling point (Celsius)
296.00
Boiling point (Kelvin)
569.15
General information
Molecular weight
232.24g/mol
Molar mass
232.2480g/mol
Density
1.1000g/cm3
Appearence

Phenobarbital typically appears as a white, odorless, crystalline powder. It is soluble in chloroform and slightly soluble in water and ethanol.

Comment on solubility

Solubility of Ethanol Derivative

The compound 5-ethyl-5-phenyl-1-(1-piperidylmethyl)hexahydropyrimidine-2,4,6-trione is an intriguing organic molecule whose solubility can be influenced by a variety of factors. In general, we can break down the solubility characteristics into a few key components:

  • Polarity: Due to the diverse functional groups within the compound, the overall polarity plays a large role in solubility. Compounds with polar characteristics typically show good solubility in polar solvents like water and alcohols.
  • Hydrogen Bonding: The presence of functional groups capable of hydrogen bonding, such as amines and triones, enhances solubility in solvent systems that can participate in these interactions.
  • Size and Structure: The bulky groups attached (like the ethyl and phenyl substituents) can affect the spatial arrangement, potentially leading to steric hindrance that might reduce solubility.

In terms of practical solubility, 5-ethyl-5-phenyl-1-(1-piperidylmethyl)hexahydropyrimidine-2,4,6-trione might exhibit:

  • Good solubility in organic solvents such as ethanol and methanol, due to similar polar characteristics.
  • Limited solubility in non-polar solvents, which can be expected given the complexity of its structure.

In summary, while predicting the exact solubility requires experimental data, understanding the influence of factors like polarity, hydrogen bonding capability, and molecular size can provide a solid foundation. Each characteristic interacts to define the solubility landscape of this fascinating compound.

Interesting facts

Interesting Facts about Ethanol; 5-Ethyl-5-phenyl-1-(1-piperidylmethyl)hexahydropyrimidine-2,4,6-trione

Ethanol, commonly known as alcohol, plays a significant role in both science and society. This specific compound, identified as 5-ethyl-5-phenyl-1-(1-piperidylmethyl)hexahydropyrimidine-2,4,6-trione, encompasses a complex structure that intrigues chemists and pharmaceutical researchers alike. Here are some fascinating aspects of this compound:

  • Pharmaceutical Potential: The unique structure of 5-ethyl-5-phenyl-1-(1-piperidylmethyl)hexahydropyrimidine-2,4,6-trione suggests it may exhibit biological activity, making it a candidate for drug development.
  • Versatile Solubility: Ethanol is often used as a solvent due to its ability to dissolve both polar and non-polar substances, encouraging reactions in diverse organic and biological contexts.
  • Cultural Significance: Ethanol has long been a staple in various cultures, serving as a social beverage, a basis for rituals, and a key component in the manufacture of alcoholic drinks.
  • Regulations and Safety: While ethanol is widely accepted for consumption, it is important to remember that regulated use and awareness of dosage are critical to avoid adverse health effects.
  • Research Insights: Studies on compounds similar to 5-ethyl-5-phenyl-1-(1-piperidylmethyl)hexahydropyrimidine-2,4,6-trione extend our understanding of molecular interactions, paving the way for innovations in medical treatments.

In conclusion, the exploration of ethanol and its derivatives not only uncovers the complexities of organic compounds but also opens doors to groundbreaking research in medicinal chemistry. As stated by chemists, "The design of new compounds inspired by established ones like ethanol is a journey towards enhancing human health and well-being." Whether through its recreational use or its potential medicinal applications, this compound continues to be a focal point of interest across multiple disciplines.

Synonyms
1-(Piperidinomethyl)phenobarbital alcoholate
5-Ethyl-5-phenyl-1-(piperidinomethyl)barbituric acid ethanolate
6733-91-1
BARBITURIC ACID, 5-ETHYL-5-PHENYL-1-(PIPERIDINOMETHYL)-, ETHANOLATE
DTXSID60986593
5-Ethyl-6-hydroxy-5-phenyl-3-[(piperidin-1-yl)methyl]pyrimidine-2,4(3H,5H)-dione--ethanol (1/1)