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Fentanyl

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Identification
Molecular formula
C22H28N2O8
CAS number
437-38-7
IUPAC name
ethyl 1-[1-(4-ethoxycarbonyl-4-phenyl-1-piperidyl)-2-phenyl-ethyl]-4-phenyl-piperidine-4-carboxylate
State
State

At room temperature, fentanyl is typically a solid, but it can be administered in various forms including liquid solutions.

Melting point (Celsius)
87.50
Melting point (Kelvin)
360.70
Boiling point (Celsius)
-34.50
Boiling point (Kelvin)
238.70
General information
Molecular weight
336.47g/mol
Molar mass
336.4690g/mol
Density
1.2320g/cm3
Appearence

Fentanyl is a white to off-white solid substance. It can appear as a crystalline powder or as a colorless liquid when in solutions.

Comment on solubility

Solubility of Ethyl 1-[1-(4-ethoxycarbonyl-4-phenyl-1-piperidyl)-2-phenyl-ethyl]-4-phenyl-piperidine-4-carboxylate

The solubility of this complex compound, ethyl 1-[1-(4-ethoxycarbonyl-4-phenyl-1-piperidyl)-2-phenyl-ethyl]-4-phenyl-piperidine-4-carboxylate, is influenced by several factors, including its structural characteristics and functional groups. Here are some key points to consider:

  • Polarity: The presence of polar functional groups, such as the ethoxycarbonyl and carboxylate moieties, suggests potential for solubility in polar solvents.
  • Hydrogen bonding: The ability to form hydrogen bonds may enhance solubility in water and other protic solvents, while reducing solubility in non-polar solvents.
  • Alkyl chain length: The ethyl group may introduce some hydrophobic character, affecting solubility in organic solvents differently compared to aqueous environments.

In summary, while ethyl 1-[1-(4-ethoxycarbonyl-4-phenyl-1-piperidyl)-2-phenyl-ethyl]-4-phenyl-piperidine-4-carboxylate is likely to exhibit solubility in a range of solvents, particularly polar ones, specific solubility details would require experimental data to fully understand its behavior in various conditions. As with many compounds, the overall solubility profile will be determined by a balance between its polar and non-polar attributes.

Interesting facts

Interesting Facts about Ethyl 1-[1-(4-ethoxycarbonyl-4-phenyl-1-piperidyl)-2-phenyl-ethyl]-4-phenyl-piperidine-4-carboxylate

This compound represents a fascinating intersection of piperidine and phenyl chemistry, showcasing the diverse applications and potential therapeutic benefits within medicinal chemistry. Here are some key points to consider:

  • Versatile Structure: The incorporation of both piperidine and phenyl groups enhances the compound's biological activity and specificity, making it a candidate for pharmacological research.
  • Potential Pharmacological Activity: Compounds similar to this one have been explored for various therapeutic areas, including anti-inflammatory, analgesic, and even anti-cancer properties.
  • Synthetic Efforts: The synthesis of such complex structures often requires multiple steps, using various methodologies such as coupling reactions and functional group modifications.
  • Role of the Ethyl Group: The ethyl group in this compound can enhance lipophilicity, which may affect how the compound interacts with biological membranes.
  • Importance of Carbonyl Groups: The presence of carbonyl groups in the structure points to potential reactivity and interactions with biomolecules, further underlining the significance of structural variations in drug design.

As you delve into the study of this compound, it opens up avenues not just for understanding its specific properties, but also for appreciating the intricate dance of molecular interactions in biological systems. In the words of a renowned chemist, "The beauty of a molecule lies not just in its composition, but in the stories it has to tell through its reactivity and interactions."


Ultimately, the study of ethyl 1-[1-(4-ethoxycarbonyl-4-phenyl-1-piperidyl)-2-phenyl-ethyl]-4-phenyl-piperidine-4-carboxylate represents a rich tapestry of chemical understanding, driving the quest for new and effective therapeutic agents.