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Clozapine

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Identification
Molecular formula
C18H19ClN4
CAS number
5786-21-0
IUPAC name
ethanol;6-(3,4,5,6-tetrahydro-2H-azepin-1-ium-1-yl)-7H-benzo[d][1,3]benzodiazepine
State
State
At room temperature, clozapine is typically in a solid state, appearing as a crystalline powder.
Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
426.00
Boiling point (Kelvin)
699.15
General information
Molecular weight
326.83g/mol
Molar mass
326.8330g/mol
Density
1.2800g/cm3
Appearence
Clozapine typically appears as a pale yellow to yellow, crystalline powder. It has a faint odor and is practically insoluble in water, but soluble in some organic solvents such as ethanol and methanol.
Comment on solubility

Solubility of Ethanol; 6-(3,4,5,6-tetrahydro-2H-azepin-1-ium-1-yl)-7H-benzo[d][1,3]benzodiazepine

The solubility of the compound ethanol; 6-(3,4,5,6-tetrahydro-2H-azepin-1-ium-1-yl)-7H-benzo[d][1,3]benzodiazepine can be characterized by several key factors:

  • Polarity: The presence of the ethanol portion suggests a degree of polarity, which often enhances solubility in polar solvents such as water.
  • Structure: The complex cyclic structures within the benzo[d][1,3]benzodiazepine framework may influence solubility significantly because substituent groups can hinder or facilitate solvation.
  • Interactions: Ionizable moieties in the compound could engage in hydrogen bonding, further affecting its solubility profile.

It is often noted that:

"Like dissolves like." - a common phrase in chemistry, implying that polar solvents will typically dissolve polar compounds, and non-polar solvents will dissolve non-polar compounds.

This means that the solubility of this compound could be relatively high in organic solvents, as well as water, depending on the specific interactions that occur due to its unique chemical structure.
Overall, while definitive solubility data is crucial for practical applications, examining its molecular characteristics provides valuable insights into its expected behavior in various solvents.

Interesting facts

Exploring Ethanol; 6-(3,4,5,6-tetrahydro-2H-azepin-1-ium-1-yl)-7H-benzo[d][1,3]benzodiazepine

This intriguing compound, often referred to as a hybrid molecule, intertwines the properties of ethanol and a specific benzodiazepine analog. Here are some interesting facets of this compound:

  • Pharmaceutical Applications: The benzodiazepine structure is famously known for its tranquilizing effects, making this compound potentially significant in pharmacology for anxiety and sleep disorders.
  • Structure-Activity Relationship: The unique structure of the tetrahydro-azepine group may enhance the bioavailability and efficacy of the drug, suggesting a fascinating area for further research in medicinal chemistry.
  • Synergistic Effects: The incorporation of ethanol could result in synergy when interacting with neurotransmitter systems, allowing for a nuanced approach to drug interactions.
  • Chemical Diversity: This compound exemplifies the incredible diversity of chemical compounds, particularly in how slight structural variations can lead to vastly different biological activities.

As you delve into the study of this molecule, reflect on the interplay between chemistry and medicine. Ethanol, a simple molecule known for its widespread use, combines with a complex structure to spearhead research avenues in drug development. Ultimately, the exploration of such compounds can lead to breakthroughs that enhance our understanding of biochemical mechanisms and therapeutic potentials.

Synonyms
2870-28-2
C19H21N3.C2H6O