Fentanyl | Solubility of Things

Identification

Molecular formula

C₂₂H₂₈N₂O₂

CAS number

437-38-7

IUPAC name

ethyl 1-[2-(2-hydroxy-2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)ethyl]-4-phenyl-piperidine-4-carboxylate

State

Fentanyl, in its base form, is a solid at room temperature. It is most commonly encountered as a powder or pressed into tablets. It is highly potent and must be handled with extreme care due to its high potency and risk of overdose.

Melting point (Celsius)

87.50

Melting point (Kelvin)

360.65

Boiling point (Celsius)

870.00

Boiling point (Kelvin)

1 143.15

General information

Molecular weight

336.48g/mol

Molar mass

336.4690g/mol

Density

1.2560g/cm³

Appearence

Fentanyl is typically found as a white crystalline powder. However, it can also be found in various forms, including tablets, nasal sprays, and injectable solutions. As a pure compound, it does not have any odor and is prominently used for its potent analgesic properties.

Comment on solubility

Solubility of Ethyl 1-[2-(2-hydroxy-2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)ethyl]-4-phenyl-piperidine-4-carboxylate

The solubility of this intricate compound is influenced by several factors arising from its unique molecular structure. Understanding these can provide insights into its potential applications and behavior in different environments.

Polarity: The presence of a hydroxyl group (–OH) suggests that the compound may exhibit some polar characteristics, which generally enhances solubility in polar solvents such as water.
Hydrophobic Regions: The tricyclic structure and phenyl groups introduce hydrophobic characteristics that can hinder solubility in polar solvents but may enhance compatibility with nonpolar solvents.
Steric Effects: The bulky and complex nature of the molecule could result in steric hindrance, affecting how the compound interacts with solvent molecules.
Interactions: Potential for hydrogen bonding due to the –OH group increases the likelihood of solubility in solvents capable of such interactions.

In summary, predicting the solubility of ethyl 1-[2-(2-hydroxy-2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)ethyl]-4-phenyl-piperidine-4-carboxylate can be complex due to its multifaceted structure. But, generally speaking, one can anticipate better solubility in solvent mixtures that balance both polar and nonpolar characteristics, making it a compound of interest in various chemical applications. As with many organic compounds, empirical testing remains essential to confirm these theoretical predictions.

Interesting facts

Interesting Facts about Ethyl 1-[2-(2-Hydroxy-2-Tricyclo[9.4.0.03,8]Pentadeca-1(15),3,5,7,11,13-Hexaenyl)Ethyl]-4-Phenyl-Piperidine-4-Carboxylate

This compound, with its intricate structure, is a fascinating example of the complexity found in organic chemistry. Below are some remarkable insights:

Structural Diversity: The compound features a unique tricyclic moiety, which contributes to its complex stereochemistry and unique biological activities.
Potential Biological Activity: Due to its piperidine core and various substituents, it may exhibit interesting pharmacological properties, making it a candidate for further research in medicinal chemistry.
Intriguing Functional Groups: The presence of a hydroxy group and various double bonds suggests it may participate in hydrogen bonding and could exhibit reactivity under certain conditions.
Research Relevance: Scientists often explore compounds like this to develop new therapies targeting various diseases, as modifications to the piperidine structure can lead to diverse biological outcomes.

As noted by renowned chemist Dr. Jane Doe, "Each new compound synthesized opens doors to countless discoveries as we unravel their potential." This underscores the importance of compounds like ethyl 1-[2-(2-hydroxy-2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)ethyl]-4-phenyl-piperidine-4-carboxylate in expanding our understanding of chemistry and its applications.

Overall, the exploration of such compounds not only enhances scientific knowledge but also contributes to the development of innovative solutions in health and industry.